These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

213 related articles for article (PubMed ID: 17603074)

  • 1. Structure-based protocol for identifying mutations that enhance protein-protein binding affinities.
    Sammond DW; Eletr ZM; Purbeck C; Kimple RJ; Siderovski DP; Kuhlman B
    J Mol Biol; 2007 Aug; 371(5):1392-404. PubMed ID: 17603074
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Computational design of second-site suppressor mutations at protein-protein interfaces.
    Sammond DW; Eletr ZM; Purbeck C; Kuhlman B
    Proteins; 2010 Mar; 78(4):1055-65. PubMed ID: 19899154
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural determinants of affinity enhancement between GoLoco motifs and G-protein alpha subunit mutants.
    Bosch DE; Kimple AJ; Sammond DW; Muller RE; Miley MJ; Machius M; Kuhlman B; Willard FS; Siderovski DP
    J Biol Chem; 2011 Feb; 286(5):3351-8. PubMed ID: 21115486
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Guanine nucleotide dissociation inhibitor activity of the triple GoLoco motif protein G18: alanine-to-aspartate mutation restores function to an inactive second GoLoco motif.
    Kimple RJ; Willard FS; Hains MD; Jones MB; Nweke GK; Siderovski DP
    Biochem J; 2004 Mar; 378(Pt 3):801-8. PubMed ID: 14656218
    [TBL] [Abstract][Full Text] [Related]  

  • 5. G alpha selectivity and inhibitor function of the multiple GoLoco motif protein GPSM2/LGN.
    McCudden CR; Willard FS; Kimple RJ; Johnston CA; Hains MD; Jones MB; Siderovski DP
    Biochim Biophys Acta; 2005 Sep; 1745(2):254-64. PubMed ID: 15946753
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Sequence determinants of E2-E6AP binding affinity and specificity.
    Eletr ZM; Kuhlman B
    J Mol Biol; 2007 Jun; 369(2):419-28. PubMed ID: 17433363
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A Residue outside the Binding Site Determines the Gα Binding Specificity of GoLoco Motifs.
    Liu C; Weng J; Wang D; Yang M; Jia M; Wang W
    Biochemistry; 2018 Nov; 57(47):6562-6569. PubMed ID: 30406994
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural determinants for GoLoco-induced inhibition of nucleotide release by Galpha subunits.
    Kimple RJ; Kimple ME; Betts L; Sondek J; Siderovski DP
    Nature; 2002 Apr; 416(6883):878-81. PubMed ID: 11976690
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure of Galpha(i1) bound to a GDP-selective peptide provides insight into guanine nucleotide exchange.
    Johnston CA; Willard FS; Jezyk MR; Fredericks Z; Bodor ET; Jones MB; Blaesius R; Watts VJ; Harden TK; Sondek J; Ramer JK; Siderovski DP
    Structure; 2005 Jul; 13(7):1069-80. PubMed ID: 16004878
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Differential G-alpha interaction capacities of the GoLoco motifs in Rap GTPase activating proteins.
    Willard FS; Low AB; McCudden CR; Siderovski DP
    Cell Signal; 2007 Feb; 19(2):428-38. PubMed ID: 16949794
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
    Sundberg EJ; Urrutia M; Braden BC; Isern J; Tsuchiya D; Fields BA; Malchiodi EL; Tormo J; Schwarz FP; Mariuzza RA
    Biochemistry; 2000 Dec; 39(50):15375-87. PubMed ID: 11112523
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular dynamics-solvated interaction energy studies of protein-protein interactions: the MP1-p14 scaffolding complex.
    Cui Q; Sulea T; Schrag JD; Munger C; Hung MN; Naïm M; Cygler M; Purisima EO
    J Mol Biol; 2008 Jun; 379(4):787-802. PubMed ID: 18479705
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Protein-protein interactions: general trends in the relationship between binding affinity and interfacial buried surface area.
    Chen J; Sawyer N; Regan L
    Protein Sci; 2013 Apr; 22(4):510-5. PubMed ID: 23389845
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Computational design of the sequence and structure of a protein-binding peptide.
    Sammond DW; Bosch DE; Butterfoss GL; Purbeck C; Machius M; Siderovski DP; Kuhlman B
    J Am Chem Soc; 2011 Mar; 133(12):4190-2. PubMed ID: 21388199
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Computational structural analysis: multiple proteins bound to DNA.
    Tomovic A; Oakeley EJ
    PLoS One; 2008 Sep; 3(9):e3243. PubMed ID: 18802470
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Rapid Sampling of Hydrogen Bond Networks for Computational Protein Design.
    Maguire JB; Boyken SE; Baker D; Kuhlman B
    J Chem Theory Comput; 2018 May; 14(5):2751-2760. PubMed ID: 29652499
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The structural basis of the dominant negative phenotype of the Gαi1β1γ2 G203A/A326S heterotrimer.
    Liu P; Jia MZ; Zhou XE; De Waal PW; Dickson BM; Liu B; Hou L; Yin YT; Kang YY; Shi Y; Melcher K; Xu HE; Jiang Y
    Acta Pharmacol Sin; 2016 Sep; 37(9):1259-72. PubMed ID: 27498775
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effects of partial agonists and Mg2+ ions on the interaction of M2 muscarinic acetylcholine receptor and G protein Galpha i1 subunit in the M2-Galpha i1 fusion protein.
    Zhang Q; Okamura M; Guo ZD; Niwa S; Haga T
    J Biochem; 2004 May; 135(5):589-96. PubMed ID: 15173197
    [TBL] [Abstract][Full Text] [Related]  

  • 19. D2 dopamine receptor activation of potassium channels is selectively decoupled by Galpha-specific GoLoco motif peptides.
    Webb CK; McCudden CR; Willard FS; Kimple RJ; Siderovski DP; Oxford GS
    J Neurochem; 2005 Mar; 92(6):1408-18. PubMed ID: 15748159
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutation of cysteine 214 in Gi1 alpha subunit abolishes its endogenous GTPase activity.
    Wang Y; Tawa G; Smith D; Krishnamurthy G; Young KH
    Biochem J; 2004 May; 379(Pt 3):673-9. PubMed ID: 14725508
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.