BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

245 related articles for article (PubMed ID: 17644448)

  • 1. Growth stimulation of UV-induced DNA damage retaining epidermal basal cells gives rise to clusters of p53 overexpressing cells.
    Nijhof JG; Mulder AM; Speksnijder EN; Hoogervorst EM; Mullenders LH; de Gruijl FR
    DNA Repair (Amst); 2007 Nov; 6(11):1642-50. PubMed ID: 17644448
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Epidermal stem and progenitor cells in murine epidermis accumulate UV damage despite NER proficiency.
    Nijhof JG; van Pelt C; Mulder AA; Mitchell DL; Mullenders LH; de Gruijl FR
    Carcinogenesis; 2007 Apr; 28(4):792-800. PubMed ID: 17127714
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Time course for early adaptive responses to ultraviolet B light in the epidermis of SKH-1 mice.
    Lu YP; Lou YR; Yen P; Mitchell D; Huang MT; Conney AH
    Cancer Res; 1999 Sep; 59(18):4591-602. PubMed ID: 10493513
    [TBL] [Abstract][Full Text] [Related]  

  • 4. UV-induced ablation of the epidermal basal layer including p53-mutant clones resets UV carcinogenesis showing squamous cell carcinomas to originate from interfollicular epidermis.
    Rebel HG; Bodmann CA; van de Glind GC; de Gruijl FR
    Carcinogenesis; 2012 Mar; 33(3):714-20. PubMed ID: 22227037
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Early events in UV carcinogenesis--DNA damage, target cells and mutant p53 foci.
    de Gruijl FR; Rebel H
    Photochem Photobiol; 2008; 84(2):382-7. PubMed ID: 18221455
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Fractionation of a tumor-initiating UV dose introduces DNA damage-retaining cells in hairless mouse skin and renders subsequent TPA-promoted tumors non-regressing.
    van de Glind G; Rebel H; van Kempen M; Tensen K; de Gruijl F
    Oncotarget; 2016 Feb; 7(7):8067-77. PubMed ID: 26797757
    [TBL] [Abstract][Full Text] [Related]  

  • 7. UV-induced DNA damage and mutations in Hupki (human p53 knock-in) mice recapitulate p53 hotspot alterations in sun-exposed human skin.
    Luo JL; Tong WM; Yoon JH; Hergenhahn M; Koomagi R; Yang Q; Galendo D; Pfeifer GP; Wang ZQ; Hollstein M
    Cancer Res; 2001 Nov; 61(22):8158-63. PubMed ID: 11719445
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Early p53-positive foci as indicators of tumor risk in ultraviolet-exposed hairless mice: kinetics of induction, effects of DNA repair deficiency, and p53 heterozygosity.
    Rebel H; Mosnier LO; Berg RJ; Westerman-de Vries A; van Steeg H; van Kranen HJ; de Gruijl FR
    Cancer Res; 2001 Feb; 61(3):977-83. PubMed ID: 11221893
    [TBL] [Abstract][Full Text] [Related]  

  • 9. More epidermal p53 patches adjacent to skin carcinomas in renal transplant recipients than in immunocompetent patients: the role of azathioprine.
    de Graaf YG; Rebel H; Elghalbzouri A; Cramers P; Nellen RG; Willemze R; Bouwes Bavinck JN; de Gruijl FR
    Exp Dermatol; 2008 Apr; 17(4):349-55. PubMed ID: 17979968
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Silibinin prevents ultraviolet radiation-caused skin damages in SKH-1 hairless mice via a decrease in thymine dimer positive cells and an up-regulation of p53-p21/Cip1 in epidermis.
    Dhanalakshmi S; Mallikarjuna GU; Singh RP; Agarwal R
    Carcinogenesis; 2004 Aug; 25(8):1459-65. PubMed ID: 15033902
    [TBL] [Abstract][Full Text] [Related]  

  • 11. In situ molecular dosimetry and tumor risk: UV-induced DNA damage and tumor latency time.
    de Gruijl FR; Berg RJ
    Photochem Photobiol; 1998 Oct; 68(4):555-60. PubMed ID: 9796438
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Administration of green tea or caffeine enhances the disappearance of UVB-induced patches of mutant p53 positive epidermal cells in SKH-1 mice.
    Lu YP; Lou YR; Liao J; Xie JG; Peng QY; Yang CS; Conney AH
    Carcinogenesis; 2005 Aug; 26(8):1465-72. PubMed ID: 15817611
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Patches of mutant p53-immunoreactive epidermal cells induced by chronic UVB Irradiation harbor the same p53 mutations as squamous cell carcinomas in the skin of hairless SKH-1 mice.
    Kramata P; Lu YP; Lou YR; Singh RN; Kwon SM; Conney AH
    Cancer Res; 2005 May; 65(9):3577-85. PubMed ID: 15867351
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of apoptosis by p53 in UV-irradiated human epidermis, psoriatic plaques and senescent keratinocytes.
    Qin JZ; Chaturvedi V; Denning MF; Bacon P; Panella J; Choubey D; Nickoloff BJ
    Oncogene; 2002 May; 21(19):2991-3002. PubMed ID: 12082529
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effect of administration of caffeine or green tea on the mutation profile in the p53 gene in early mutant p53-positive patches of epidermal cells induced by chronic UVB-irradiation of hairless SKH-1 mice.
    Kramata P; Lu YP; Lou YR; Cohen JL; Olcha M; Liu S; Conney AH
    Carcinogenesis; 2005 Nov; 26(11):1965-74. PubMed ID: 15975959
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Relationship between UV-induced mutant p53 patches and skin tumours, analysed by mutation spectra and by induction kinetics in various DNA-repair-deficient mice.
    Rebel H; Kram N; Westerman A; Banus S; van Kranen HJ; de Gruijl FR
    Carcinogenesis; 2005 Dec; 26(12):2123-30. PubMed ID: 16051635
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mutation spectrum in UVB-exposed skin epidermis of Xpa-knockout mice: frequent recovery of triplet mutations.
    Ikehata H; Yanase F; Mori T; Nikaido O; Tanaka K; Ono T
    Environ Mol Mutagen; 2007 Jan; 48(1):1-13. PubMed ID: 17163503
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Protective effect of the Baicalin against DNA damage induced by ultraviolet B irradiation to mouse epidermis.
    Bing-Rong Z; Song-Liang J; Xiao-E C; Xiang-Fei L; Bao-Xiang C; Jie G; Dan L
    Photodermatol Photoimmunol Photomed; 2008 Aug; 24(4):175-82. PubMed ID: 18717958
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dietary feeding of silibinin prevents early biomarkers of UVB radiation-induced carcinogenesis in SKH-1 hairless mouse epidermis.
    Gu M; Dhanalakshmi S; Singh RP; Agarwal R
    Cancer Epidemiol Biomarkers Prev; 2005 May; 14(5):1344-9. PubMed ID: 15894701
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of cyclobutane pyrimidine dimer formation in epidermal p53 gene of UV-irradiated mice by alpha-tocopherol.
    Chen W; Barthelman M; Martinez J; Alberts D; Gensler HL
    Nutr Cancer; 1997; 29(3):205-11. PubMed ID: 9457740
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.