These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
752 related articles for article (PubMed ID: 17638894)
1. Breast cancer expressing the activated HER2/neu is sensitive to gefitinib in vitro and in vivo and acquires resistance through a novel point mutation in the HER2/neu. Piechocki MP; Yoo GH; Dibbley SK; Lonardo F Cancer Res; 2007 Jul; 67(14):6825-43. PubMed ID: 17638894 [TBL] [Abstract][Full Text] [Related]
2. HER2 overexpression increases sensitivity to gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor, through inhibition of HER2/HER3 heterodimer formation in lung cancer cells. Hirata A; Hosoi F; Miyagawa M; Ueda S; Naito S; Fujii T; Kuwano M; Ono M Cancer Res; 2005 May; 65(10):4253-60. PubMed ID: 15899817 [TBL] [Abstract][Full Text] [Related]
3. An update of the mechanisms of resistance to EGFR-tyrosine kinase inhibitors in breast cancer: Gefitinib (Iressa) -induced changes in the expression and nucleo-cytoplasmic trafficking of HER-ligands (Review). Ferrer-Soler L; Vazquez-Martin A; Brunet J; Menendez JA; De Llorens R; Colomer R Int J Mol Med; 2007 Jul; 20(1):3-10. PubMed ID: 17549382 [TBL] [Abstract][Full Text] [Related]
4. Iressa induces cytostasis and augments Fas-mediated apoptosis in acinic cell adenocarcinoma overexpressing HER2/neu. Piechocki MP; Yoo GH; Dibbley SK; Amjad EH; Lonardo F Int J Cancer; 2006 Jul; 119(2):441-54. PubMed ID: 16470840 [TBL] [Abstract][Full Text] [Related]
5. Development and therapeutic options for the treatment of raloxifene-stimulated breast cancer in athymic mice. O'Regan RM; Osipo C; Ariazi E; Lee ES; Meeke K; Morris C; Bertucci A; Sarker MA; Grigg R; Jordan VC Clin Cancer Res; 2006 Apr; 12(7 Pt 1):2255-63. PubMed ID: 16609042 [TBL] [Abstract][Full Text] [Related]
6. Epidermal growth factor receptor (HER1) tyrosine kinase inhibitor ZD1839 (Iressa) inhibits HER2/neu (erbB2)-overexpressing breast cancer cells in vitro and in vivo. Moulder SL; Yakes FM; Muthuswamy SK; Bianco R; Simpson JF; Arteaga CL Cancer Res; 2001 Dec; 61(24):8887-95. PubMed ID: 11751413 [TBL] [Abstract][Full Text] [Related]
7. Antitumor activity of the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor gefitinib (ZD1839, Iressa) in non-small cell lung cancer cell lines correlates with gene copy number and EGFR mutations but not EGFR protein levels. Helfrich BA; Raben D; Varella-Garcia M; Gustafson D; Chan DC; Bemis L; Coldren C; Barón A; Zeng C; Franklin WA; Hirsch FR; Gazdar A; Minna J; Bunn PA Clin Cancer Res; 2006 Dec; 12(23):7117-25. PubMed ID: 17145836 [TBL] [Abstract][Full Text] [Related]
9. 3,3'-diindolylmethane and paclitaxel act synergistically to promote apoptosis in HER2/Neu human breast cancer cells. McGuire KP; Ngoubilly N; Neavyn M; Lanza-Jacoby S J Surg Res; 2006 May; 132(2):208-13. PubMed ID: 16580691 [TBL] [Abstract][Full Text] [Related]
10. Inhibition of the AKT/mTOR and erbB pathways by gefitinib, perifosine and analogs of gonadotropin-releasing hormone I and II to overcome tamoxifen resistance in breast cancer cells. Block M; Gründker C; Fister S; Kubin J; Wilkens L; Mueller MD; Hemmerlein B; Emons G; Günthert AR Int J Oncol; 2012 Nov; 41(5):1845-54. PubMed ID: 22922893 [TBL] [Abstract][Full Text] [Related]
11. Resistance to small molecule inhibitors of epidermal growth factor receptor in malignant gliomas. Li B; Chang CM; Yuan M; McKenna WG; Shu HK Cancer Res; 2003 Nov; 63(21):7443-50. PubMed ID: 14612544 [TBL] [Abstract][Full Text] [Related]
12. Breast cancer cells with acquired resistance to the EGFR tyrosine kinase inhibitor gefitinib show persistent activation of MAPK signaling. Normanno N; Campiglio M; Maiello MR; De Luca A; Mancino M; Gallo M; D'Alessio A; Menard S Breast Cancer Res Treat; 2008 Nov; 112(1):25-33. PubMed ID: 18060492 [TBL] [Abstract][Full Text] [Related]
13. Combined epidermal growth factor receptor targeting with the tyrosine kinase inhibitor gefitinib (ZD1839) and the monoclonal antibody cetuximab (IMC-C225): superiority over single-agent receptor targeting. Matar P; Rojo F; Cassia R; Moreno-Bueno G; Di Cosimo S; Tabernero J; Guzmán M; Rodriguez S; Arribas J; Palacios J; Baselga J Clin Cancer Res; 2004 Oct; 10(19):6487-501. PubMed ID: 15475436 [TBL] [Abstract][Full Text] [Related]
14. Chemoresistant tumor cell lines display altered epidermal growth factor receptor and HER3 signaling and enhanced sensitivity to gefitinib. Servidei T; Riccardi A; Mozzetti S; Ferlini C; Riccardi R Int J Cancer; 2008 Dec; 123(12):2939-49. PubMed ID: 18803287 [TBL] [Abstract][Full Text] [Related]
15. Novel targeted approaches to treating biliary tract cancer: the dual epidermal growth factor receptor and ErbB-2 tyrosine kinase inhibitor NVP-AEE788 is more efficient than the epidermal growth factor receptor inhibitors gefitinib and erlotinib. Wiedmann M; Feisthammel J; Blüthner T; Tannapfel A; Kamenz T; Kluge A; Mössner J; Caca K Anticancer Drugs; 2006 Aug; 17(7):783-95. PubMed ID: 16926628 [TBL] [Abstract][Full Text] [Related]
16. Gefitinib prevents cancer progression in mice expressing the activated rat HER2/neu. Piechocki MP; Dibbley SK; Lonardo F; Yoo GH Int J Cancer; 2008 Apr; 122(8):1722-9. PubMed ID: 18076070 [TBL] [Abstract][Full Text] [Related]
17. Mechanisms of tumor regression and resistance to estrogen deprivation and fulvestrant in a model of estrogen receptor-positive, HER-2/neu-positive breast cancer. Massarweh S; Osborne CK; Jiang S; Wakeling AE; Rimawi M; Mohsin SK; Hilsenbeck S; Schiff R Cancer Res; 2006 Aug; 66(16):8266-73. PubMed ID: 16912207 [TBL] [Abstract][Full Text] [Related]
18. Novel Hsp90 inhibitor FW-04-806 displays potent antitumor effects in HER2-positive breast cancer cells as a single agent or in combination with lapatinib. Huang W; Wu QD; Zhang M; Kong YL; Cao PR; Zheng W; Xu JH; Ye M Cancer Lett; 2015 Jan; 356(2 Pt B):862-71. PubMed ID: 25449780 [TBL] [Abstract][Full Text] [Related]
19. The interplay of HER2/HER3/PI3K and EGFR/HER2/PLC-γ1 signalling in breast cancer cell migration and dissemination. Balz LM; Bartkowiak K; Andreas A; Pantel K; Niggemann B; Zänker KS; Brandt BH; Dittmar T J Pathol; 2012 Jun; 227(2):234-44. PubMed ID: 22262199 [TBL] [Abstract][Full Text] [Related]
20. Transcriptional profiling identifies cyclin D1 as a critical downstream effector of mutant epidermal growth factor receptor signaling. Kobayashi S; Shimamura T; Monti S; Steidl U; Hetherington CJ; Lowell AM; Golub T; Meyerson M; Tenen DG; Shapiro GI; Halmos B Cancer Res; 2006 Dec; 66(23):11389-98. PubMed ID: 17145885 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]