BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

399 related articles for article (PubMed ID: 17596446)

  • 1. Widespread disruption of repressor element-1 silencing transcription factor/neuron-restrictive silencer factor occupancy at its target genes in Huntington's disease.
    Zuccato C; Belyaev N; Conforti P; Ooi L; Tartari M; Papadimou E; MacDonald M; Fossale E; Zeitlin S; Buckley N; Cattaneo E
    J Neurosci; 2007 Jun; 27(26):6972-83. PubMed ID: 17596446
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes.
    Zuccato C; Tartari M; Crotti A; Goffredo D; Valenza M; Conti L; Cataudella T; Leavitt BR; Hayden MR; Timmusk T; Rigamonti D; Cattaneo E
    Nat Genet; 2003 Sep; 35(1):76-83. PubMed ID: 12881722
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Binding of the repressor complex REST-mSIN3b by small molecules restores neuronal gene transcription in Huntington's disease models.
    Conforti P; Zuccato C; Gaudenzi G; Ieraci A; Camnasio S; Buckley NJ; Mutti C; Cotelli F; Contini A; Cattaneo E
    J Neurochem; 2013 Oct; 127(1):22-35. PubMed ID: 23800350
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Analysis of the repressor element-1 silencing transcription factor/neuron-restrictive silencer factor occupancy of non-neuronal genes in peripheral lymphocytes from patients with Huntington's disease.
    Marullo M; Valenza M; Mariotti C; Di Donato S; Cattaneo E; Zuccato C
    Brain Pathol; 2010 Jan; 20(1):96-105. PubMed ID: 19134002
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Loss of huntingtin function complemented by small molecules acting as repressor element 1/neuron restrictive silencer element silencer modulators.
    Rigamonti D; Bolognini D; Mutti C; Zuccato C; Tartari M; Sola F; Valenza M; Kazantsev AG; Cattaneo E
    J Biol Chem; 2007 Aug; 282(34):24554-62. PubMed ID: 17565993
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Rescue of gene expression by modified REST decoy oligonucleotides in a cellular model of Huntington's disease.
    Soldati C; Bithell A; Conforti P; Cattaneo E; Buckley NJ
    J Neurochem; 2011 Feb; 116(3):415-25. PubMed ID: 21105876
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Transcriptional dysregulation of coding and non-coding genes in cellular models of Huntington's disease.
    Bithell A; Johnson R; Buckley NJ
    Biochem Soc Trans; 2009 Dec; 37(Pt 6):1270-5. PubMed ID: 19909260
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Functional roles for the striatal-enriched transcription factor, Bcl11b, in the control of striatal gene expression and transcriptional dysregulation in Huntington's disease.
    Desplats PA; Lambert JR; Thomas EA
    Neurobiol Dis; 2008 Sep; 31(3):298-308. PubMed ID: 18595722
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease.
    Zuccato C; Ciammola A; Rigamonti D; Leavitt BR; Goffredo D; Conti L; MacDonald ME; Friedlander RM; Silani V; Hayden MR; Timmusk T; Sipione S; Cattaneo E
    Science; 2001 Jul; 293(5529):493-8. PubMed ID: 11408619
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Repressor element-1 silencing transcription factor (REST) is present in human control and Huntington's disease neurones.
    Schiffer D; Caldera V; Mellai M; Conforti P; Cattaneo E; Zuccato C
    Neuropathol Appl Neurobiol; 2014 Dec; 40(7):899-910. PubMed ID: 24634989
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Expression of the rat m4 muscarinic acetylcholine receptor gene is regulated by the neuron-restrictive silencer element/repressor element 1.
    Mieda M; Haga T; Saffen DW
    J Biol Chem; 1997 Feb; 272(9):5854-60. PubMed ID: 9038202
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Turning REST/NRSF dysfunction in Huntington's disease into a pharmaceutical target.
    Rigamonti D; Mutti C; Zuccato C; Cattaneo E; Contini A
    Curr Pharm Des; 2009; 15(34):3958-67. PubMed ID: 19751206
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Brain-derived neurotrophic factor regulates the onset and severity of motor dysfunction associated with enkephalinergic neuronal degeneration in Huntington's disease.
    Canals JM; Pineda JR; Torres-Peraza JF; Bosch M; Martín-Ibañez R; Muñoz MT; Mengod G; Ernfors P; Alberch J
    J Neurosci; 2004 Sep; 24(35):7727-39. PubMed ID: 15342740
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Transcriptional repression by neuron-restrictive silencer factor is mediated via the Sin3-histone deacetylase complex.
    Roopra A; Sharling L; Wood IC; Briggs T; Bachfischer U; Paquette AJ; Buckley NJ
    Mol Cell Biol; 2000 Mar; 20(6):2147-57. PubMed ID: 10688661
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of repressor element 1 in cytochrome P450 genes and their negative regulation by RE1 silencing transcription factor/neuron-restrictive silencer factor.
    García-Sánchez R; Ayala-Luján J; Hernández-Peréz A; Mendoza-Figueroa T; Tapia-Ramírez J
    Biochim Biophys Acta; 2003 Mar; 1620(1-3):39-46. PubMed ID: 12595071
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Genome-wide analysis of repressor element 1 silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) target genes.
    Bruce AW; Donaldson IJ; Wood IC; Yerbury SA; Sadowski MI; Chapman M; Göttgens B; Buckley NJ
    Proc Natl Acad Sci U S A; 2004 Jul; 101(28):10458-63. PubMed ID: 15240883
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dysregulation of REST-regulated coding and non-coding RNAs in a cellular model of Huntington's disease.
    Soldati C; Bithell A; Johnston C; Wong KY; Stanton LW; Buckley NJ
    J Neurochem; 2013 Feb; 124(3):418-30. PubMed ID: 23145961
    [TBL] [Abstract][Full Text] [Related]  

  • 18. BDNF overexpression in the forebrain rescues Huntington's disease phenotypes in YAC128 mice.
    Xie Y; Hayden MR; Xu B
    J Neurosci; 2010 Nov; 30(44):14708-18. PubMed ID: 21048129
    [TBL] [Abstract][Full Text] [Related]  

  • 19. REST4-mediated modulation of REST/NRSF-silencing function during BDNF gene promoter activation.
    Tabuchi A; Yamada T; Sasagawa S; Naruse Y; Mori N; Tsuda M
    Biochem Biophys Res Commun; 2002 Jan; 290(1):415-20. PubMed ID: 11779185
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Diminished activity-dependent brain-derived neurotrophic factor expression underlies cortical neuron microcircuit hypoconnectivity resulting from exposure to mutant huntingtin fragments.
    Gambazzi L; Gokce O; Seredenina T; Katsyuba E; Runne H; Markram H; Giugliano M; Luthi-Carter R
    J Pharmacol Exp Ther; 2010 Oct; 335(1):13-22. PubMed ID: 20624994
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.