BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

372 related articles for article (PubMed ID: 17652171)

  • 1. Dynamic PolyConjugates for targeted in vivo delivery of siRNA to hepatocytes.
    Rozema DB; Lewis DL; Wakefield DH; Wong SC; Klein JJ; Roesch PL; Bertin SL; Reppen TW; Chu Q; Blokhin AV; Hagstrom JE; Wolff JA
    Proc Natl Acad Sci U S A; 2007 Aug; 104(32):12982-7. PubMed ID: 17652171
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Efficient systemic delivery of siRNA to the mouse liver by pegylated lipopolymer.
    Liu J; Van S; Ma N; Yu L
    Int J Pharm; 2012 May; 427(1):58-63. PubMed ID: 22100515
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Endosomolytic bioreducible poly(amido amine disulfide) polymer conjugates for the in vivo systemic delivery of siRNA therapeutics.
    Parmar RG; Busuek M; Walsh ES; Leander KR; Howell BJ; Sepp-Lorenzino L; Kemp E; Crocker LS; Leone A; Kochansky CJ; Carr BA; Garbaccio RM; Colletti SL; Wang W
    Bioconjug Chem; 2013 Apr; 24(4):640-7. PubMed ID: 23496378
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Co-injection of a targeted, reversibly masked endosomolytic polymer dramatically improves the efficacy of cholesterol-conjugated small interfering RNAs in vivo.
    Wong SC; Klein JJ; Hamilton HL; Chu Q; Frey CL; Trubetskoy VS; Hegge J; Wakefield D; Rozema DB; Lewis DL
    Nucleic Acid Ther; 2012 Dec; 22(6):380-90. PubMed ID: 23181701
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeted in vivo delivery of siRNA and an endosome-releasing agent to hepatocytes.
    Sebestyén MG; Wong SC; Trubetskoy V; Lewis DL; Wooddell CI
    Methods Mol Biol; 2015; 1218():163-86. PubMed ID: 25319651
    [TBL] [Abstract][Full Text] [Related]  

  • 6. N-acetylgalactosamine functionalized mixed micellar nanoparticles for targeted delivery of siRNA to liver.
    Wang HX; Xiong MH; Wang YC; Zhu J; Wang J
    J Control Release; 2013 Mar; 166(2):106-14. PubMed ID: 23266452
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Efficient in vivo delivery of siRNA to the liver by conjugation of alpha-tocopherol.
    Nishina K; Unno T; Uno Y; Kubodera T; Kanouchi T; Mizusawa H; Yokota T
    Mol Ther; 2008 Apr; 16(4):734-40. PubMed ID: 18362929
    [TBL] [Abstract][Full Text] [Related]  

  • 8. An in vivo evaluation of amphiphilic, biodegradable peptide copolymers as siRNA delivery agents.
    Barrett SE; Abrams MT; Burke R; Carr BA; Crocker LS; Garbaccio RM; Howell BJ; Kemp EA; Kowtoniuk RA; Latham AH; Leander KR; Leone AM; Patel M; Pechenov S; Pudvah NT; Riley S; Sepp-Lorenzino L; Walsh ES; Williams JM; Colletti SL
    Int J Pharm; 2014 May; 466(1-2):58-67. PubMed ID: 24607208
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel endosomolytic poly(amido amine) polymer conjugates for systemic delivery of siRNA to hepatocytes in rodents and nonhuman primates.
    Parmar RG; Poslusney M; Busuek M; Williams JM; Garbaccio R; Leander K; Walsh E; Howell B; Sepp-Lorenzino L; Riley S; Patel M; Kemp E; Latham A; Leone A; Soli E; Burke RS; Carr B; Colletti SL; Wang W
    Bioconjug Chem; 2014 May; 25(5):896-906. PubMed ID: 24742200
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Transcriptional and phenotypic comparisons of Ppara knockout and siRNA knockdown mice.
    De Souza AT; Dai X; Spencer AG; Reppen T; Menzie A; Roesch PL; He Y; Caguyong MJ; Bloomer S; Herweijer H; Wolff JA; Hagstrom JE; Lewis DL; Linsley PS; Ulrich RG
    Nucleic Acids Res; 2006; 34(16):4486-94. PubMed ID: 16945951
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enteral siRNA delivery technique for therapeutic gene silencing in the liver via the lymphatic route.
    Murakami M; Nishina K; Watanabe C; Yoshida-Tanaka K; Piao W; Kuwahara H; Horikiri Y; Miyata K; Nishiyama N; Kataoka K; Yoshida M; Mizusawa H; Yokota T
    Sci Rep; 2015 Nov; 5():17035. PubMed ID: 26593819
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Efficient reduction of serum cholesterol by combining a liver-targeted gene delivery system with chemically modified apolipoprotein B siRNA.
    Kang JH; Tachibana Y; Obika S; Harada-Shiba M; Yamaoka T
    J Control Release; 2012 Oct; 163(2):119-24. PubMed ID: 22974833
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Triplex Hybridization of siRNA with Bifacial Glycopolymer Nucleic Acid Enables Hepatocyte-Targeted Silencing.
    Xia X; Zhou Z; DeSantis C; Rossi JJ; Bong D
    ACS Chem Biol; 2019 Jun; 14(6):1310-1318. PubMed ID: 31141333
    [TBL] [Abstract][Full Text] [Related]  

  • 14. In vivo siRNA delivery with dendritic poly(L-lysine) for the treatment of hypercholesterolemia.
    Watanabe K; Harada-Shiba M; Suzuki A; Gokuden R; Kurihara R; Sugao Y; Mori T; Katayama Y; Niidome T
    Mol Biosyst; 2009 Nov; 5(11):1306-10. PubMed ID: 19823746
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RNAi-mediated gene silencing in non-human primates.
    Zimmermann TS; Lee AC; Akinc A; Bramlage B; Bumcrot D; Fedoruk MN; Harborth J; Heyes JA; Jeffs LB; John M; Judge AD; Lam K; McClintock K; Nechev LV; Palmer LR; Racie T; Röhl I; Seiffert S; Shanmugam S; Sood V; Soutschek J; Toudjarska I; Wheat AJ; Yaworski E; Zedalis W; Koteliansky V; Manoharan M; Vornlocher HP; MacLachlan I
    Nature; 2006 May; 441(7089):111-4. PubMed ID: 16565705
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Knockdown of apolipoprotein B, an atherogenic apolipoprotein, in HepG2 cells by lentivirus-mediated siRNA.
    Liao W; Ning G
    Biochem Biophys Res Commun; 2006 Jun; 344(2):478-83. PubMed ID: 16620782
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Quick nuclear transportation of siRNA and in vivo hepatic ApoB gene silencing with galactose-bearing polymeric carrier.
    Tachibana Y; Munisso MC; Kamata W; Kitagawa M; Harada-Shiba M; Yamaoka T
    J Biotechnol; 2014 Apr; 175():15-21. PubMed ID: 24530538
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Enhanced endosomal/lysosomal escape by distearoyl phosphoethanolamine-polycarboxybetaine lipid for systemic delivery of siRNA.
    Li Y; Cheng Q; Jiang Q; Huang Y; Liu H; Zhao Y; Cao W; Ma G; Dai F; Liang X; Liang Z; Zhang X
    J Control Release; 2014 Feb; 176():104-14. PubMed ID: 24365128
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sequential intravenous injection of anionic polymer and cationic lipoplex of siRNA could effectively deliver siRNA to the liver.
    Hattori Y; Arai S; Okamoto R; Hamada M; Kawano K; Yonemochi E
    Int J Pharm; 2014 Dec; 476(1-2):289-98. PubMed ID: 25290812
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs.
    Soutschek J; Akinc A; Bramlage B; Charisse K; Constien R; Donoghue M; Elbashir S; Geick A; Hadwiger P; Harborth J; John M; Kesavan V; Lavine G; Pandey RK; Racie T; Rajeev KG; Röhl I; Toudjarska I; Wang G; Wuschko S; Bumcrot D; Koteliansky V; Limmer S; Manoharan M; Vornlocher HP
    Nature; 2004 Nov; 432(7014):173-8. PubMed ID: 15538359
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.