BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

134 related articles for article (PubMed ID: 17666395)

  • 1. Disulfide bond mediates aggregation, toxicity, and ubiquitylation of familial amyotrophic lateral sclerosis-linked mutant SOD1.
    Niwa J; Yamada S; Ishigaki S; Sone J; Takahashi M; Katsuno M; Tanaka F; Doyu M; Sobue G
    J Biol Chem; 2007 Sep; 282(38):28087-95. PubMed ID: 17666395
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Disulfide cross-linked protein represents a significant fraction of ALS-associated Cu, Zn-superoxide dismutase aggregates in spinal cords of model mice.
    Furukawa Y; Fu R; Deng HX; Siddique T; O'Halloran TV
    Proc Natl Acad Sci U S A; 2006 May; 103(18):7148-53. PubMed ID: 16636274
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A limited role for disulfide cross-linking in the aggregation of mutant SOD1 linked to familial amyotrophic lateral sclerosis.
    Karch CM; Borchelt DR
    J Biol Chem; 2008 May; 283(20):13528-37. PubMed ID: 18316367
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Conversion to the amyotrophic lateral sclerosis phenotype is associated with intermolecular linked insoluble aggregates of SOD1 in mitochondria.
    Deng HX; Shi Y; Furukawa Y; Zhai H; Fu R; Liu E; Gorrie GH; Khan MS; Hung WY; Bigio EH; Lukas T; Dal Canto MC; O'Halloran TV; Siddique T
    Proc Natl Acad Sci U S A; 2006 May; 103(18):7142-7. PubMed ID: 16636275
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mapping superoxide dismutase 1 domains of non-native interaction: roles of intra- and intermolecular disulfide bonding in aggregation.
    Wang J; Xu G; Borchelt DR
    J Neurochem; 2006 Mar; 96(5):1277-88. PubMed ID: 16441516
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Complete loss of post-translational modifications triggers fibrillar aggregation of SOD1 in the familial form of amyotrophic lateral sclerosis.
    Furukawa Y; Kaneko K; Yamanaka K; O'Halloran TV; Nukina N
    J Biol Chem; 2008 Aug; 283(35):24167-76. PubMed ID: 18552350
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Elevated free nitrotyrosine levels, but not protein-bound nitrotyrosine or hydroxyl radicals, throughout amyotrophic lateral sclerosis (ALS)-like disease implicate tyrosine nitration as an aberrant in vivo property of one familial ALS-linked superoxide dismutase 1 mutant.
    Bruijn LI; Beal MF; Becher MW; Schulz JB; Wong PC; Price DL; Cleveland DW
    Proc Natl Acad Sci U S A; 1997 Jul; 94(14):7606-11. PubMed ID: 9207139
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hydrogen-deuterium exchange in vivo to measure turnover of an ALS-associated mutant SOD1 protein in spinal cord of mice.
    Farr GW; Ying Z; Fenton WA; Horwich AL
    Protein Sci; 2011 Oct; 20(10):1692-6. PubMed ID: 21780215
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Conformational Disorder of the Most Immature Cu, Zn-Superoxide Dismutase Leading to Amyotrophic Lateral Sclerosis.
    Furukawa Y; Anzai I; Akiyama S; Imai M; Cruz FJ; Saio T; Nagasawa K; Nomura T; Ishimori K
    J Biol Chem; 2016 Feb; 291(8):4144-55. PubMed ID: 26694608
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A novel variant of human superoxide dismutase 1 harboring amyotrophic lateral sclerosis-associated and experimental mutations in metal-binding residues and free cysteines lacks toxicity in vivo.
    Prudencio M; Lelie H; Brown HH; Whitelegge JP; Valentine JS; Borchelt DR
    J Neurochem; 2012 May; 121(3):475-85. PubMed ID: 22332887
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Posttranslational modifications in Cu,Zn-superoxide dismutase and mutations associated with amyotrophic lateral sclerosis.
    Furukawa Y; O'Halloran TV
    Antioxid Redox Signal; 2006; 8(5-6):847-67. PubMed ID: 16771675
    [TBL] [Abstract][Full Text] [Related]  

  • 12. An examination of alpha B-crystallin as a modifier of SOD1 aggregate pathology and toxicity in models of familial amyotrophic lateral sclerosis.
    Karch CM; Borchelt DR
    J Neurochem; 2010 Jun; 113(5):1092-100. PubMed ID: 20067574
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Evaluating protein cross-linking as a therapeutic strategy to stabilize SOD1 variants in a mouse model of familial ALS.
    Hossain MA; Sarin R; Donnelly DP; Miller BC; Weiss A; McAlary L; Antonyuk SV; Salisbury JP; Amin J; Conway JB; Watson SS; Winters JN; Xu Y; Alam N; Brahme RR; Shahbazian H; Sivasankar D; Padmakumar S; Sattarova A; Ponmudiyan AC; Gawde T; Verrill DE; Yang W; Kannapadi S; Plant LD; Auclair JR; Makowski L; Petsko GA; Ringe D; Agar NYR; Greenblatt DJ; Ondrechen MJ; Chen Y; Yerbury JJ; Manetsch R; Hasnain SS; Brown RH; Agar JN
    PLoS Biol; 2024 Jan; 22(1):e3002462. PubMed ID: 38289969
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Unveiling local and global conformational changes and allosteric communications in SOD1 systems using molecular dynamics simulation and network analyses.
    Basith S; Manavalan B; Lee G
    Comput Biol Med; 2024 Jan; 168():107688. PubMed ID: 37988788
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Functional consequences of familial ALS-associated SOD1
    Verma S; Vats A; Ahuja V; Vats K; Khurana S; Vats Y; Gourie-Devi M; Wajid S; Ganguly NK; Chakraborti P; Taneja V
    FASEB J; 2024 Feb; 38(3):e23461. PubMed ID: 38317639
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Aggregation modulating elements in mutant human superoxide dismutase 1.
    Karch CM; Borchelt DR
    Arch Biochem Biophys; 2010 Nov; 503(2):175-82. PubMed ID: 20682279
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Transient structural distortion of metal-free Cu/Zn superoxide dismutase triggers aberrant oligomerization.
    Teilum K; Smith MH; Schulz E; Christensen LC; Solomentsev G; Oliveberg M; Akke M
    Proc Natl Acad Sci U S A; 2009 Oct; 106(43):18273-8. PubMed ID: 19828437
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An ALS-associated KIF5A mutant forms oligomers and aggregates and induces neuronal toxicity.
    Nakano J; Chiba K; Niwa S
    Genes Cells; 2022 Jun; 27(6):421-435. PubMed ID: 35430760
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Generation of an induced pluripotent stem cell line, CSSi011-A (6534), from an Amyotrophic lateral sclerosis patient with heterozygous L145F mutation in SOD1 gene.
    D'Anzi A; Altieri F; Perciballi E; Ferrari D; Bernardini L; Goldoni M; Mazzini L; De Marchi F; Di Pierro A; D'Alfonso S; Gelati M; Vescovi AL; Rosati J
    Stem Cell Res; 2020 Jul; 47():101924. PubMed ID: 32739880
    [TBL] [Abstract][Full Text] [Related]  

  • 20. An Amyotrophic Lateral Sclerosis-Associated Mutant of C21ORF2 Is Stabilized by NEK1-Mediated Hyperphosphorylation and the Inability to Bind FBXO3.
    Watanabe Y; Nakagawa T; Akiyama T; Nakagawa M; Suzuki N; Warita H; Aoki M; Nakayama K
    iScience; 2020 Aug; 23(9):101491. PubMed ID: 32891887
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.