BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

94 related articles for article (PubMed ID: 17616684)

  • 1. Regulation of mammalian target of rapamycin activity in PTEN-inactive prostate cancer cells by I kappa B kinase alpha.
    Dan HC; Adli M; Baldwin AS
    Cancer Res; 2007 Jul; 67(13):6263-9. PubMed ID: 17616684
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mutations in the PI3K/PTEN/TSC2 pathway contribute to mammalian target of rapamycin activity and increased translation under hypoxic conditions.
    Kaper F; Dornhoefer N; Giaccia AJ
    Cancer Res; 2006 Feb; 66(3):1561-9. PubMed ID: 16452213
    [TBL] [Abstract][Full Text] [Related]  

  • 3. mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways.
    Majumder PK; Febbo PG; Bikoff R; Berger R; Xue Q; McMahon LM; Manola J; Brugarolas J; McDonnell TJ; Golub TR; Loda M; Lane HA; Sellers WR
    Nat Med; 2004 Jun; 10(6):594-601. PubMed ID: 15156201
    [TBL] [Abstract][Full Text] [Related]  

  • 4. AKT activity regulates the ability of mTOR inhibitors to prevent angiogenesis and VEGF expression in multiple myeloma cells.
    Frost P; Shi Y; Hoang B; Lichtenstein A
    Oncogene; 2007 Apr; 26(16):2255-62. PubMed ID: 17016437
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A cross-talk between the androgen receptor and the epidermal growth factor receptor leads to p38MAPK-dependent activation of mTOR and cyclinD1 expression in prostate and lung cancer cells.
    Recchia AG; Musti AM; Lanzino M; Panno ML; Turano E; Zumpano R; Belfiore A; Andò S; Maggiolini M
    Int J Biochem Cell Biol; 2009 Mar; 41(3):603-14. PubMed ID: 18692155
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Akt-dependent proapoptotic effects of dietary restriction on late-stage management of a phosphatase and tensin homologue/tuberous sclerosis complex 2-deficient mouse astrocytoma.
    Marsh J; Mukherjee P; Seyfried TN
    Clin Cancer Res; 2008 Dec; 14(23):7751-62. PubMed ID: 19047102
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Differential involvement of IkappaB kinases alpha and beta in cytokine- and insulin-induced mammalian target of rapamycin activation determined by Akt.
    Dan HC; Baldwin AS
    J Immunol; 2008 Jun; 180(11):7582-9. PubMed ID: 18490760
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Adiponectin signals in prostate cancer cells through Akt to activate the mammalian target of rapamycin pathway.
    Barb D; Neuwirth A; Mantzoros CS; Balk SP
    Endocr Relat Cancer; 2007 Dec; 14(4):995-1005. PubMed ID: 18045951
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Differential IKK/NF-κB Activity Is Mediated by TSC2 through mTORC1 in PTEN-Null Prostate Cancer and Tuberous Sclerosis Complex Tumor Cells.
    Gao Y; Gartenhaus RB; Lapidus RG; Hussain A; Zhang Y; Wang X; Dan HC
    Mol Cancer Res; 2015 Dec; 13(12):1602-14. PubMed ID: 26374334
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Silencing mammalian target of rapamycin signaling by small interfering RNA enhances rapamycin-induced autophagy in malignant glioma cells.
    Iwamaru A; Kondo Y; Iwado E; Aoki H; Fujiwara K; Yokoyama T; Mills GB; Kondo S
    Oncogene; 2007 Mar; 26(13):1840-51. PubMed ID: 17001313
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mammalian target of rapamycin activation impairs hepatocytic differentiation and targets genes moderating lipid homeostasis and hepatocellular growth.
    Parent R; Kolippakkam D; Booth G; Beretta L
    Cancer Res; 2007 May; 67(9):4337-45. PubMed ID: 17483347
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Osteoblasts-derived BMP-2 enhances the motility of prostate cancer cells via activation of integrins.
    Lai TH; Fong YC; Fu WM; Yang RS; Tang CH
    Prostate; 2008 Sep; 68(12):1341-53. PubMed ID: 18512729
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A hierarchical cascade activated by non-canonical Notch signaling and the mTOR-Rictor complex regulates neglect-induced death in mammalian cells.
    Perumalsamy LR; Nagala M; Banerjee P; Sarin A
    Cell Death Differ; 2009 Jun; 16(6):879-89. PubMed ID: 19265851
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 9-Aminoacridine-based anticancer drugs target the PI3K/AKT/mTOR, NF-kappaB and p53 pathways.
    Guo C; Gasparian AV; Zhuang Z; Bosykh DA; Komar AA; Gudkov AV; Gurova KV
    Oncogene; 2009 Feb; 28(8):1151-61. PubMed ID: 19137016
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas.
    Hernando E; Charytonowicz E; Dudas ME; Menendez S; Matushansky I; Mills J; Socci ND; Behrendt N; Ma L; Maki RG; Pandolfi PP; Cordon-Cardo C
    Nat Med; 2007 Jun; 13(6):748-53. PubMed ID: 17496901
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Akt activation protects pancreatic beta cells from AMPK-mediated death through stimulation of mTOR.
    Cai Y; Wang Q; Ling Z; Pipeleers D; McDermott P; Pende M; Heimberg H; Van de Casteele M
    Biochem Pharmacol; 2008 May; 75(10):1981-93. PubMed ID: 18377870
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The protein phosphatase activity of PTEN regulates SRC family kinases and controls glioma migration.
    Dey N; Crosswell HE; De P; Parsons R; Peng Q; Su JD; Durden DL
    Cancer Res; 2008 Mar; 68(6):1862-71. PubMed ID: 18339867
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Akt-dependent regulation of NF-{kappa}B is controlled by mTOR and Raptor in association with IKK.
    Dan HC; Cooper MJ; Cogswell PC; Duncan JA; Ting JP; Baldwin AS
    Genes Dev; 2008 Jun; 22(11):1490-500. PubMed ID: 18519641
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A gene transcription signature of the Akt/mTOR pathway in clinical breast tumors.
    Creighton CJ
    Oncogene; 2007 Jul; 26(32):4648-55. PubMed ID: 17213801
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Unsaturated fatty acids inhibit the expression of tumor suppressor phosphatase and tensin homolog (PTEN) via microRNA-21 up-regulation in hepatocytes.
    Vinciguerra M; Sgroi A; Veyrat-Durebex C; Rubbia-Brandt L; Buhler LH; Foti M
    Hepatology; 2009 Apr; 49(4):1176-84. PubMed ID: 19072831
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.