BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

136 related articles for article (PubMed ID: 17620380)

  • 1. In vitro suppression of K65R reverse transcriptase-mediated tenofovir- and adefovir-5'-diphosphate resistance conferred by the boranophosphonate derivatives.
    Frangeul A; Barral K; Alvarez K; Canard B
    Antimicrob Agents Chemother; 2007 Sep; 51(9):3162-7. PubMed ID: 17620380
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and substrate properties towards HIV-1 reverse transcriptase of new diphosphate analogues of 9-[(2-phosphonomethoxy)ethyl]adenine.
    Laux WH; Priet S; Alvarez K; Peyrottes S; Périgaud C
    Antivir Chem Chemother; 2018; 26():2040206618757636. PubMed ID: 29436843
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Virologic and enzymatic studies revealing the mechanism of K65R- and Q151M-associated HIV-1 drug resistance towards emtricitabine and lamivudine.
    Feng JY; Myrick FT; Margot NA; Mulamba GB; Rimsky L; Borroto-Esoda K; Selmi B; Canard B
    Nucleosides Nucleotides Nucleic Acids; 2006; 25(1):89-107. PubMed ID: 16440988
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Borano-nucleotides: new analogues to circumvent HIV-1 RT-mediated nucleoside drug-resistance.
    Alvarez K; Deval J; Selmi B; Barral K; Boretto J; Guerreiro C; Mulard L; Sarfati R; Canard B
    Nucleosides Nucleotides Nucleic Acids; 2005; 24(5-7):419-21. PubMed ID: 16247962
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Gln151 of HIV-1 reverse transcriptase acts as a steric gate towards clinically relevant acyclic phosphonate nucleotide analogues.
    Frangeul A; Bussetta C; Deval J; Barral K; Alvarez K; Canard B
    Antivir Ther; 2008; 13(1):115-24. PubMed ID: 18389906
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pre-steady state kinetic analysis of cyclobutyl derivatives of 2'-deoxyadenosine 5'-triphosphate as inhibitors of HIV-1 reverse transcriptase.
    Kim J; Wang L; Li Y; Becnel KD; Frey KM; Garforth SJ; Prasad VR; Schinazi RF; Liotta DC; Anderson KS
    Bioorg Med Chem Lett; 2012 Jun; 22(12):4064-7. PubMed ID: 22595174
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular mechanisms of tenofovir resistance conferred by human immunodeficiency virus type 1 reverse transcriptase containing a diserine insertion after residue 69 and multiple thymidine analog-associated mutations.
    White KL; Chen JM; Margot NA; Wrin T; Petropoulos CJ; Naeger LK; Swaminathan S; Miller MD
    Antimicrob Agents Chemother; 2004 Mar; 48(3):992-1003. PubMed ID: 14982794
    [TBL] [Abstract][Full Text] [Related]  

  • 8. K65R, TAMs and tenofovir.
    Miller MD
    AIDS Rev; 2004; 6(1):22-33. PubMed ID: 15168738
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Enzymatic synthesis of acyclic nucleoside thiophosphonate diphosphates: effect of the α-phosphorus configuration on HIV-1 RT activity.
    Priet S; Roux L; Saez-Ayala M; Ferron F; Canard B; Alvarez K
    Antiviral Res; 2015 May; 117():122-31. PubMed ID: 25766862
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Selective inhibition of HIV-1 reverse transcriptase by an antiviral inhibitor, (R)-9-(2-Phosphonylmethoxypropyl)adenine.
    Suo Z; Johnson KA
    J Biol Chem; 1998 Oct; 273(42):27250-8. PubMed ID: 9765248
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Molecular basis of antagonism between K70E and K65R tenofovir-associated mutations in HIV-1 reverse transcriptase.
    Kagan RM; Lee TS; Ross L; Lloyd RM; Lewinski MA; Potts SJ
    Antiviral Res; 2007 Sep; 75(3):210-8. PubMed ID: 17442410
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural basis for activation of alpha-boranophosphate nucleotide analogues targeting drug-resistant reverse transcriptase.
    Meyer P; Schneider B; Sarfati S; Deville-Bonne D; Guerreiro C; Boretto J; Janin J; Véron M; Canard B
    EMBO J; 2000 Jul; 19(14):3520-9. PubMed ID: 10899107
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The A62V and S68G mutations in HIV-1 reverse transcriptase partially restore the replication defect associated with the K65R mutation.
    Svarovskaia ES; Feng JY; Margot NA; Myrick F; Goodman D; Ly JK; White KL; Kutty N; Wang R; Borroto-Esoda K; Miller MD
    J Acquir Immune Defic Syndr; 2008 Aug; 48(4):428-36. PubMed ID: 18614922
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural basis for the role of the K65R mutation in HIV-1 reverse transcriptase polymerization, excision antagonism, and tenofovir resistance.
    Das K; Bandwar RP; White KL; Feng JY; Sarafianos SG; Tuske S; Tu X; Clark AD; Boyer PL; Hou X; Gaffney BL; Jones RA; Miller MD; Hughes SH; Arnold E
    J Biol Chem; 2009 Dec; 284(50):35092-100. PubMed ID: 19812032
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mechanisms of resistance to nucleoside analogue inhibitors of HIV-1 reverse transcriptase.
    Menéndez-Arias L
    Virus Res; 2008 Jun; 134(1-2):124-46. PubMed ID: 18272247
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis, in vitro antiviral evaluation, and stability studies of novel alpha-borano-nucleotide analogues of 9-[2-(phosphonomethoxy)ethyl]adenine and (R)-9-[2-(phosphonomethoxy)propyl]adenine.
    Barral K; Priet S; Sire J; Neyts J; Balzarini J; Canard B; Alvarez K
    J Med Chem; 2006 Dec; 49(26):7799-806. PubMed ID: 17181162
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Increasing prevalence of HIV-1 reverse transcriptase mutation K65R correlates with tenofovir utilization.
    Kagan RM; Merigan TC; Winters MA; Heseltine PN
    Antivir Ther; 2004 Oct; 9(5):827-8. PubMed ID: 15535422
    [No Abstract]   [Full Text] [Related]  

  • 18. Comparative enzymatic study of HIV-1 reverse transcriptase resistant to 2',3'-dideoxynucleotide analogs using the single-nucleotide incorporation assay.
    Ueno T; Mitsuya H
    Biochemistry; 1997 Feb; 36(5):1092-9. PubMed ID: 9033399
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The role of steric hindrance in 3TC resistance of human immunodeficiency virus type-1 reverse transcriptase.
    Gao HQ; Boyer PL; Sarafianos SG; Arnold E; Hughes SH
    J Mol Biol; 2000 Jul; 300(2):403-18. PubMed ID: 10873473
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effects of the translocation status of human immunodeficiency virus type 1 reverse transcriptase on the efficiency of excision of tenofovir.
    Marchand B; White KL; Ly JK; Margot NA; Wang R; McDermott M; Miller MD; Götte M
    Antimicrob Agents Chemother; 2007 Aug; 51(8):2911-9. PubMed ID: 17517852
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.