BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

772 related articles for article (PubMed ID: 17585747)

  • 1. Antitumor agents 253. Design, synthesis, and antitumor evaluation of novel 9-substituted phenanthrene-based tylophorine derivatives as potential anticancer agents.
    Wei L; Shi Q; Bastow KF; Brossi A; Morris-Natschke SL; Nakagawa-Goto K; Wu TS; Pan SL; Teng CM; Lee KH
    J Med Chem; 2007 Jul; 50(15):3674-80. PubMed ID: 17585747
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Antitumor agents 251: synthesis, cytotoxic evaluation, and structure-activity relationship studies of phenanthrene-based tylophorine derivatives (PBTs) as a new class of antitumor agents.
    Wei L; Brossi A; Kendall R; Bastow KF; Morris-Natschke SL; Shi Q; Lee KH
    Bioorg Med Chem; 2006 Oct; 14(19):6560-9. PubMed ID: 16809043
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Expedient synthesis and structure-activity relationships of phenanthroindolizidine and phenanthroquinolizidine alkaloids.
    Chuang TH; Lee SJ; Yang CW; Wu PL
    Org Biomol Chem; 2006 Mar; 4(5):860-7. PubMed ID: 16493470
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design and synthesis of novel C14-hydroxyl substituted triptolide derivatives as potential selective antitumor agents.
    Li Z; Zhou ZL; Miao ZH; Lin LP; Feng HJ; Tong LJ; Ding J; Li YC
    J Med Chem; 2009 Aug; 52(16):5115-23. PubMed ID: 19637874
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis of phenanthroindolizidine alkaloids and evaluation of their antitumor activities and toxicities.
    Ikeda T; Yaegashi T; Matsuzaki T; Yamazaki R; Hashimoto S; Sawada S
    Bioorg Med Chem Lett; 2011 Oct; 21(19):5978-81. PubMed ID: 21865039
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Antitumor agents 268. Design, synthesis, and mechanistic studies of new 9-substituted phenanthrene-based tylophorine analogues as potent cytotoxic agents.
    Yang X; Shi Q; Liu YN; Zhao G; Bastow KF; Lin JC; Yang SC; Yang PC; Lee KH
    J Med Chem; 2009 Aug; 52(16):5262-8. PubMed ID: 19645447
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, Synthesis and in Vitro Evaluation of Tylophorine Derivatives as Possible Antitumor Agents.
    Mang Z; Zhang S; Bai J; Li M; Li H
    Chem Biodivers; 2020 Sep; 17(9):e2000066. PubMed ID: 32567792
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel prodrugs of tegafur that display improved anticancer activity and antiangiogenic properties.
    Engel D; Nudelman A; Tarasenko N; Levovich I; Makarovsky I; Sochotnikov S; Tarasenko I; Rephaeli A
    J Med Chem; 2008 Jan; 51(2):314-23. PubMed ID: 18163551
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Antitumor activity of imidazothioxanthones in murine and human tumor models in vitro and in vivo.
    Varvaresou A; Iakovou K; Gikas E; Fichtner I; Fiebig HH; Kelland LR; Double JA; Bibby MC; Hendriks HR
    Anticancer Res; 2004; 24(2B):907-19. PubMed ID: 15161044
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis, and antiviral evaluation of phenanthrene-based tylophorine derivatives as potential antiviral agents.
    Wang K; Hu Y; Liu Y; Mi N; Fan Z; Liu Y; Wang Q
    J Agric Food Chem; 2010 Dec; 58(23):12337-42. PubMed ID: 21058739
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and antitumor effect in vitro and in vivo of substituted 1,3-dihydroindole-2-ones.
    Christensen MK; Erichsen KD; Trojel-Hansen C; Tjørnelund J; Nielsen SJ; Frydenvang K; Johansen TN; Nielsen B; Sehested M; Jensen PB; Ikaunieks M; Zaichenko A; Loza E; Kalvinsh I; Björkling F
    J Med Chem; 2010 Oct; 53(19):7140-5. PubMed ID: 20845961
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Voreloxin, formerly SNS-595, has potent activity against a broad panel of cancer cell lines and in vivo tumor models.
    Hoch U; Lynch J; Sato Y; Kashimoto S; Kajikawa F; Furutani Y; Silverman JA
    Cancer Chemother Pharmacol; 2009 Jun; 64(1):53-65. PubMed ID: 18931998
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Antitumor agents 260. New desmosdumotin B analogues with improved in vitro anticancer activity.
    Nakagawa-Goto K; Bastow KF; Chen TH; Morris-Natschke SL; Lee KH
    J Med Chem; 2008 Jun; 51(11):3297-303. PubMed ID: 18473435
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological evaluation of imidazol-2-one derivatives as potential antitumor agents.
    Xue N; Yang X; Wu R; Chen J; He Q; Yang B; Lu X; Hu Y
    Bioorg Med Chem; 2008 Mar; 16(5):2550-7. PubMed ID: 18226907
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and evaluation of C-ring aromatized analogues of phenanthridone alkaloids.
    Lee S; Hwang S; Yu S; Jang W; Lee YM; Kim S
    Arch Pharm Res; 2011 Jul; 34(7):1065-70. PubMed ID: 21811912
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis and biological evaluation of substituted 11H-benzo[a]carbazole-5-carboxamides as novel antitumor agents.
    Wang YQ; Li XH; He Q; Chen Y; Xie YY; Ding J; Miao ZH; Yang CH
    Eur J Med Chem; 2011 Dec; 46(12):5878-84. PubMed ID: 22000922
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and biological evaluation of tylophorine-derived dibenzoquinolines as orally active agents: exploration of the role of tylophorine e ring on biological activity.
    Lee YZ; Yang CW; Hsu HY; Qiu YQ; Yeh TK; Chang HY; Chao YS; Lee SJ
    J Med Chem; 2012 Dec; 55(23):10363-77. PubMed ID: 23167614
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Antitumor agents. 194. Synthesis and biological evaluations of 4-beta-mono-, -di-, and -trisubstituted aniline-4'-O-demethyl-podophyllotoxin and related compounds with improved pharmacological profiles.
    Zhu XK; Guan J; Tachibana Y; Bastow KF; Cho SJ; Cheng HH; Cheng YC; Gurwith M; Lee KH
    J Med Chem; 1999 Jul; 42(13):2441-6. PubMed ID: 10395485
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure-activity studies of phenanthroindolizidine alkaloids as potential antitumor agents.
    Gao W; Bussom S; Grill SP; Gullen EA; Hu YC; Huang X; Zhong S; Kaczmarek C; Gutierrez J; Francis S; Baker DC; Yu S; Cheng YC
    Bioorg Med Chem Lett; 2007 Aug; 17(15):4338-42. PubMed ID: 17531481
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure-activity relationships of C-17 cyano-substituted estratrienes as anticancer agents.
    Leese MP; Jourdan FL; Gaukroger K; Mahon MF; Newman SP; Foster PA; Stengel C; Regis-Lydi S; Ferrandis E; Di Fiore A; De Simone G; Supuran CT; Purohit A; Reed MJ; Potter BV
    J Med Chem; 2008 Mar; 51(5):1295-308. PubMed ID: 18260615
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 39.