BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

186 related articles for article (PubMed ID: 17652214)

  • 1. Elevated free fatty acids attenuate the insulin-induced suppression of PDK4 gene expression in human skeletal muscle: potential role of intramuscular long-chain acyl-coenzyme A.
    Tsintzas K; Chokkalingam K; Jewell K; Norton L; Macdonald IA; Constantin-Teodosiu D
    J Clin Endocrinol Metab; 2007 Oct; 92(10):3967-72. PubMed ID: 17652214
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Fatty acid-induced insulin resistance: decreased muscle PI3K activation but unchanged Akt phosphorylation.
    Kruszynska YT; Worrall DS; Ofrecio J; Frias JP; Macaraeg G; Olefsky JM
    J Clin Endocrinol Metab; 2002 Jan; 87(1):226-34. PubMed ID: 11788651
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Insulin regulation of skeletal muscle PDK4 mRNA expression is impaired in acute insulin-resistant states.
    Kim YI; Lee FN; Choi WS; Lee S; Youn JH
    Diabetes; 2006 Aug; 55(8):2311-7. PubMed ID: 16873695
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Prior thiazolidinedione treatment preserves insulin sensitivity in normal rats during acute fatty acid elevation: role of the liver.
    Ye JM; Frangioudakis G; Iglesias MA; Furler SM; Ellis B; Dzamko N; Cooney GJ; Kraegen EW
    Endocrinology; 2002 Dec; 143(12):4527-35. PubMed ID: 12446579
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dissociation between fat-induced in vivo insulin resistance and proximal insulin signaling in skeletal muscle in men at risk for type 2 diabetes.
    Storgaard H; Jensen CB; Björnholm M; Song XM; Madsbad S; Zierath JR; Vaag AA
    J Clin Endocrinol Metab; 2004 Mar; 89(3):1301-11. PubMed ID: 15001626
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mechanisms of liver and muscle insulin resistance induced by chronic high-fat feeding.
    Oakes ND; Cooney GJ; Camilleri S; Chisholm DJ; Kraegen EW
    Diabetes; 1997 Nov; 46(11):1768-74. PubMed ID: 9356024
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Long- and medium-chain fatty acids induce insulin resistance to a similar extent in humans despite marked differences in muscle fat accumulation.
    Hoeks J; Mensink M; Hesselink MK; Ekroos K; Schrauwen P
    J Clin Endocrinol Metab; 2012 Jan; 97(1):208-16. PubMed ID: 22031508
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Basal and insulin-stimulated pyruvate dehydrogenase complex activation, glycogen synthesis and metabolic gene expression in human skeletal muscle the day after a single bout of exercise.
    Stephens FB; Norton L; Jewell K; Chokkalingam K; Parr T; Tsintzas K
    Exp Physiol; 2010 Jul; 95(7):808-18. PubMed ID: 20382667
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Increased malonyl-CoA levels in muscle from obese and type 2 diabetic subjects lead to decreased fatty acid oxidation and increased lipogenesis; thiazolidinedione treatment reverses these defects.
    Bandyopadhyay GK; Yu JG; Ofrecio J; Olefsky JM
    Diabetes; 2006 Aug; 55(8):2277-85. PubMed ID: 16873691
    [TBL] [Abstract][Full Text] [Related]  

  • 10. High-fat/low-carbohydrate diet reduces insulin-stimulated carbohydrate oxidation but stimulates nonoxidative glucose disposal in humans: An important role for skeletal muscle pyruvate dehydrogenase kinase 4.
    Chokkalingam K; Jewell K; Norton L; Littlewood J; van Loon LJ; Mansell P; Macdonald IA; Tsintzas K
    J Clin Endocrinol Metab; 2007 Jan; 92(1):284-92. PubMed ID: 17062764
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pharmacological activation of the pyruvate dehydrogenase complex reduces statin-mediated upregulation of FOXO gene targets and protects against statin myopathy in rodents.
    Mallinson JE; Constantin-Teodosiu D; Glaves PD; Martin EA; Davies WJ; Westwood FR; Sidaway JE; Greenhaff PL
    J Physiol; 2012 Dec; 590(24):6389-402. PubMed ID: 23045346
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effect of elevated lipid concentrations on human skeletal muscle gene expression.
    Tunstall RJ; Cameron-Smith D
    Metabolism; 2005 Jul; 54(7):952-9. PubMed ID: 15988707
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A potential role for Akt/FOXO signalling in both protein loss and the impairment of muscle carbohydrate oxidation during sepsis in rodent skeletal muscle.
    Crossland H; Constantin-Teodosiu D; Gardiner SM; Constantin D; Greenhaff PL
    J Physiol; 2008 Nov; 586(22):5589-600. PubMed ID: 18818241
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Insulin downregulates pyruvate dehydrogenase kinase (PDK) mRNA: potential mechanism contributing to increased lipid oxidation in insulin-resistant subjects.
    Majer M; Popov KM; Harris RA; Bogardus C; Prochazka M
    Mol Genet Metab; 1998 Oct; 65(2):181-6. PubMed ID: 9787110
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evidence against a role for insulin-signaling proteins PI 3-kinase and Akt in insulin resistance in human skeletal muscle induced by short-term GH infusion.
    Jessen N; Djurhuus CB; Jørgensen JO; Jensen LS; Møller N; Lund S; Schmitz O
    Am J Physiol Endocrinol Metab; 2005 Jan; 288(1):E194-9. PubMed ID: 15339744
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Insulin suppresses PDK-4 expression in skeletal muscle independently of plasma FFA.
    Lee FN; Zhang L; Zheng D; Choi WS; Youn JH
    Am J Physiol Endocrinol Metab; 2004 Jul; 287(1):E69-74. PubMed ID: 15026305
    [TBL] [Abstract][Full Text] [Related]  

  • 17. An acute increase in skeletal muscle carnitine content alters fuel metabolism in resting human skeletal muscle.
    Stephens FB; Constantin-Teodosiu D; Laithwaite D; Simpson EJ; Greenhaff PL
    J Clin Endocrinol Metab; 2006 Dec; 91(12):5013-8. PubMed ID: 16984983
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Changes in FAT/CD36, UCP2, UCP3 and GLUT4 gene expression during lipid infusion in rat skeletal and heart muscle.
    Vettor R; Fabris R; Serra R; Lombardi AM; Tonello C; Granzotto M; Marzolo MO; Carruba MO; Ricquier D; Federspil G; Nisoli E
    Int J Obes Relat Metab Disord; 2002 Jun; 26(6):838-47. PubMed ID: 12037655
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Saturated, but not n-6 polyunsaturated, fatty acids induce insulin resistance: role of intramuscular accumulation of lipid metabolites.
    Lee JS; Pinnamaneni SK; Eo SJ; Cho IH; Pyo JH; Kim CK; Sinclair AJ; Febbraio MA; Watt MJ
    J Appl Physiol (1985); 2006 May; 100(5):1467-74. PubMed ID: 16357064
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Salicylate prevents hepatic insulin resistance caused by short-term elevation of free fatty acids in vivo.
    Park E; Wong V; Guan X; Oprescu AI; Giacca A
    J Endocrinol; 2007 Nov; 195(2):323-31. PubMed ID: 17951543
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.