These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

194 related articles for article (PubMed ID: 17602463)

  • 1. Computer-aided rational drug design: a novel agent (SR13668) designed to mimic the unique anticancer mechanisms of dietary indole-3-carbinol to block Akt signaling.
    Chao WR; Yean D; Amin K; Green C; Jong L
    J Med Chem; 2007 Jul; 50(15):3412-5. PubMed ID: 17602463
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A potent indole-3-carbinol derived antitumor agent with pleiotropic effects on multiple signaling pathways in prostate cancer cells.
    Weng JR; Tsai CH; Kulp SK; Wang D; Lin CH; Yang HC; Ma Y; Sargeant A; Chiu CF; Tsai MH; Chen CS
    Cancer Res; 2007 Aug; 67(16):7815-24. PubMed ID: 17699787
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pharmacokinetics and enhanced bioavailability of candidate cancer preventative agent, SR13668 in dogs and monkeys.
    Kapetanovic IM; Muzzio M; Hu SC; Crowell JA; Rajewski RA; Haslam JL; Jong L; McCormick DL
    Cancer Chemother Pharmacol; 2010 May; 65(6):1109-16. PubMed ID: 19756605
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A novel class of achiral seco-analogs of CC-1065 and the duocarmycins: design, synthesis, DNA binding, and anticancer properties.
    Kupchinsky S; Centioni S; Howard T; Trzupek J; Roller S; Carnahan V; Townes H; Purnell B; Price C; Handl H; Summerville K; Johnson K; Toth J; Hudson S; Kiakos K; Hartley JA; Lee M
    Bioorg Med Chem; 2004 Dec; 12(23):6221-36. PubMed ID: 15519165
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis and anticancer activities of hybrids of indole and barbituric acids--identification of highly promising leads.
    Singh P; Kaur M; Verma P
    Bioorg Med Chem Lett; 2009 Jun; 19(11):3054-8. PubMed ID: 19398334
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis and biological evaluation of substituted 11H-benzo[a]carbazole-5-carboxamides as novel antitumor agents.
    Wang YQ; Li XH; He Q; Chen Y; Xie YY; Ding J; Miao ZH; Yang CH
    Eur J Med Chem; 2011 Dec; 46(12):5878-84. PubMed ID: 22000922
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A novel class of in vivo active anticancer agents: achiral seco-amino- and seco-hydroxycyclopropylbenz[e]indolone (seco-CBI) analogues of the duocarmycins and CC-1065.
    Sato A; McNulty L; Cox K; Kim S; Scott A; Daniell K; Summerville K; Price C; Hudson S; Kiakos K; Hartley JA; Asao T; Lee M
    J Med Chem; 2005 Jun; 48(11):3903-18. PubMed ID: 15916443
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Rapid evolution of 6-phenylpurine inhibitors of protein kinase B through structure-based design.
    Donald A; McHardy T; Rowlands MG; Hunter LJ; Davies TG; Berdini V; Boyle RG; Aherne GW; Garrett MD; Collins I
    J Med Chem; 2007 May; 50(10):2289-92. PubMed ID: 17451235
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and identification of novel indolo[2,3-a]pyrimido[5,4-c]carbazoles as a new class of anti-cancer agents.
    Pierce LT; Cahill MM; Winfield HJ; McCarthy FO
    Eur J Med Chem; 2012 Oct; 56():292-300. PubMed ID: 22910137
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Allosteric inhibitors of Akt1 and Akt2: a naphthyridinone with efficacy in an A2780 tumor xenograft model.
    Bilodeau MT; Balitza AE; Hoffman JM; Manley PJ; Barnett SF; Defeo-Jones D; Haskell K; Jones RE; Leander K; Robinson RG; Smith AM; Huber HE; Hartman GD
    Bioorg Med Chem Lett; 2008 Jun; 18(11):3178-82. PubMed ID: 18479914
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel carbazole and acyl-indole antimitotics.
    Barta TE; Barabasz AF; Foley BE; Geng L; Hall SE; Hanson GJ; Jenks M; Ma W; Rice JW; Veal J
    Bioorg Med Chem Lett; 2009 Jun; 19(11):3078-80. PubMed ID: 19394222
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel arylsulfoanilide-oxindole hybrid as an anticancer agent that inhibits translation initiation.
    Natarajan A; Guo Y; Harbinski F; Fan YH; Chen H; Luus L; Diercks J; Aktas H; Chorev M; Halperin JA
    J Med Chem; 2004 Oct; 47(21):4979-82. PubMed ID: 15456240
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis, antitumour activity and structure-activity relationships of 5H-benzo[b]carbazoles.
    Asche C; Frank W; Albert A; Kucklaender U
    Bioorg Med Chem; 2005 Feb; 13(3):819-37. PubMed ID: 15653349
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Syntheses and biological activities of rebeccamycin analogues with uncommon sugars.
    Zhang G; Shen J; Cheng H; Zhu L; Fang L; Luo S; Muller MT; Lee GE; Wei L; Du Y; Sun D; Wang PG
    J Med Chem; 2005 Apr; 48(7):2600-11. PubMed ID: 15801850
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure-activity relationships of indole compounds derived from combretastatin A4: synthesis and biological screening of 5-phenylpyrrolo[3,4-a]carbazole-1,3-diones as potential antivascular agents.
    Ty N; Dupeyre G; Chabot GG; Seguin J; Quentin L; Chiaroni A; Tillequin F; Scherman D; Michel S; Cachet X
    Eur J Med Chem; 2010 Sep; 45(9):3726-39. PubMed ID: 20538383
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis, and biological evaluation of pyrrolo[2,1-c][1,4]benzodiazepine and indole conjugates as anticancer agents.
    Wang JJ; Shen YK; Hu WP; Hsieh MC; Lin FL; Hsu MK; Hsu MH
    J Med Chem; 2006 Feb; 49(4):1442-9. PubMed ID: 16480280
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and biological evaluation of novel benzodioxinocarbazoles (BDCZs) as potential anticancer agents.
    Ayerbe N; Routier S; Gillaizeau I; Maiereanu C; Caignard DH; Pierré A; Léonce S; Coudert G
    Bioorg Med Chem Lett; 2010 Aug; 20(15):4670-4. PubMed ID: 20566289
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel prodrugs of tegafur that display improved anticancer activity and antiangiogenic properties.
    Engel D; Nudelman A; Tarasenko N; Levovich I; Makarovsky I; Sochotnikov S; Tarasenko I; Rephaeli A
    J Med Chem; 2008 Jan; 51(2):314-23. PubMed ID: 18163551
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Photochemical electrocyclisation of 3-vinylindoles to pyrido[2,3-a]-, pyrido[4,3-a]- and thieno[2,3-a]-carbazoles: design, synthesis, DNA binding and antitumor cell cytotoxicity.
    Lemster T; Pindur U; Lenglet G; Depauw S; Dassi C; David-Cordonnier MH
    Eur J Med Chem; 2009 Aug; 44(8):3235-52. PubMed ID: 19386396
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and anticancer activity of new 1-substituted-6H-pyrido[4,3-b]carbazole derivatives.
    Tylińska B; Jasztold-Howorko R; Mastalarz H; Szczaurska-Nowak K; Wietrzyk J
    Arch Pharm (Weinheim); 2008 Jun; 341(6):351-6. PubMed ID: 18404778
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.