267 related articles for article (PubMed ID: 17655875)
1. Anti-obesity effects of small molecule melanin-concentrating hormone receptor 1 (MCHR1) antagonists.
Luthin DR
Life Sci; 2007 Jul; 81(6):423-40. PubMed ID: 17655875
[TBL] [Abstract][Full Text] [Related]
2. Biological examination of melanin concentrating hormone receptor 1: multi-tasking from the hypothalamus.
Rokosz LL; Hobbs DW
Drug News Perspect; 2006 Jun; 19(5):273-86. PubMed ID: 16941049
[TBL] [Abstract][Full Text] [Related]
3. Discovery of novel, orally available benzimidazoles as melanin concentrating hormone receptor 1 (MCHR1) antagonists.
Sasmal PK; Sasmal S; Rao PT; Venkatesham B; Roshaiah M; Abbineni C; Khanna I; Jadhav VP; Suresh J; Talwar R; Muzeeb S; Receveur JM; Frimurer TM; Rist Ø; Elster L; Högberg T
Bioorg Med Chem Lett; 2010 Sep; 20(18):5443-8. PubMed ID: 20724156
[TBL] [Abstract][Full Text] [Related]
4. Melanin-concentrating hormone receptor-1 antagonists as antiobesity therapeutics: current status.
Kowalski TJ; Sasikumar T
BioDrugs; 2007; 21(5):311-21. PubMed ID: 17896837
[TBL] [Abstract][Full Text] [Related]
5. Building a MCHR1 homology model provides insight into the receptor-antagonist contacts that are important for the development of new anti-obesity agents.
Cirauqui N; Schrey AK; Galiano S; Ceras J; Pérez-Silanes S; Aldana I; Monge A; Kühne R
Bioorg Med Chem; 2010 Nov; 18(21):7365-79. PubMed ID: 20932767
[TBL] [Abstract][Full Text] [Related]
6. Novel MCH1 receptor antagonists: a patent review.
Johansson A; Löfberg C
Expert Opin Ther Pat; 2015 Feb; 25(2):193-207. PubMed ID: 25522065
[TBL] [Abstract][Full Text] [Related]
7. 6-(4-chlorophenyl)-3-substituted-thieno[3,2-d]pyrimidin-4(3H)-one-based melanin-concentrating hormone receptor 1 antagonist.
Tavares FX; Al-Barazanji KA; Bishop MJ; Britt CS; Carlton DL; Cooper JP; Feldman PL; Garrido DM; Goetz AS; Grizzle MK; Hertzog DL; Ignar DM; Lang DG; McIntyre MS; Ott RJ; Peat AJ; Zhou HQ
J Med Chem; 2006 Nov; 49(24):7108-18. PubMed ID: 17125263
[TBL] [Abstract][Full Text] [Related]
8. Identification of 2-(4-benzyloxyphenyl)-N- [1-(2-pyrrolidin-1-yl-ethyl)-1H-indazol-6-yl]acetamide, an orally efficacious melanin-concentrating hormone receptor 1 antagonist for the treatment of obesity.
Souers AJ; Gao J; Brune M; Bush E; Wodka D; Vasudevan A; Judd AS; Mulhern M; Brodjian S; Dayton B; Shapiro R; Hernandez LE; Marsh KC; Sham HL; Collins CA; Kym PR
J Med Chem; 2005 Mar; 48(5):1318-21. PubMed ID: 15743174
[TBL] [Abstract][Full Text] [Related]
9. Melanin concentrating hormone receptor 1 (MCHR1) antagonists-Still a viable approach for obesity treatment?
Högberg T; Frimurer TM; Sasmal PK
Bioorg Med Chem Lett; 2012 Oct; 22(19):6039-47. PubMed ID: 22954736
[TBL] [Abstract][Full Text] [Related]
10. Antiobesity effects of melanin-concentrating hormone receptor 1 (MCH-R1) antagonists.
Cheon HG
Handb Exp Pharmacol; 2012; (209):383-403. PubMed ID: 22249825
[TBL] [Abstract][Full Text] [Related]
11. Discovery of orally efficacious melanin-concentrating hormone receptor-1 antagonists as antiobesity agents. Synthesis, SAR, and biological evaluation of bicyclo[3.1.0]hexyl ureas.
McBriar MD; Guzik H; Shapiro S; Paruchova J; Xu R; Palani A; Clader JW; Cox K; Greenlee WJ; Hawes BE; Kowalski TJ; O'neill K; Spar BD; Weig B; Weston DJ; Farley C; Cook J
J Med Chem; 2006 Apr; 49(7):2294-310. PubMed ID: 16570926
[TBL] [Abstract][Full Text] [Related]
12. Biological examination of melanin concentrating hormone receptor 1: multi-tasking from the hypothalamus.
Rokosz LL; Hobbs DW
Timely Top Med Cardiovasc Dis; 2006 Sep; 10():E23. PubMed ID: 17066150
[TBL] [Abstract][Full Text] [Related]
13. Characterization of a neuronal cell line expressing native human melanin-concentrating hormone receptor 1 (MCHR1).
Fry D; Dayton B; Brodjian S; Ogiela C; Sidorowicz H; Frost LJ; McNally T; Reilly RM; Collins CA
Int J Biochem Cell Biol; 2006; 38(8):1290-9. PubMed ID: 16524757
[TBL] [Abstract][Full Text] [Related]
14. A study of the involvement of melanin-concentrating hormone receptor 1 (MCHR1) in murine models of depression.
Roy M; David N; Cueva M; Giorgetti M
Biol Psychiatry; 2007 Jan; 61(2):174-80. PubMed ID: 16934771
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 2.
Vasudevan A; Wodka D; Verzal MK; Souers AJ; Gao J; Brodjian S; Fry D; Dayton B; Marsh KC; Hernandez LE; Ogiela CA; Collins CA; Kym PR
Bioorg Med Chem Lett; 2004 Oct; 14(19):4879-82. PubMed ID: 15341943
[TBL] [Abstract][Full Text] [Related]
16. Discovery and characterization of aminopiperidinecoumarin melanin concentrating hormone receptor 1 antagonists.
Kym PR; Iyengar R; Souers AJ; Lynch JK; Judd AS; Gao J; Freeman J; Mulhern M; Zhao G; Vasudevan A; Wodka D; Blackburn C; Brown J; Che JL; Cullis C; Lai SJ; LaMarche MJ; Marsilje T; Roses J; Sells T; Geddes B; Govek E; Patane M; Fry D; Dayton BD; Brodjian S; Falls D; Brune M; Bush E; Shapiro R; Knourek-Segel V; Fey T; McDowell C; Reinhart GA; Preusser LC; Marsh K; Hernandez L; Sham HL; Collins CA
J Med Chem; 2005 Sep; 48(19):5888-91. PubMed ID: 16161992
[TBL] [Abstract][Full Text] [Related]
17. Prospects for obesity treatment: MCH receptor antagonists.
Collins CA; Kym PR
Curr Opin Investig Drugs; 2003 Apr; 4(4):386-94. PubMed ID: 12808876
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and evaluation of urea-based indazoles as melanin-concentrating hormone receptor 1 antagonists for the treatment of obesity.
Souers AJ; Gao J; Wodka D; Judd AS; Mulhern MM; Napier JJ; Brune ME; Bush EN; Brodjian SJ; Dayton BD; Shapiro R; Hernandez LE; Marsh KC; Sham HL; Collins CA; Kym PR
Bioorg Med Chem Lett; 2005 Jun; 15(11):2752-7. PubMed ID: 15911251
[TBL] [Abstract][Full Text] [Related]
19. Discovery of novel diarylketoxime derivatives as selective and orally active melanin-concentrating hormone 1 receptor antagonists.
Suzuki T; Kameda M; Ando M; Miyazoe H; Sekino E; Ito S; Masutani K; Kamijo K; Takezawa A; Moriya M; Ito M; Ito J; Nakase K; Matsushita H; Ishihara A; Takenaga N; Tokita S; Kanatani A; Sato N; Fukami T
Bioorg Med Chem Lett; 2009 Sep; 19(18):5339-45. PubMed ID: 19683441
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 1.
Souers AJ; Wodka D; Gao J; Lewis JC; Vasudevan A; Gentles R; Brodjian S; Dayton B; Ogiela CA; Fry D; Hernandez LE; Marsh KC; Collins CA; Kym PR
Bioorg Med Chem Lett; 2004 Oct; 14(19):4873-7. PubMed ID: 15341942
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
