103 related articles for article (PubMed ID: 17610913)
1. Activation of ERG2 potassium channels by the diphenylurea NS1643.
Elmedyb P; Olesen SP; Grunnet M
Neuropharmacology; 2007 Aug; 53(2):283-94. PubMed ID: 17610913
[TBL] [Abstract][Full Text] [Related]
2. Activation of human ether-a-go-go-related gene potassium channels by the diphenylurea 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643).
Hansen RS; Diness TG; Christ T; Demnitz J; Ravens U; Olesen SP; Grunnet M
Mol Pharmacol; 2006 Jan; 69(1):266-77. PubMed ID: 16219910
[TBL] [Abstract][Full Text] [Related]
3. Strong activation of ether-à-go-go-related gene 1 K+ channel isoforms by NS1643 in human embryonic kidney 293 and Chinese hamster ovary cells.
Schuster AM; Glassmeier G; Bauer CK
Mol Pharmacol; 2011 Nov; 80(5):930-42. PubMed ID: 21856740
[TBL] [Abstract][Full Text] [Related]
4. Differential effects of Kv11.1 activators on Kv11.1a, Kv11.1b and Kv11.1a/Kv11.1b channels.
Larsen AP; Bentzen BH; Grunnet M
Br J Pharmacol; 2010 Oct; 161(3):614-28. PubMed ID: 20880400
[TBL] [Abstract][Full Text] [Related]
5. NS1643 interacts around L529 of hERG to alter voltage sensor movement on the path to activation.
Guo J; Cheng YM; Lees-Miller JP; Perissinotti LL; Claydon TW; Hull CM; Thouta S; Roach DE; Durdagi S; Noskov SY; Duff HJ
Biophys J; 2015 Mar; 108(6):1400-1413. PubMed ID: 25809253
[TBL] [Abstract][Full Text] [Related]
6. Potent activation of large-conductance Ca2+-activated K+ channels by the diphenylurea 1,3-bis-[2-hydroxy-5-(trifluoromethyl)phenyl]urea (NS1643) in pituitary tumor (GH3) cells.
Wu SN; Peng H; Chen BS; Wang YJ; Wu PY; Lin MW
Mol Pharmacol; 2008 Dec; 74(6):1696-704. PubMed ID: 18809671
[TBL] [Abstract][Full Text] [Related]
7. Mechanism of action of a novel human ether-a-go-go-related gene channel activator.
Casis O; Olesen SP; Sanguinetti MC
Mol Pharmacol; 2006 Feb; 69(2):658-65. PubMed ID: 16284303
[TBL] [Abstract][Full Text] [Related]
8. Structure-guided topographic mapping and mutagenesis to elucidate binding sites for the human ether-a-go-go-related gene 1 potassium channel (KCNH2) activator NS1643.
Durdagi S; Guo J; Lees-Miller JP; Noskov SY; Duff HJ
J Pharmacol Exp Ther; 2012 Aug; 342(2):441-52. PubMed ID: 22573844
[TBL] [Abstract][Full Text] [Related]
9. Effects of the small molecule HERG activator NS1643 on Kv11.3 channels.
Bilet A; Bauer CK
PLoS One; 2012; 7(11):e50886. PubMed ID: 23226420
[TBL] [Abstract][Full Text] [Related]
10. Loss of functional K+ channels encoded by ether-à-go-go-related genes in mouse myometrium prior to labour onset.
Greenwood IA; Yeung SY; Tribe RM; Ohya S
J Physiol; 2009 May; 587(Pt 10):2313-26. PubMed ID: 19332483
[TBL] [Abstract][Full Text] [Related]
11. Kinetic model for NS1643 drug activation of WT and L529I variants of Kv11.1 (hERG1) potassium channel.
Perissinotti LL; Guo J; De Biase PM; Clancy CE; Duff HJ; Noskov SY
Biophys J; 2015 Mar; 108(6):1414-1424. PubMed ID: 25809254
[TBL] [Abstract][Full Text] [Related]
12. Molecular determinants of human ether-à-go-go-related gene 1 (hERG1) K+ channel activation by NS1643.
Grunnet M; Abbruzzese J; Sachse FB; Sanguinetti MC
Mol Pharmacol; 2011 Jan; 79(1):1-9. PubMed ID: 20876384
[TBL] [Abstract][Full Text] [Related]
13. Computational analysis of the effects of the hERG channel opener NS1643 in a human ventricular cell model.
Peitersen T; Grunnet M; Benson AP; Holden AV; Holstein-Rathlou NH; Olesen SP
Heart Rhythm; 2008 May; 5(5):734-41. PubMed ID: 18452879
[TBL] [Abstract][Full Text] [Related]
14. The human ether-a-go-go-related gene activator NS1643 enhances epilepsy-associated KCNQ channels.
Li P; Chen X; Zhang Q; Zheng Y; Jiang H; Yang H; Gao Z
J Pharmacol Exp Ther; 2014 Dec; 351(3):596-604. PubMed ID: 25232191
[TBL] [Abstract][Full Text] [Related]
15. NS1643 enhances ionic currents in a G604S-WT hERG co-expression system associated with long QT syndrome 2.
Huo J; Guo X; Lu Q; Qiang H; Liu P; Bai L; Huang CL; Zhang Y; Ma A
Clin Exp Pharmacol Physiol; 2017 Nov; 44(11):1125-1133. PubMed ID: 28741726
[TBL] [Abstract][Full Text] [Related]
16. Extracellular potassium effects are conserved within the rat erg K+ channel family.
Sturm P; Wimmers S; Schwarz JR; Bauer CK
J Physiol; 2005 Apr; 564(Pt 2):329-45. PubMed ID: 15705650
[TBL] [Abstract][Full Text] [Related]
17. Pharmacological activation of Kv11.1 in transgenic long QT-1 rabbits.
Bentzen BH; Bahrke S; Wu K; Larsen AP; Odening KE; Franke G; Storm vańs Gravesande K; Biermann J; Peng X; Koren G; Zehender M; Bode C; Grunnet M; Brunner M
J Cardiovasc Pharmacol; 2011 Feb; 57(2):223-30. PubMed ID: 21135701
[TBL] [Abstract][Full Text] [Related]
18. ERG Channels Regulate Excitability in Stellate and Bushy Cells of Mice Ventral Cochlear Nucleus.
Yildirim C; Bal R
J Membr Biol; 2018 Dec; 251(5-6):711-722. PubMed ID: 30206647
[TBL] [Abstract][Full Text] [Related]
19. Expression pattern of the ether-a-gogo-related (ERG) K+ channel-encoding genes ERG1, ERG2, and ERG3 in the adult rat central nervous system.
Papa M; Boscia F; Canitano A; Castaldo P; Sellitti S; Annunziato L; Taglialatela M
J Comp Neurol; 2003 Nov; 466(1):119-35. PubMed ID: 14515244
[TBL] [Abstract][Full Text] [Related]
20. C-Linker Accounts for Differential Sensitivity of ERG1 and ERG2 K+ Channels to RPR260243-Induced Slow Deactivation.
Gardner A; Sanguinetti MC
Mol Pharmacol; 2015 Jul; 88(1):19-28. PubMed ID: 25888115
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]