BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

222 related articles for article (PubMed ID: 17602602)

  • 1. Synthesis, monoamine transporter binding, properties, and functional monoamine uptake activity of 3beta-[4-methylphenyl and 4-chlorophenyl]-2 beta-[5-(substituted phenyl)thiazol-2-yl]tropanes.
    Gong PK; Blough BE; Brieaddy LE; Huang X; Kuhar MJ; Navarro HA; Carroll FI
    J Med Chem; 2007 Jul; 50(15):3686-95. PubMed ID: 17602602
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Further studies on conformationally constrained tricyclic tropane analogues and their uptake inhibition at monoamine transporter sites: synthesis of (Z)-9-(substituted arylmethylene)-7-azatricyclo[4.3.1.0(3,7)]decanes as a novel class of serotonin transporter inhibitors.
    Zhang A; Zhou G; Hoepping A; Mukhopadhyaya J; Johnson KM; Zhang M; Kozikowski AP
    J Med Chem; 2002 Apr; 45(9):1930-41. PubMed ID: 11960503
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and monoamine transporter binding properties of 2beta-[3'-(substituted benzyl)isoxazol-5-yl]- and 2beta-[3'-methyl-4'-(substituted phenyl)isoxazol-5-yl]-3beta-(substituted phenyl)tropanes.
    Jin C; Navarro HA; Page K; Carroll FI
    Bioorg Med Chem; 2008 Jul; 16(14):6682-8. PubMed ID: 18556210
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 1-(4-Methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (Pyrovalerone) analogues: a promising class of monoamine uptake inhibitors.
    Meltzer PC; Butler D; Deschamps JR; Madras BK
    J Med Chem; 2006 Feb; 49(4):1420-32. PubMed ID: 16480278
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis, monoamine transporter binding properties, and behavioral pharmacology of a series of 3beta-(substituted phenyl)-2beta-(3'-substituted isoxazol-5-yl)tropanes.
    Carroll FI; Pawlush N; Kuhar MJ; Pollard GT; Howard JL
    J Med Chem; 2004 Jan; 47(2):296-302. PubMed ID: 14711303
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design and synthesis of promiscuous high-affinity monoamine transporter ligands: unraveling transporter selectivity.
    Greiner E; Boos TL; Prisinzano TE; De Martino MG; Zeglis B; Dersch CM; Marcus J; Partilla JS; Rothman RB; Jacobson AE; Rice KC
    J Med Chem; 2006 Mar; 49(5):1766-72. PubMed ID: 16509591
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and monoamine transporter binding properties of 2,3-diaryltropanes.
    Kotturi SV; Jiang S; Chang AC; Abraham P; Navarro HA; Kuhar MJ; Carroll FI
    J Med Chem; 2005 Nov; 48(23):7437-44. PubMed ID: 16279803
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure-activity relationships at monoamine transporters for a series of N-substituted 3alpha-(bis[4-fluorophenyl]methoxy)tropanes: comparative molecular field analysis, synthesis, and pharmacological evaluation.
    Kulkarni SS; Grundt P; Kopajtic T; Katz JL; Newman AH
    J Med Chem; 2004 Jun; 47(13):3388-98. PubMed ID: 15189035
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and biological properties of new 2beta-alkyl- and 2beta-aryl-3-(substituted phenyl)tropane derivatives: stereochemical effect of C-3 on affinity and selectivity for neuronal dopamine and serotonin transporters.
    Kozikowski AP; Araldi GL; Prakash KR; Zhang M; Johnson KM
    J Med Chem; 1998 Dec; 41(25):4973-82. PubMed ID: 9836615
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-activity relationship studies on a novel series of (S)-2beta-substituted 3alpha-[bis(4-fluoro- or 4-chlorophenyl)methoxy]tropane analogues for in vivo investigation.
    Zou MF; Cao J; Kopajtic T; Desai RI; Katz JL; Newman AH
    J Med Chem; 2006 Oct; 49(21):6391-9. PubMed ID: 17034144
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and receptor binding properties of 2beta-alkynyl and 2beta-(1,2,3-triazol)substituted 3beta-(substituted phenyl)tropane derivatives.
    Jin C; Navarro HA; Carroll FI
    Bioorg Med Chem; 2008 May; 16(10):5529-35. PubMed ID: 18434164
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Monoamine transporter binding, locomotor activity, and drug discrimination properties of 3-(4-substituted-phenyl)tropane-2-carboxylic acid methyl ester isomers.
    Carroll FI; Runyon SP; Abraham P; Navarro H; Kuhar MJ; Pollard GT; Howard JL
    J Med Chem; 2004 Dec; 47(25):6401-9. PubMed ID: 15566309
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and monoamine transporter affinity of new 2beta-carbomethoxy-3beta-[4-(substituted thiophenyl)]phenyltropanes: discovery of a selective SERT antagonist with picomolar potency.
    Tamagnan G; Alagille D; Fu X; Kula NS; Baldessarini RJ; Innis RB; Baldwin RM
    Bioorg Med Chem Lett; 2005 Feb; 15(4):1131-3. PubMed ID: 15686927
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 1-Heteroaryl-6-(3,4-dichlorophenyl)-3-azabicyclo[4.1.0]heptane: further insights into a class of triple re-uptake inhibitors.
    Micheli F; Cavanni P; Bettati M; Bonanomi G; Di Fabio R; Fazzolari E; Marchioro C; Roscic M; Tarsi L; Visentini F; Zonzini L; Worby A
    Bioorg Med Chem; 2011 Jun; 19(11):3451-61. PubMed ID: 21550808
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Biaryl analogues of conformationally constrained tricyclic tropanes as potent and selective norepinephrine reuptake inhibitors: synthesis and evaluation of their uptake inhibition at monoamine transporter sites.
    Zhou J; Zhang A; Kläss T; Johnson KM; Wang CZ; Ye YP; Kozikowski AP
    J Med Chem; 2003 May; 46(10):1997-2007. PubMed ID: 12723962
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pharmacological and behavioral characterization of D-473, an orally active triple reuptake inhibitor targeting dopamine, serotonin and norepinephrine transporters.
    Dutta AK; Santra S; Sharma H; Voshavar C; Xu L; Mabrouk O; Antonio T; Reith ME
    PLoS One; 2014; 9(11):e113420. PubMed ID: 25427177
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis of 2beta-acyl-3beta-(substituted naphthyl)-8-azabicyclo[3.2.1]octanes and their binding affinities at dopamine and serotonin transport sites.
    Davies HM; Gilliatt V; Kuhn LA; Saikali E; Ren P; Hammond PS; Sexton T; Childers SR
    J Med Chem; 2001 May; 44(10):1509-15. PubMed ID: 11334561
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An extended study of dimeric phenyl tropanes.
    Nielsen S; Pedersen CM; Hansen SG; Petersen MD; Sinning S; Wiborg O; Jensen HH; Bols M
    Bioorg Med Chem; 2009 Jul; 17(14):4900-9. PubMed ID: 19560930
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and biological evaluation of novel 3,4-diaryl lactam derivatives as triple reuptake inhibitors.
    Park JE; Song C; Choi K; Sim T; Moon B; Roh EJ
    Bioorg Med Chem Lett; 2013 Oct; 23(20):5515-8. PubMed ID: 24012181
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure-activity relationships at monoamine transporters and muscarinic receptors for N-substituted-3alpha-(3'-chloro-, 4'-chloro-, and 4',4''-dichloro-substituted-diphenyl)methoxytropanes.
    Newman AH; Robarge MJ; Howard IM; Wittkopp SL; George C; Kopajtic T; Izenwasser S; Katz JL
    J Med Chem; 2001 Feb; 44(4):633-40. PubMed ID: 11170654
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.