BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

244 related articles for article (PubMed ID: 17666400)

  • 1. Detection of reactive oxygen species via endogenous oxidative pentose phosphate cycle activity in response to oxygen concentration: implications for the mechanism of HIF-1alpha stabilization under moderate hypoxia.
    Tuttle SW; Maity A; Oprysko PR; Kachur AV; Ayene IS; Biaglow JE; Koch CJ
    J Biol Chem; 2007 Dec; 282(51):36790-6. PubMed ID: 17666400
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Stabilization of hypoxia-inducible factor-1alpha protein in hypoxia occurs independently of mitochondrial reactive oxygen species production.
    Chua YL; Dufour E; Dassa EP; Rustin P; Jacobs HT; Taylor CT; Hagen T
    J Biol Chem; 2010 Oct; 285(41):31277-84. PubMed ID: 20675386
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Multiple factors affecting cellular redox status and energy metabolism modulate hypoxia-inducible factor prolyl hydroxylase activity in vivo and in vitro.
    Pan Y; Mansfield KD; Bertozzi CC; Rudenko V; Chan DA; Giaccia AJ; Simon MC
    Mol Cell Biol; 2007 Feb; 27(3):912-25. PubMed ID: 17101781
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Qiliqiangxin attenuates hypoxia-induced injury in primary rat cardiac microvascular endothelial cells via promoting HIF-1α-dependent glycolysis.
    Wang Y; Han X; Fu M; Wang J; Song Y; Liu Y; Zhang J; Zhou J; Ge J
    J Cell Mol Med; 2018 May; 22(5):2791-2803. PubMed ID: 29502357
    [TBL] [Abstract][Full Text] [Related]  

  • 5. HIF-1α protects against oxidative stress by directly targeting mitochondria.
    Li HS; Zhou YN; Li L; Li SF; Long D; Chen XL; Zhang JB; Feng L; Li YP
    Redox Biol; 2019 Jul; 25():101109. PubMed ID: 30686776
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing.
    Chandel NS; McClintock DS; Feliciano CE; Wood TM; Melendez JA; Rodriguez AM; Schumacker PT
    J Biol Chem; 2000 Aug; 275(33):25130-8. PubMed ID: 10833514
    [TBL] [Abstract][Full Text] [Related]  

  • 7. NADPH oxidase-mitochondria axis-derived ROS mediate arsenite-induced HIF-1α stabilization by inhibiting prolyl hydroxylases activity.
    Li YN; Xi MM; Guo Y; Hai CX; Yang WL; Qin XJ
    Toxicol Lett; 2014 Jan; 224(2):165-74. PubMed ID: 24188932
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Src activates HIF-1α not through direct phosphorylation of HIF-1α specific prolyl-4 hydroxylase 2 but through activation of the NADPH oxidase/Rac pathway.
    Lee HY; Lee T; Lee N; Yang EG; Lee C; Lee J; Moon EY; Ha J; Park H
    Carcinogenesis; 2011 May; 32(5):703-12. PubMed ID: 21335603
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Nitric oxide produced endogenously is responsible for hypoxia-induced HIF-1α stabilization in colon carcinoma cells.
    Chowdhury R; Godoy LC; Thiantanawat A; Trudel LJ; Deen WM; Wogan GN
    Chem Res Toxicol; 2012 Oct; 25(10):2194-202. PubMed ID: 22971010
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hypoxic but not anoxic stabilization of HIF-1alpha requires mitochondrial reactive oxygen species.
    Schroedl C; McClintock DS; Budinger GR; Chandel NS
    Am J Physiol Lung Cell Mol Physiol; 2002 Nov; 283(5):L922-31. PubMed ID: 12376345
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nitric oxide modulates oxygen sensing by hypoxia-inducible factor 1-dependent induction of prolyl hydroxylase 2.
    Berchner-Pfannschmidt U; Yamac H; Trinidad B; Fandrey J
    J Biol Chem; 2007 Jan; 282(3):1788-96. PubMed ID: 17060326
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role of reactive oxygen species in the regulation of HIF-1 by prolyl hydroxylase 2 under mild hypoxia.
    Niecknig H; Tug S; Reyes BD; Kirsch M; Fandrey J; Berchner-Pfannschmidt U
    Free Radic Res; 2012 Jun; 46(6):705-17. PubMed ID: 22360728
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cyanide preconditioning protects brain endothelial and NT2 neuron-like cells against glucotoxicity: role of mitochondrial reactive oxygen species and HIF-1α.
    Correia SC; Santos RX; Cardoso SM; Santos MS; Oliveira CR; Moreira PI
    Neurobiol Dis; 2012 Jan; 45(1):206-18. PubMed ID: 21854848
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effects of prolyl hydroxylase inhibitors on adipogenesis and hypoxia inducible factor 1 alpha levels under normoxic conditions.
    Floyd ZE; Kilroy G; Wu X; Gimble JM
    J Cell Biochem; 2007 Aug; 101(6):1545-57. PubMed ID: 17370314
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Suppression of hypoxia-inducible factor 1alpha (HIF-1alpha) transcriptional activity by the HIF prolyl hydroxylase EGLN1.
    To KK; Huang LE
    J Biol Chem; 2005 Nov; 280(45):38102-7. PubMed ID: 16157596
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Oligomycin inhibits HIF-1alpha expression in hypoxic tumor cells.
    Gong Y; Agani FH
    Am J Physiol Cell Physiol; 2005 May; 288(5):C1023-9. PubMed ID: 15840558
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Induction of HIF-1alpha expression by intermittent hypoxia: involvement of NADPH oxidase, Ca2+ signaling, prolyl hydroxylases, and mTOR.
    Yuan G; Nanduri J; Khan S; Semenza GL; Prabhakar NR
    J Cell Physiol; 2008 Dec; 217(3):674-85. PubMed ID: 18651560
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hypoxia Promotes Mitochondrial Complex I Abundance via HIF-1α in Complex III and Complex IV Eficient Cells.
    Saldana-Caboverde A; Nissanka N; Garcia S; Lombès A; Diaz F
    Cells; 2020 Sep; 9(10):. PubMed ID: 33003371
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Thrombopoietin (TPO) regulates HIF-1alpha levels through generation of mitochondrial reactive oxygen species.
    Yoshida K; Kirito K; Yongzhen H; Ozawa K; Kaushansky K; Komatsu N
    Int J Hematol; 2008 Jul; 88(1):43-51. PubMed ID: 18473128
    [TBL] [Abstract][Full Text] [Related]  

  • 20. NO restores HIF-1alpha hydroxylation during hypoxia: role of reactive oxygen species.
    Callapina M; Zhou J; Schmid T; Köhl R; Brüne B
    Free Radic Biol Med; 2005 Oct; 39(7):925-36. PubMed ID: 16140212
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.