329 related articles for article (PubMed ID: 17606614)
1. Galphaq directly activates p63RhoGEF and Trio via a conserved extension of the Dbl homology-associated pleckstrin homology domain.
Rojas RJ; Yohe ME; Gershburg S; Kawano T; Kozasa T; Sondek J
J Biol Chem; 2007 Oct; 282(40):29201-10. PubMed ID: 17606614
[TBL] [Abstract][Full Text] [Related]
2. Structure of Galphaq-p63RhoGEF-RhoA complex reveals a pathway for the activation of RhoA by GPCRs.
Lutz S; Shankaranarayanan A; Coco C; Ridilla M; Nance MR; Vettel C; Baltus D; Evelyn CR; Neubig RR; Wieland T; Tesmer JJ
Science; 2007 Dec; 318(5858):1923-7. PubMed ID: 18096806
[TBL] [Abstract][Full Text] [Related]
3. Galpha q allosterically activates and relieves autoinhibition of p63RhoGEF.
Shankaranarayanan A; Boguth CA; Lutz S; Vettel C; Uhlemann F; Aittaleb M; Wieland T; Tesmer JJ
Cell Signal; 2010 Jul; 22(7):1114-23. PubMed ID: 20214977
[TBL] [Abstract][Full Text] [Related]
4. The RhoA-specific guanine nucleotide exchange factor p63RhoGEF binds to activated Galpha(16) and inhibits the canonical phospholipase Cbeta pathway.
Yeung WW; Wong YH
Cell Signal; 2009 Aug; 21(8):1317-25. PubMed ID: 19332116
[TBL] [Abstract][Full Text] [Related]
5. p63RhoGEF couples Gα(q/11)-mediated signaling to Ca2+ sensitization of vascular smooth muscle contractility.
Momotani K; Artamonov MV; Utepbergenov D; Derewenda U; Derewenda ZS; Somlyo AV
Circ Res; 2011 Oct; 109(9):993-1002. PubMed ID: 21885830
[TBL] [Abstract][Full Text] [Related]
6. Structure of the C-terminal guanine nucleotide exchange factor module of Trio in an autoinhibited conformation reveals its oncogenic potential.
Bandekar SJ; Arang N; Tully ES; Tang BA; Barton BL; Li S; Gutkind JS; Tesmer JJG
Sci Signal; 2019 Feb; 12(569):. PubMed ID: 30783010
[TBL] [Abstract][Full Text] [Related]
7. Trio's Rho-specific GEF domain is the missing Galpha q effector in C. elegans.
Williams SL; Lutz S; Charlie NK; Vettel C; Ailion M; Coco C; Tesmer JJ; Jorgensen EM; Wieland T; Miller KG
Genes Dev; 2007 Nov; 21(21):2731-46. PubMed ID: 17942708
[TBL] [Abstract][Full Text] [Related]
8. Galpha13 regulation of proto-Dbl signaling.
Vanni C; Mancini P; Ottaviano C; Ognibene M; Parodi A; Merello E; Russo C; Varesio L; Zheng Y; Torrisi MR; Eva A
Cell Cycle; 2007 Aug; 6(16):2058-70. PubMed ID: 17721084
[TBL] [Abstract][Full Text] [Related]
9. LARG links histamine-H1-receptor-activated Gq to Rho-GTPase-dependent signaling pathways.
Pfreimer M; Vatter P; Langer T; Wieland T; Gierschik P; Moepps B
Cell Signal; 2012 Mar; 24(3):652-63. PubMed ID: 22100544
[TBL] [Abstract][Full Text] [Related]
10. Activation of p115-RhoGEF requires direct association of Gα13 and the Dbl homology domain.
Chen Z; Guo L; Hadas J; Gutowski S; Sprang SR; Sternweis PC
J Biol Chem; 2012 Jul; 287(30):25490-500. PubMed ID: 22661716
[TBL] [Abstract][Full Text] [Related]
11. Plasma membrane association of p63 Rho guanine nucleotide exchange factor (p63RhoGEF) is mediated by palmitoylation and is required for basal activity in cells.
Aittaleb M; Nishimura A; Linder ME; Tesmer JJ
J Biol Chem; 2011 Sep; 286(39):34448-56. PubMed ID: 21832057
[TBL] [Abstract][Full Text] [Related]
12. Leukemia-associated Rho guanine nucleotide exchange factor promotes G alpha q-coupled activation of RhoA.
Booden MA; Siderovski DP; Der CJ
Mol Cell Biol; 2002 Jun; 22(12):4053-61. PubMed ID: 12024019
[TBL] [Abstract][Full Text] [Related]
13. The DH and PH domains of Trio coordinately engage Rho GTPases for their efficient activation.
Chhatriwala MK; Betts L; Worthylake DK; Sondek J
J Mol Biol; 2007 May; 368(5):1307-20. PubMed ID: 17391702
[TBL] [Abstract][Full Text] [Related]
14. Mechanisms for reversible regulation between G13 and Rho exchange factors.
Wells CD; Liu MY; Jackson M; Gutowski S; Sternweis PM; Rothstein JD; Kozasa T; Sternweis PC
J Biol Chem; 2002 Jan; 277(2):1174-81. PubMed ID: 11698392
[TBL] [Abstract][Full Text] [Related]
15. Mechanisms of guanine nucleotide exchange and Rac-mediated signaling revealed by a dominant negative trio mutant.
Debreceni B; Gao Y; Guo F; Zhu K; Jia B; Zheng Y
J Biol Chem; 2004 Jan; 279(5):3777-86. PubMed ID: 14597635
[TBL] [Abstract][Full Text] [Related]
16. Structural determinants of RhoA binding and nucleotide exchange in leukemia-associated Rho guanine-nucleotide exchange factor.
Kristelly R; Gao G; Tesmer JJ
J Biol Chem; 2004 Nov; 279(45):47352-62. PubMed ID: 15331592
[TBL] [Abstract][Full Text] [Related]
17. Signaling efficiency of Gαq through its effectors p63RhoGEF and GEFT depends on their subcellular location.
Goedhart J; van Unen J; Adjobo-Hermans MJ; Gadella TW
Sci Rep; 2013; 3():2284. PubMed ID: 23884432
[TBL] [Abstract][Full Text] [Related]
18. Human p63RhoGEF, a novel RhoA-specific guanine nucleotide exchange factor, is localized in cardiac sarcomere.
Souchet M; Portales-Casamar E; Mazurais D; Schmidt S; Léger I; Javré JL; Robert P; Berrebi-Bertrand I; Bril A; Gout B; Debant A; Calmels TP
J Cell Sci; 2002 Feb; 115(Pt 3):629-40. PubMed ID: 11861769
[TBL] [Abstract][Full Text] [Related]
19. Insights into the molecular activation mechanism of the RhoA-specific guanine nucleotide exchange factor, PDZRhoGEF.
Bielnicki JA; Shkumatov AV; Derewenda U; Somlyo AV; Svergun DI; Derewenda ZS
J Biol Chem; 2011 Oct; 286(40):35163-75. PubMed ID: 21816819
[TBL] [Abstract][Full Text] [Related]
20. NMR structure and mutagenesis of the N-terminal Dbl homology domain of the nucleotide exchange factor Trio.
Liu X; Wang H; Eberstadt M; Schnuchel A; Olejniczak ET; Meadows RP; Schkeryantz JM; Janowick DA; Harlan JE; Harris EA; Staunton DE; Fesik SW
Cell; 1998 Oct; 95(2):269-77. PubMed ID: 9790533
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
