BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

187 related articles for article (PubMed ID: 17628030)

  • 1. Synthesis, cleavage profile, and antitumor efficacy of an albumin-binding prodrug of methotrexate that is cleaved by plasmin and cathepsin B.
    Warnecke A; Fichtner I; Sass G; Kratz F
    Arch Pharm (Weinheim); 2007 Aug; 340(8):389-95. PubMed ID: 17628030
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Albumin-binding prodrugs of camptothecin and doxorubicin with an Ala-Leu-Ala-Leu-linker that are cleaved by cathepsin B: synthesis and antitumor efficacy.
    Schmid B; Chung DE; Warnecke A; Fichtner I; Kratz F
    Bioconjug Chem; 2007; 18(3):702-16. PubMed ID: 17378599
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeted drug delivery by in vivo coupling to endogenous albumin: an albumin-binding prodrug of methotrexate (MTX) is better than MTX in the treatment of murine collagen-induced arthritis.
    Fiehn C; Kratz F; Sass G; Müller-Ladner U; Neumann E
    Ann Rheum Dis; 2008 Aug; 67(8):1188-91. PubMed ID: 18408252
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Development of albumin-binding camptothecin prodrugs using a Peptide positional scanning library.
    Schmid B; Warnecke A; Fichtner I; Jung M; Kratz F
    Bioconjug Chem; 2007; 18(6):1786-99. PubMed ID: 17915955
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Development of albumin-binding doxorubicin prodrugs that are cleaved by prostate-specific antigen.
    Kratz F; Mansour A; Soltau J; Warnecke A; Fichtner I; Unger C; Drevs J
    Arch Pharm (Weinheim); 2005 Oct; 338(10):462-72. PubMed ID: 16211657
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In vitro and in vivo study of an albumin-binding prodrug of doxorubicin that is cleaved by cathepsin B.
    Abu Ajaj K; Graeser R; Fichtner I; Kratz F
    Cancer Chemother Pharmacol; 2009 Jul; 64(2):413-8. PubMed ID: 19229536
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Development of dual-acting prodrugs for circumventing multidrug resistance.
    Abu Ajaj K; Kratz F
    Bioorg Med Chem Lett; 2009 Feb; 19(3):995-1000. PubMed ID: 19131246
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and biological evaluation of an albumin-binding prodrug of doxorubicin that is cleaved by prostate-specific antigen (PSA) in a PSA-positive orthotopic prostate carcinoma model (LNCaP).
    Graeser R; Chung DE; Esser N; Moor S; Schächtele C; Unger C; Kratz F
    Int J Cancer; 2008 Mar; 122(5):1145-54. PubMed ID: 17973264
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Development of a novel albumin-binding prodrug that is cleaved by urokinase-type-plasminogen activator (uPA).
    Chung DE; Kratz F
    Bioorg Med Chem Lett; 2006 Oct; 16(19):5157-63. PubMed ID: 16875815
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and antitumor activity evaluations of albumin-binding prodrugs of CC-1065 analog.
    Wang Y; Jiang J; Jiang X; Cai S; Han H; Li L; Tian Z; Jiang W; Zhang Z; Xiao Y; Wright SC; Larrick JW
    Bioorg Med Chem; 2008 Jul; 16(13):6552-9. PubMed ID: 18508273
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Development of a novel prodrug of paclitaxel that is cleaved by prostate-specific antigen: an in vitro and in vivo evaluation study.
    Elsadek B; Graeser R; Esser N; Schäfer-Obodozie C; Abu Ajaj K; Unger C; Warnecke A; Saleem T; El-Melegy N; Madkor H; Kratz F
    Eur J Cancer; 2010 Dec; 46(18):3434-44. PubMed ID: 20933385
    [TBL] [Abstract][Full Text] [Related]  

  • 12. [The solid-phase synthesis of methotrexate-alpha-peptides].
    Shi PT; Hao XK; Chen Y; Zhang YH; Tao QY
    Yao Xue Xue Bao; 1997; 32(2):106-9. PubMed ID: 11243192
    [TBL] [Abstract][Full Text] [Related]  

  • 13. In vivo evaluation of a novel albumin-binding prodrug of doxorubicin in an orthotopic mouse model of prostate cancer (LNCaP).
    Elsadek B; Graeser R; Esser N; Schäfer-Obodozie C; Tsurumi C; Abu Ajaj K; Warnecke A; Unger C; Saleem T; Kratz F
    Prostate Cancer Prostatic Dis; 2011 Mar; 14(1):14-21. PubMed ID: 21042336
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The use of protein as a carrier of methotrexate for experimental cancer chemotherapy. III. Human serum albumin-methotrexate derivative, its preparation and basic testing.
    Bures L; Bostík J; Motycka K; Spundová M; Rehák L
    Neoplasma; 1988; 35(3):329-42. PubMed ID: 3405341
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Development of protein-binding bifunctional linkers for a new generation of dual-acting prodrugs.
    Abu Ajaj K; Biniossek ML; Kratz F
    Bioconjug Chem; 2009 Feb; 20(2):390-6. PubMed ID: 19199576
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A new approach for the treatment of malignant melanoma: enhanced antitumor efficacy of an albumin-binding doxorubicin prodrug that is cleaved by matrix metalloproteinase 2.
    Mansour AM; Drevs J; Esser N; Hamada FM; Badary OA; Unger C; Fichtner I; Kratz F
    Cancer Res; 2003 Jul; 63(14):4062-6. PubMed ID: 12874007
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Albumin as a drug carrier: design of prodrugs, drug conjugates and nanoparticles.
    Kratz F
    J Control Release; 2008 Dec; 132(3):171-83. PubMed ID: 18582981
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Methotrexate-alpha-phenylalanine: optimization of methotrexate prodrug for activation by carboxypeptidase A-monoclonal antibody conjugate.
    Vitols KS; Haag-Zeino B; Baer T; Montejano YD; Huennekens FM
    Cancer Res; 1995 Feb; 55(3):478-81. PubMed ID: 7834611
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The use of protein as a carrier of methotrexate for experimental cancer chemotherapy. V. Alternative method for preparation of serum albumin-methotrexate derivative.
    Bures L; Lichý A; Bostík J; Spundová M
    Neoplasma; 1990; 37(3):225-31. PubMed ID: 2370913
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Maleimide-oligo(ethylene glycol) derivatives of camptothecin as albumin-binding prodrugs: synthesis and antitumor efficacy.
    Warnecke A; Kratz F
    Bioconjug Chem; 2003; 14(2):377-87. PubMed ID: 12643748
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.