161 related articles for article (PubMed ID: 17596707)
1. BACE1 and mutated presenilin-1 differently modulate Abeta40 and Abeta42 levels and cerebral amyloidosis in APPDutch transgenic mice.
Herzig MC; Paganetti P; Staufenbiel M; Jucker M
Neurodegener Dis; 2007; 4(2-3):127-35. PubMed ID: 17596707
[TBL] [Abstract][Full Text] [Related]
2. Abeta is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis.
Herzig MC; Winkler DT; Burgermeister P; Pfeifer M; Kohler E; Schmidt SD; Danner S; Abramowski D; Stürchler-Pierrat C; Bürki K; van Duinen SG; Maat-Schieman ML; Staufenbiel M; Mathews PM; Jucker M
Nat Neurosci; 2004 Sep; 7(9):954-60. PubMed ID: 15311281
[TBL] [Abstract][Full Text] [Related]
3. Cerebral amyloid angiopathy: pathogenetic mechanisms and link to dense amyloid plaques.
Kumar-Singh S
Genes Brain Behav; 2008 Feb; 7 Suppl 1():67-82. PubMed ID: 18184371
[TBL] [Abstract][Full Text] [Related]
4. In vivo beta-secretase 1 inhibition leads to brain Abeta lowering and increased alpha-secretase processing of amyloid precursor protein without effect on neuregulin-1.
Sankaranarayanan S; Price EA; Wu G; Crouthamel MC; Shi XP; Tugusheva K; Tyler KX; Kahana J; Ellis J; Jin L; Steele T; Stachel S; Coburn C; Simon AJ
J Pharmacol Exp Ther; 2008 Mar; 324(3):957-69. PubMed ID: 18156464
[TBL] [Abstract][Full Text] [Related]
5. Astrocytic expression of the Alzheimer's disease beta-secretase (BACE1) is stimulus-dependent.
Hartlage-Rübsamen M; Zeitschel U; Apelt J; Gärtner U; Franke H; Stahl T; Günther A; Schliebs R; Penkowa M; Bigl V; Rossner S
Glia; 2003 Jan; 41(2):169-79. PubMed ID: 12509807
[TBL] [Abstract][Full Text] [Related]
6. Presenilin 1 is involved in the maturation of beta-site amyloid precursor protein-cleaving enzyme 1 (BACE1).
Kuzuya A; Uemura K; Kitagawa N; Aoyagi N; Kihara T; Ninomiya H; Ishiura S; Takahashi R; Shimohama S
J Neurosci Res; 2007 Jan; 85(1):153-65. PubMed ID: 17075903
[TBL] [Abstract][Full Text] [Related]
7. Prominent cerebral amyloid angiopathy in transgenic mice overexpressing the london mutant of human APP in neurons.
Van Dorpe J; Smeijers L; Dewachter I; Nuyens D; Spittaels K; Van Den Haute C; Mercken M; Moechars D; Laenen I; Kuiperi C; Bruynseels K; Tesseur I; Loos R; Vanderstichele H; Checler F; Sciot R; Van Leuven F
Am J Pathol; 2000 Oct; 157(4):1283-98. PubMed ID: 11021833
[TBL] [Abstract][Full Text] [Related]
8. Deficient cerebral clearance of vasculotropic mutant Dutch/Iowa Double A beta in human A betaPP transgenic mice.
Davis J; Xu F; Miao J; Previti ML; Romanov G; Ziegler K; Van Nostrand WE
Neurobiol Aging; 2006 Jul; 27(7):946-54. PubMed ID: 16105708
[TBL] [Abstract][Full Text] [Related]
9. S-Adenosylhomocysteine increases beta-amyloid formation in BV-2 microglial cells by increased expressions of beta-amyloid precursor protein and presenilin 1 and by hypomethylation of these gene promoters.
Lin HC; Hsieh HM; Chen YH; Hu ML
Neurotoxicology; 2009 Jul; 30(4):622-7. PubMed ID: 19635394
[TBL] [Abstract][Full Text] [Related]
10. Cerebral amyloid angiopathy and dementia.
Tian J; Shi J; Mann DM
Panminerva Med; 2004 Dec; 46(4):253-64. PubMed ID: 15876981
[TBL] [Abstract][Full Text] [Related]
11. Differential effects of gamma-secretase and BACE1 inhibition on brain Abeta levels in vitro and in vivo.
Elvang AB; Volbracht C; Pedersen LØ; Jensen KG; Karlsson JJ; Larsen SA; Mørk A; Stensbøl TB; Bastlund JF
J Neurochem; 2009 Sep; 110(5):1377-87. PubMed ID: 19519664
[TBL] [Abstract][Full Text] [Related]
12. Caffeine protects Alzheimer's mice against cognitive impairment and reduces brain beta-amyloid production.
Arendash GW; Schleif W; Rezai-Zadeh K; Jackson EK; Zacharia LC; Cracchiolo JR; Shippy D; Tan J
Neuroscience; 2006 Nov; 142(4):941-52. PubMed ID: 16938404
[TBL] [Abstract][Full Text] [Related]
13. Decreased Abeta secretion by cells expressing familial Alzheimer's disease-linked mutant presenilin 1.
Shimojo M; Sahara N; Murayama M; Ichinose H; Takashima A
Neurosci Res; 2007 Mar; 57(3):446-53. PubMed ID: 17210196
[TBL] [Abstract][Full Text] [Related]
14. Relative paucity of tau accumulation in the small areas with abundant Abeta42-positive capillary amyloid angiopathy within a given cortical region in the brain of patients with Alzheimer pathology.
Oshima K; Akiyama H; Tsuchiya K; Kondo H; Haga C; Shimomura Y; Iseki E; Uchikado H; Kato M; Niizato K; Arai H
Acta Neuropathol; 2006 Jun; 111(6):510-8. PubMed ID: 16718347
[TBL] [Abstract][Full Text] [Related]
15. Distinct mechanisms by mutant presenilin 1 and 2 leading to increased intracellular levels of amyloid beta-protein 42 in Chinese hamster ovary cells.
Qi Y; Morishima-Kawashima M; Sato T; Mitsumori R; Ihara Y
Biochemistry; 2003 Feb; 42(4):1042-52. PubMed ID: 12549925
[TBL] [Abstract][Full Text] [Related]
16. Altered expression and distribution of zinc transporters in APP/PS1 transgenic mouse brain.
Zhang LH; Wang X; Zheng ZH; Ren H; Stoltenberg M; Danscher G; Huang L; Rong M; Wang ZY
Neurobiol Aging; 2010 Jan; 31(1):74-87. PubMed ID: 18378045
[TBL] [Abstract][Full Text] [Related]
17. P-glycoprotein efflux and other factors limit brain amyloid beta reduction by beta-site amyloid precursor protein-cleaving enzyme 1 inhibitors in mice.
Meredith JE; Thompson LA; Toyn JH; Marcin L; Barten DM; Marcinkeviciene J; Kopcho L; Kim Y; Lin A; Guss V; Burton C; Iben L; Polson C; Cantone J; Ford M; Drexler D; Fiedler T; Lentz KA; Grace JE; Kolb J; Corsa J; Pierdomenico M; Jones K; Olson RE; Macor JE; Albright CF
J Pharmacol Exp Ther; 2008 Aug; 326(2):502-13. PubMed ID: 18499745
[TBL] [Abstract][Full Text] [Related]
18. Dynamics of Abeta turnover and deposition in different beta-amyloid precursor protein transgenic mouse models following gamma-secretase inhibition.
Abramowski D; Wiederhold KH; Furrer U; Jaton AL; Neuenschwander A; Runser MJ; Danner S; Reichwald J; Ammaturo D; Staab D; Stoeckli M; Rueeger H; Neumann U; Staufenbiel M
J Pharmacol Exp Ther; 2008 Nov; 327(2):411-24. PubMed ID: 18687920
[TBL] [Abstract][Full Text] [Related]
19. Enhanced accumulation of phosphorylated alpha-synuclein in double transgenic mice expressing mutant beta-amyloid precursor protein and presenilin-1.
Kurata T; Kawarabayashi T; Murakami T; Miyazaki K; Morimoto N; Ohta Y; Takehisa Y; Nagai M; Ikeda M; Matsubara E; Westaway D; Hyslop PS; Harigaya Y; Kamiya T; Shoji M; Abe K
J Neurosci Res; 2007 Aug; 85(10):2246-52. PubMed ID: 17526016
[TBL] [Abstract][Full Text] [Related]
20. Reduced retinal function in amyloid precursor protein-over-expressing transgenic mice via attenuating glutamate-N-methyl-d-aspartate receptor signaling.
Shimazawa M; Inokuchi Y; Okuno T; Nakajima Y; Sakaguchi G; Kato A; Oku H; Sugiyama T; Kudo T; Ikeda T; Takeda M; Hara H
J Neurochem; 2008 Oct; 107(1):279-90. PubMed ID: 18691390
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
