BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

637 related articles for article (PubMed ID: 17628016)

  • 1. Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma.
    Bar EE; Chaudhry A; Lin A; Fan X; Schreck K; Matsui W; Piccirillo S; Vescovi AL; DiMeco F; Olivi A; Eberhart CG
    Stem Cells; 2007 Oct; 25(10):2524-33. PubMed ID: 17628016
    [TBL] [Abstract][Full Text] [Related]  

  • 2. In vitro and in vivo characterization of a novel Hedgehog signaling antagonist in human glioblastoma cell lines.
    Ferruzzi P; Mennillo F; De Rosa A; Giordano C; Rossi M; Benedetti G; Magrini R; Pericot Mohr Gl; Miragliotta V; Magnoni L; Mori E; Thomas R; Tunici P; Bakker A
    Int J Cancer; 2012 Jul; 131(2):E33-44. PubMed ID: 22072503
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Notch target Hes1 directly modulates Gli1 expression and Hedgehog signaling: a potential mechanism of therapeutic resistance.
    Schreck KC; Taylor P; Marchionni L; Gopalakrishnan V; Bar EE; Gaiano N; Eberhart CG
    Clin Cancer Res; 2010 Dec; 16(24):6060-70. PubMed ID: 21169257
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Modulation of Sonic hedgehog signaling and WW domain containing oxidoreductase WOX1 expression enhances radiosensitivity of human glioblastoma cells.
    Chiang MF; Chen HH; Chi CW; Sze CI; Hsu ML; Shieh HR; Lin CP; Tsai JT; Chen YJ
    Exp Biol Med (Maywood); 2015 Mar; 240(3):392-9. PubMed ID: 25595187
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of the sonic hedgehog pathway by cyplopamine reduces the CD133+/CD15+ cell compartment and the in vitro tumorigenic capability of neuroblastoma cells.
    Schiapparelli P; Shahi MH; Enguita-Germán M; Johnsen JI; Kogner P; Lázcoz P; Castresana JS
    Cancer Lett; 2011 Nov; 310(2):222-31. PubMed ID: 21803487
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hedgehog signaling in glioblastoma multiforme.
    Braun S; Oppermann H; Mueller A; Renner C; Hovhannisyan A; Baran-Schmidt R; Gebhardt R; Hipkiss A; Thiery J; Meixensberger J; Gaunitz F
    Cancer Biol Ther; 2012 May; 13(7):487-95. PubMed ID: 22406999
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sonic Hedgehog inhibition as a strategy to augment radiosensitivity of hepatocellular carcinoma.
    Tsai CL; Hsu FM; Tzen KY; Liu WL; Cheng AL; Cheng JC
    J Gastroenterol Hepatol; 2015 Aug; 30(8):1317-24. PubMed ID: 25682950
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cyclopamine sensitizes glioblastoma cells to temozolomide treatment through Sonic hedgehog pathway.
    Carballo GB; Matias D; Ribeiro JH; Pessoa LS; Arrais-Neto AM; Spohr TCLSE
    Life Sci; 2020 Sep; 257():118027. PubMed ID: 32622951
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hedgehog signaling in small-cell lung cancer: frequent in vivo but a rare event in vitro.
    Vestergaard J; Pedersen MW; Pedersen N; Ensinger C; Tümer Z; Tommerup N; Poulsen HS; Larsen LA
    Lung Cancer; 2006 Jun; 52(3):281-90. PubMed ID: 16616798
    [TBL] [Abstract][Full Text] [Related]  

  • 10. HDAC6 inhibition induces glioma stem cells differentiation and enhances cellular radiation sensitivity through the SHH/Gli1 signaling pathway.
    Yang W; Liu Y; Gao R; Yu H; Sun T
    Cancer Lett; 2018 Feb; 415():164-176. PubMed ID: 29222038
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of hedgehog signaling attenuates carcinogenesis in vitro and increases necrosis of cholangiocellular carcinoma.
    El Khatib M; Kalnytska A; Palagani V; Kossatz U; Manns MP; Malek NP; Wilkens L; Plentz RR
    Hepatology; 2013 Mar; 57(3):1035-45. PubMed ID: 23172661
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Selective release of a cyclopamine glucuronide prodrug toward stem-like cancer cell inhibition in glioblastoma.
    Balbous A; Renoux B; Cortes U; Milin S; Guilloteau K; Legigan T; Rivet P; Boissonnade O; Martin S; Tripiana C; Wager M; Bensadoun RJ; Papot S; Karayan-Tapon L
    Mol Cancer Ther; 2014 Sep; 13(9):2159-69. PubMed ID: 25053823
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The sonic hedgehog signaling pathway stimulates anaplastic thyroid cancer cell motility and invasiveness by activating Akt and c-Met.
    Williamson AJ; Doscas ME; Ye J; Heiden KB; Xing M; Li Y; Prinz RA; Xu X
    Oncotarget; 2016 Mar; 7(9):10472-85. PubMed ID: 26859575
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hedgehog signaling pathway is active in GBM with GLI1 mRNA expression showing a single continuous distribution rather than discrete high/low clusters.
    Chandra V; Das T; Gulati P; Biswas NK; Rote S; Chatterjee U; Ghosh SN; Deb S; Saha SK; Chowdhury AK; Ghosh S; Rudin CM; Mukherjee A; Basu A; Dhara S
    PLoS One; 2015; 10(3):e0116390. PubMed ID: 25775002
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Combination therapy with micellarized cyclopamine and temozolomide attenuate glioblastoma growth through Gli1 down-regulation.
    Liu YJ; Ma YC; Zhang WJ; Yang ZZ; Liang DS; Wu ZF; Qi XR
    Oncotarget; 2017 Jun; 8(26):42495-42509. PubMed ID: 28477008
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effect of Hedgehog Signaling Pathway Activation on Proliferation of High-Grade Gliomas.
    Cherepanov SA; Cherepanova KI; Grinenko NF; Antonova OM; Chekhonin VP
    Bull Exp Biol Med; 2016 Sep; 161(5):674-678. PubMed ID: 27709388
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Evaluation of cytotoxic properties of a cyclopamine glucuronide prodrug in rat glioblastoma cells and tumors.
    Bensalma S; Chadeneau C; Legigan T; Renoux B; Gaillard A; de Boisvilliers M; Pinet-Charvet C; Papot S; Muller JM
    J Mol Neurosci; 2015 Jan; 55(1):51-61. PubMed ID: 25280457
    [TBL] [Abstract][Full Text] [Related]  

  • 18. QKI deficiency maintains glioma stem cell stemness by activating the SHH/GLI1 signaling pathway.
    Han B; Wang R; Chen Y; Meng X; Wu P; Li Z; Duan C; Li Q; Li Y; Zhao S; Jiang C; Cai J
    Cell Oncol (Dordr); 2019 Dec; 42(6):801-813. PubMed ID: 31292920
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [The effects of Hedgehog-Gli 1 signaling pathway on proliferation and apoptosis of hepatic stellate cells].
    Liu J; Xu XF; Yang WJ
    Zhonghua Gan Zang Bing Za Zhi; 2009 Jan; 17(1):33-7. PubMed ID: 19203449
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cyclopamine decreased the expression of Sonic Hedgehog and its downstream genes in colon cancer stem cells.
    Batsaikhan BE; Yoshikawa K; Kurita N; Iwata T; Takasu C; Kashihara H; Shimada M
    Anticancer Res; 2014 Nov; 34(11):6339-44. PubMed ID: 25368233
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 32.