These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

105 related articles for article (PubMed ID: 1762475)

  • 21. Constraints on the sequence diversity of the protease of human immunodeficiency virus type 1: a guide for drug design.
    Kaplan AH
    AIDS Res Hum Retroviruses; 1996 Jul; 12(10):849-53. PubMed ID: 8798968
    [No Abstract]   [Full Text] [Related]  

  • 22. Design of novel HIV-1 protease inhibitors incorporating isophthalamide-derived P2-P3 ligands: Synthesis, biological evaluation and X-ray structural studies of inhibitor-HIV-1 protease complex.
    Ghosh AK; Brindisi M; Nyalapatla PR; Takayama J; Ella-Menye JR; Yashchuk S; Agniswamy J; Wang YF; Aoki M; Amano M; Weber IT; Mitsuya H
    Bioorg Med Chem; 2017 Oct; 25(19):5114-5127. PubMed ID: 28434781
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Recent developments of peptidomimetic HIV-1 protease inhibitors.
    Qiu X; Liu ZP
    Curr Med Chem; 2011; 18(29):4513-37. PubMed ID: 21864279
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Structure based design: novel spirocyclic ethers as nonpeptidal P2-ligands for HIV protease inhibitors.
    Ghosh AK; Krishnan K; Walters DE; Cho W; Cho H; Koo Y; Trevino J; Holland L; Buthod J
    Bioorg Med Chem Lett; 1998 Apr; 8(8):979-82. PubMed ID: 9871524
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Competitive inhibition of HIV-1 protease by biphenyl carboxylic acids.
    Tummino PJ; Ferguson D; Jacobs CM; Tait B; Hupe L; Lunney E; Hupe D
    Arch Biochem Biophys; 1995 Jan; 316(1):523-8. PubMed ID: 7840661
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Structure-based design, synthesis, X-ray studies, and biological evaluation of novel HIV-1 protease inhibitors containing isophthalamide-derived P2-ligands.
    Ghosh AK; Takayama J; Kassekert LA; Ella-Menye JR; Yashchuk S; Agniswamy J; Wang YF; Aoki M; Amano M; Weber IT; Mitsuya H
    Bioorg Med Chem Lett; 2015 Nov; 25(21):4903-4909. PubMed ID: 26096678
    [TBL] [Abstract][Full Text] [Related]  

  • 27. The not-so-great escape.
    Erickson JW
    Nat Struct Biol; 1995 Jul; 2(7):523-9. PubMed ID: 7664118
    [No Abstract]   [Full Text] [Related]  

  • 28. Design of symmetry-based, peptidomimetic inhibitors of human immunodeficiency virus protease.
    Kempf DJ
    Methods Enzymol; 1994; 241():334-54. PubMed ID: 7854187
    [No Abstract]   [Full Text] [Related]  

  • 29. HIV protease inhibitors: peptidomimetic drugs and future perspectives.
    Abdel-Rahman HM; Al-karamany GS; El-Koussi NA; Youssef AF; Kiso Y
    Curr Med Chem; 2002 Nov; 9(21):1905-22. PubMed ID: 12369875
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Design and synthesis of HIV-1 protease inhibitors. Novel tetrahydrofuran P2/P2'-groups interacting with Asp29/30 of the HIV-1 protease. Determination of binding from X-ray crystal structure of inhibitor protease complex.
    Oscarsson K; Lahmann M; Lindberg J; Kangasmetsä J; Unge T; Oscarson S; Hallberg A; Samuelsson B
    Bioorg Med Chem; 2003 Mar; 11(6):1107-15. PubMed ID: 12614898
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Structure-based design of sulfonamide-substituted non-peptidic HIV protease inhibitors.
    Skulnick HI; Johnson PD; Howe WJ; Tomich PK; Chong KT; Watenpaugh KD; Janakiraman MN; Dolak LA; McGrath JP; Lynn JC
    J Med Chem; 1995 Dec; 38(26):4968-71. PubMed ID: 8544171
    [No Abstract]   [Full Text] [Related]  

  • 32. Targeting dynamic pockets of HIV-1 protease by structure-based computational screening for allosteric inhibitors.
    Kunze J; Todoroff N; Schneider P; Rodrigues T; Geppert T; Reisen F; Schreuder H; Saas J; Hessler G; Baringhaus KH; Schneider G
    J Chem Inf Model; 2014 Mar; 54(3):987-91. PubMed ID: 24528206
    [TBL] [Abstract][Full Text] [Related]  

  • 33. HIV protease inhibitors.
    Winslow DL; Otto MJ
    AIDS; 1995; 9 Suppl A():S183-92. PubMed ID: 8819585
    [No Abstract]   [Full Text] [Related]  

  • 34. Identifying the molecular mechanics and binding dynamics characteristics of potent inhibitors to HIV-1 protease.
    Li D; Liu MS; Ji B; Hwang KC; Huang Y
    Chem Biol Drug Des; 2012 Sep; 80(3):440-54. PubMed ID: 22621379
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Design and synthesis of potent HIV-1 protease inhibitors incorporating hydroxyprolinamides as novel P2 ligands.
    Gao BL; Zhang CM; Yin YZ; Tang LQ; Liu ZP
    Bioorg Med Chem Lett; 2011 Jun; 21(12):3730-3. PubMed ID: 21555220
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Estimation of binding free energies for HIV proteinase inhibitors by molecular dynamics simulations.
    Hansson T; Aqvist J
    Protein Eng; 1995 Nov; 8(11):1137-44. PubMed ID: 8819979
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Structure-based design of HIV protease inhibitors: 4-hydroxycoumarins and 4-hydroxy-2-pyrones as non-peptidic inhibitors.
    Thaisrivongs S; Tomich PK; Watenpaugh KD; Chong KT; Howe WJ; Yang CP; Strohbach JW; Turner SR; McGrath JP; Bohanon MJ
    J Med Chem; 1994 Sep; 37(20):3200-4. PubMed ID: 7932546
    [No Abstract]   [Full Text] [Related]  

  • 38. Design, synthesis, and resistance patterns of MP-134 and MP-167, two novel inhibitors of HIV type 1 protease.
    Mo H; Markowitz M; Majer P; Burt SK; Gulnik SV; Suvorov LI; Erickson JW; Ho DD
    AIDS Res Hum Retroviruses; 1996 Jan; 12(1):55-61. PubMed ID: 8825619
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Molecular dynamics simulations applied to the study of subtypes of HIV-1 protease common to Brazil, Africa, and Asia.
    Batista PR; Wilter A; Durham EH; Pascutti PG
    Cell Biochem Biophys; 2006; 44(3):395-404. PubMed ID: 16679526
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Ligand design package (Ludi--MSI) applied to known inhibitors of the HIV-1 protease. Test of performance.
    Bogacewicz R; Trylska J; Geller M
    Acta Pol Pharm; 2000 Nov; 57 Suppl():25-8. PubMed ID: 11293255
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.