BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

220 related articles for article (PubMed ID: 17671208)

  • 1. Inhibition of cysteine cathepsin protease activity enhances chemotherapy regimens by decreasing tumor growth and invasiveness in a mouse model of multistage cancer.
    Bell-McGuinn KM; Garfall AL; Bogyo M; Hanahan D; Joyce JA
    Cancer Res; 2007 Aug; 67(15):7378-85. PubMed ID: 17671208
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A multitargeted, metronomic, and maximum-tolerated dose "chemo-switch" regimen is antiangiogenic, producing objective responses and survival benefit in a mouse model of cancer.
    Pietras K; Hanahan D
    J Clin Oncol; 2005 Feb; 23(5):939-52. PubMed ID: 15557593
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Distinct roles for cysteine cathepsin genes in multistage tumorigenesis.
    Gocheva V; Zeng W; Ke D; Klimstra D; Reinheckel T; Peters C; Hanahan D; Joyce JA
    Genes Dev; 2006 Mar; 20(5):543-56. PubMed ID: 16481467
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A cathepsin K inhibitor reduces breast cancer induced osteolysis and skeletal tumor burden.
    Le Gall C; Bellahcène A; Bonnelye E; Gasser JA; Castronovo V; Green J; Zimmermann J; Clézardin P
    Cancer Res; 2007 Oct; 67(20):9894-902. PubMed ID: 17942921
    [TBL] [Abstract][Full Text] [Related]  

  • 5. mTOR inhibition sensitizes gastric cancer to alkylating chemotherapy in vivo.
    Cejka D; Preusser M; Fuereder T; Sieghart W; Werzowa J; Strommer S; Wacheck V
    Anticancer Res; 2008; 28(6A):3801-8. PubMed ID: 19189667
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Beneficial effect of metronomic chemotherapy on tumor suppression and survival in a rat model of hepatocellular carcinoma with liver cirrhosis.
    Park ST; Jang JW; Kim GD; Park JA; Hur W; Woo HY; Kim JD; Kwon JH; Yoo CR; Bae SH; Choi JY; Yoon SK
    Cancer Chemother Pharmacol; 2010 May; 65(6):1029-37. PubMed ID: 19701751
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cathepsins and pancreatic cancer: the 2012 update.
    Sulpizio S; Franceschini N; Piattelli A; Di Sebastiano P; Innocenti P; Selvaggi F
    Pancreatology; 2012; 12(5):395-401. PubMed ID: 23127526
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis.
    Joyce JA; Baruch A; Chehade K; Meyer-Morse N; Giraudo E; Tsai FY; Greenbaum DC; Hager JH; Bogyo M; Hanahan D
    Cancer Cell; 2004 May; 5(5):443-53. PubMed ID: 15144952
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cysteine cathepsin proteases as pharmacological targets in cancer.
    Palermo C; Joyce JA
    Trends Pharmacol Sci; 2008 Jan; 29(1):22-8. PubMed ID: 18037508
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification and pre-clinical testing of a reversible cathepsin protease inhibitor reveals anti-tumor efficacy in a pancreatic cancer model.
    Elie BT; Gocheva V; Shree T; Dalrymple SA; Holsinger LJ; Joyce JA
    Biochimie; 2010 Nov; 92(11):1618-24. PubMed ID: 20447439
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enhancing effect of new biological response modifier sulfoethylated (1-->3)-beta-D-glucan on antitumor activity of cyclophosphamide in the treatment of experimental murine leukoses.
    Khalikova TA; Korolenko TA; Zhanaeva SY; Kaledin VI; Kogan G
    Exp Oncol; 2006 Dec; 28(4):308-13. PubMed ID: 17285116
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Trial of the cysteine cathepsin inhibitor JPM-OEt on early and advanced mammary cancer stages in the MMTV-PyMT-transgenic mouse model.
    Schurigt U; Sevenich L; Vannier C; Gajda M; Schwinde A; Werner F; Stahl A; von Elverfeldt D; Becker AK; Bogyo M; Peters C; Reinheckel T
    Biol Chem; 2008 Aug; 389(8):1067-74. PubMed ID: 18710344
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Primary tumour expression of the cysteine cathepsin inhibitor Stefin A inhibits distant metastasis in breast cancer.
    Parker BS; Ciocca DR; Bidwell BN; Gago FE; Fanelli MA; George J; Slavin JL; Möller A; Steel R; Pouliot N; Eckhardt B; Henderson MA; Anderson RL
    J Pathol; 2008 Feb; 214(3):337-46. PubMed ID: 17985332
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antibody-mediated inhibition of cathepsin S blocks colorectal tumor invasion and angiogenesis.
    Burden RE; Gormley JA; Jaquin TJ; Small DM; Quinn DJ; Hegarty SM; Ward C; Walker B; Johnston JA; Olwill SA; Scott CJ
    Clin Cancer Res; 2009 Oct; 15(19):6042-51. PubMed ID: 19789302
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of Cathepsin S by Fsn0503 enhances the efficacy of chemotherapy in colorectal carcinomas.
    Burden RE; Gormley JA; Kuehn D; Ward C; Kwok HF; Gazdoiu M; McClurg A; Jaquin TJ; Johnston JA; Scott CJ; Olwill SA
    Biochimie; 2012 Feb; 94(2):487-93. PubMed ID: 21896304
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Low-dose metronomic combined with intermittent bolus-dose cyclophosphamide is an effective long-term chemotherapy treatment strategy.
    Shaked Y; Emmenegger U; Francia G; Chen L; Lee CR; Man S; Paraghamian A; Ben-David Y; Kerbel RS
    Cancer Res; 2005 Aug; 65(16):7045-51. PubMed ID: 16103050
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Upregulation of the cysteine protease inhibitor, cystatin SN, contributes to cell proliferation and cathepsin inhibition in gastric cancer.
    Choi EH; Kim JT; Kim JH; Kim SY; Song EY; Kim JW; Kim SY; Yeom YI; Kim IH; Lee HG
    Clin Chim Acta; 2009 Aug; 406(1-2):45-51. PubMed ID: 19463800
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A metronomic schedule of cyclophosphamide combined with PEGylated liposomal doxorubicin has a highly antitumor effect in an experimental pulmonary metastatic mouse model.
    Shiraga E; Barichello JM; Ishida T; Kiwada H
    Int J Pharm; 2008 Apr; 353(1-2):65-73. PubMed ID: 18155369
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Reduction of experimental human fibrosarcoma lung metastasis in mice by adenovirus-mediated cystatin C overexpression in the host.
    Kopitz C; Anton M; Gansbacher B; Krüger A
    Cancer Res; 2005 Oct; 65(19):8608-12. PubMed ID: 16204025
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Combined deletion of cathepsin protease family members reveals compensatory mechanisms in cancer.
    Akkari L; Gocheva V; Quick ML; Kester JC; Spencer AK; Garfall AL; Bowman RL; Joyce JA
    Genes Dev; 2016 Jan; 30(2):220-32. PubMed ID: 26773004
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.