BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

254 related articles for article (PubMed ID: 17595523)

  • 1. A single binding motif is required for SPAK activation of the Na-K-2Cl cotransporter.
    Gagnon KB; England R; Delpire E
    Cell Physiol Biochem; 2007; 20(1-4):131-42. PubMed ID: 17595523
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Volume sensitivity of cation-Cl- cotransporters is modulated by the interaction of two kinases: Ste20-related proline-alanine-rich kinase and WNK4.
    Gagnon KB; England R; Delpire E
    Am J Physiol Cell Physiol; 2006 Jan; 290(1):C134-42. PubMed ID: 15930150
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Multiple pathways for protein phosphatase 1 (PP1) regulation of Na-K-2Cl cotransporter (NKCC1) function: the N-terminal tail of the Na-K-2Cl cotransporter serves as a regulatory scaffold for Ste20-related proline/alanine-rich kinase (SPAK) AND PP1.
    Gagnon KB; Delpire E
    J Biol Chem; 2010 May; 285(19):14115-21. PubMed ID: 20223824
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Characterization of SPAK and OSR1, regulatory kinases of the Na-K-2Cl cotransporter.
    Gagnon KB; England R; Delpire E
    Mol Cell Biol; 2006 Jan; 26(2):689-98. PubMed ID: 16382158
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterization of the interaction of the stress kinase SPAK with the Na+-K+-2Cl- cotransporter in the nervous system: evidence for a scaffolding role of the kinase.
    Piechotta K; Garbarini N; England R; Delpire E
    J Biol Chem; 2003 Dec; 278(52):52848-56. PubMed ID: 14563843
    [TBL] [Abstract][Full Text] [Related]  

  • 6. On the substrate recognition and negative regulation of SPAK, a kinase modulating Na+-K+-2Cl- cotransport activity.
    Gagnon KB; Delpire E
    Am J Physiol Cell Physiol; 2010 Sep; 299(3):C614-20. PubMed ID: 20463172
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Apoptosis-associated tyrosine kinase scaffolding of protein phosphatase 1 and SPAK reveals a novel pathway for Na-K-2C1 cotransporter regulation.
    Gagnon KB; England R; Diehl L; Delpire E
    Am J Physiol Cell Physiol; 2007 May; 292(5):C1809-15. PubMed ID: 17267545
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1.
    Vitari AC; Thastrup J; Rafiqi FH; Deak M; Morrice NA; Karlsson HK; Alessi DR
    Biochem J; 2006 Jul; 397(1):223-31. PubMed ID: 16669787
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Calcium-binding protein 39 facilitates molecular interaction between Ste20p proline alanine-rich kinase and oxidative stress response 1 monomers.
    Ponce-Coria J; Gagnon KB; Delpire E
    Am J Physiol Cell Physiol; 2012 Dec; 303(11):C1198-205. PubMed ID: 23034389
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A novel Ste20-related proline/alanine-rich kinase (SPAK)-independent pathway involving calcium-binding protein 39 (Cab39) and serine threonine kinase with no lysine member 4 (WNK4) in the activation of Na-K-Cl cotransporters.
    Ponce-Coria J; Markadieu N; Austin TM; Flammang L; Rios K; Welling PA; Delpire E
    J Biol Chem; 2014 Jun; 289(25):17680-8. PubMed ID: 24811174
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PKCdelta acts upstream of SPAK in the activation of NKCC1 by hyperosmotic stress in human airway epithelial cells.
    Smith L; Smallwood N; Altman A; Liedtke CM
    J Biol Chem; 2008 Aug; 283(32):22147-56. PubMed ID: 18550547
    [TBL] [Abstract][Full Text] [Related]  

  • 12. SPAK/OSR1 regulate NKCC1 and WNK activity: analysis of WNK isoform interactions and activation by T-loop trans-autophosphorylation.
    Thastrup JO; Rafiqi FH; Vitari AC; Pozo-Guisado E; Deak M; Mehellou Y; Alessi DR
    Biochem J; 2012 Jan; 441(1):325-37. PubMed ID: 22032326
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1).
    Piechotta K; Lu J; Delpire E
    J Biol Chem; 2002 Dec; 277(52):50812-9. PubMed ID: 12386165
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of NKCC2 by a chloride-sensing mechanism involving the WNK3 and SPAK kinases.
    Ponce-Coria J; San-Cristobal P; Kahle KT; Vazquez N; Pacheco-Alvarez D; de Los Heros P; Juárez P; Muñoz E; Michel G; Bobadilla NA; Gimenez I; Lifton RP; Hebert SC; Gamba G
    Proc Natl Acad Sci U S A; 2008 Jun; 105(24):8458-63. PubMed ID: 18550832
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Stimulation of human and mouse erythrocyte Na(+)-K(+)-2Cl(-) cotransport by osmotic shrinkage does not involve AMP-activated protein kinase, but is associated with STE20/SPS1-related proline/alanine-rich kinase activation.
    Sid B; Miranda L; Vertommen D; Viollet B; Rider MH
    J Physiol; 2010 Jul; 588(Pt 13):2315-28. PubMed ID: 20442269
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular determinants of hyperosmotically activated NKCC1-mediated K+/K+ exchange.
    Gagnon KB; Delpire E
    J Physiol; 2010 Sep; 588(Pt 18):3385-96. PubMed ID: 20530115
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PASK (proline-alanine-rich STE20-related kinase), a regulatory kinase of the Na-K-Cl cotransporter (NKCC1).
    Dowd BF; Forbush B
    J Biol Chem; 2003 Jul; 278(30):27347-53. PubMed ID: 12740379
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activation of the Na-K-Cl cotransporter NKCC1 detected with a phospho-specific antibody.
    Flemmer AW; Gimenez I; Dowd BF; Darman RB; Forbush B
    J Biol Chem; 2002 Oct; 277(40):37551-8. PubMed ID: 12145305
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulatory phosphorylation sites in the NH2 terminus of the renal Na-K-Cl cotransporter (NKCC2).
    Giménez I; Forbush B
    Am J Physiol Renal Physiol; 2005 Dec; 289(6):F1341-5. PubMed ID: 16077079
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regulation of NKCC2 activity by inhibitory SPAK isoforms: KS-SPAK is a more potent inhibitor than SPAK2.
    Park HJ; Curry JN; McCormick JA
    Am J Physiol Renal Physiol; 2013 Dec; 305(12):F1687-96. PubMed ID: 24133122
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.