396 related articles for article (PubMed ID: 17673311)
1. Arsenic trioxide sensitizes promonocytic leukemia cells to TNFalpha-induced apoptosis via p38-MAPK-regulated activation of both receptor-mediated and mitochondrial pathways.
Amrán D; Sánchez Y; Fernández C; Ramos AM; de Blas E; Bréard J; Calle C; Aller P
Biochim Biophys Acta; 2007 Nov; 1773(11):1653-63. PubMed ID: 17673311
[TBL] [Abstract][Full Text] [Related]
2. Genistein selectively potentiates arsenic trioxide-induced apoptosis in human leukemia cells via reactive oxygen species generation and activation of reactive oxygen species-inducible protein kinases (p38-MAPK, AMPK).
Sánchez Y; Amrán D; Fernández C; de Blas E; Aller P
Int J Cancer; 2008 Sep; 123(5):1205-14. PubMed ID: 18546268
[TBL] [Abstract][Full Text] [Related]
3. Pharmacologic inhibitors of extracellular signal-regulated kinase (ERKs) and c-Jun NH(2)-terminal kinase (JNK) decrease glutathione content and sensitize human promonocytic leukemia cells to arsenic trioxide-induced apoptosis.
Ramos AM; Fernandez C; Amrán D; Esteban D; de Blas E; Palacios MA; Aller P
J Cell Physiol; 2006 Dec; 209(3):1006-15. PubMed ID: 16972261
[TBL] [Abstract][Full Text] [Related]
4. Quercetin decreases intracellular GSH content and potentiates the apoptotic action of the antileukemic drug arsenic trioxide in human leukemia cell lines.
Ramos AM; Aller P
Biochem Pharmacol; 2008 May; 75(10):1912-23. PubMed ID: 18359480
[TBL] [Abstract][Full Text] [Related]
5. Curcumin stimulates reactive oxygen species production and potentiates apoptosis induction by the antitumor drugs arsenic trioxide and lonidamine in human myeloid leukemia cell lines.
Sánchez Y; Simón GP; Calviño E; de Blas E; Aller P
J Pharmacol Exp Ther; 2010 Oct; 335(1):114-23. PubMed ID: 20605902
[TBL] [Abstract][Full Text] [Related]
6. The role of p38 MAPK and JNK in Arsenic trioxide-induced mitochondrial cell death in human cervical cancer cells.
Kang YH; Lee SJ
J Cell Physiol; 2008 Oct; 217(1):23-33. PubMed ID: 18412143
[TBL] [Abstract][Full Text] [Related]
7. 2-Deoxy-D-glucose cooperates with arsenic trioxide to induce apoptosis in leukemia cells: involvement of IGF-1R-regulated Akt/mTOR, MEK/ERK and LKB-1/AMPK signaling pathways.
Estañ MC; Calviño E; de Blas E; Boyano-Adánez Mdel C; Mena ML; Gómez-Gómez M; Rial E; Aller P
Biochem Pharmacol; 2012 Dec; 84(12):1604-16. PubMed ID: 23041229
[TBL] [Abstract][Full Text] [Related]
8. Increased apoptotic efficacy of lonidamine plus arsenic trioxide combination in human leukemia cells. Reactive oxygen species generation and defensive protein kinase (MEK/ERK, Akt/mTOR) modulation.
Calviño E; Estañ MC; Simón GP; Sancho P; Boyano-Adánez Mdel C; de Blas E; Bréard J; Aller P
Biochem Pharmacol; 2011 Dec; 82(11):1619-29. PubMed ID: 21889928
[TBL] [Abstract][Full Text] [Related]
9. Pharmacologic inhibitors of PI3K/Akt potentiate the apoptotic action of the antileukemic drug arsenic trioxide via glutathione depletion and increased peroxide accumulation in myeloid leukemia cells.
Ramos AM; Fernández C; Amrán D; Sancho P; de Blas E; Aller P
Blood; 2005 May; 105(10):4013-20. PubMed ID: 15665116
[TBL] [Abstract][Full Text] [Related]
10. Tumor necrosis factor alpha sensitizes malignant cells to chemotherapeutic drugs via the mitochondrial apoptosis pathway independently of caspase-8 and NF-kappaB.
Schmelz K; Wieder T; Tamm I; Müller A; Essmann F; Geilen CC; Schulze-Osthoff K; Dörken B; Daniel PT
Oncogene; 2004 Sep; 23(40):6743-59. PubMed ID: 15273737
[TBL] [Abstract][Full Text] [Related]
11. Rosmarinic acid sensitizes cell death through suppression of TNF-alpha-induced NF-kappaB activation and ROS generation in human leukemia U937 cells.
Moon DO; Kim MO; Lee JD; Choi YH; Kim GY
Cancer Lett; 2010 Feb; 288(2):183-91. PubMed ID: 19619938
[TBL] [Abstract][Full Text] [Related]
12. Flavopiridol suppresses tumor necrosis factor-induced activation of activator protein-1, c-Jun N-terminal kinase, p38 mitogen-activated protein kinase (MAPK), p44/p42 MAPK, and Akt, inhibits expression of antiapoptotic gene products, and enhances apoptosis through cytochrome c release and caspase activation in human myeloid cells.
Takada Y; Sethi G; Sung B; Aggarwal BB
Mol Pharmacol; 2008 May; 73(5):1549-57. PubMed ID: 18287248
[TBL] [Abstract][Full Text] [Related]
13. Potentiation of arsenic trioxide-induced apoptosis by 8-bromo-7-methoxychrysin in human leukemia cells involves depletion of intracellular reduced glutathione.
Xiao G; Tang X; Yao C; Wang C
Acta Biochim Biophys Sin (Shanghai); 2011 Sep; 43(9):712-21. PubMed ID: 21785114
[TBL] [Abstract][Full Text] [Related]
14. Genetic deletion of PKR abrogates TNF-induced activation of IkappaBalpha kinase, JNK, Akt and cell proliferation but potentiates p44/p42 MAPK and p38 MAPK activation.
Takada Y; Ichikawa H; Pataer A; Swisher S; Aggarwal BB
Oncogene; 2007 Feb; 26(8):1201-12. PubMed ID: 16924232
[TBL] [Abstract][Full Text] [Related]
15. Combination treatment with arsenic trioxide and phytosphingosine enhances apoptotic cell death in arsenic trioxide-resistant cancer cells.
Park MT; Kang YH; Park IC; Kim CH; Lee YS; Chung HY; Lee SJ
Mol Cancer Ther; 2007 Jan; 6(1):82-92. PubMed ID: 17237268
[TBL] [Abstract][Full Text] [Related]
16. Arsenic trioxide-induced apoptosis in U937 cells involve generation of reactive oxygen species and inhibition of Akt.
Choi YJ; Park JW; Suh SI; Mun KC; Bae JH; Song DK; Kim SP; Kwon TK
Int J Oncol; 2002 Sep; 21(3):603-10. PubMed ID: 12168106
[TBL] [Abstract][Full Text] [Related]
17. Role of the p38 mitogen-activated protein kinase pathway in the generation of arsenic trioxide-dependent cellular responses.
Giafis N; Katsoulidis E; Sassano A; Tallman MS; Higgins LS; Nebreda AR; Davis RJ; Platanias LC
Cancer Res; 2006 Jul; 66(13):6763-71. PubMed ID: 16818652
[TBL] [Abstract][Full Text] [Related]
18. The novel triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO) potently enhances apoptosis induced by tumor necrosis factor in human leukemia cells.
Stadheim TA; Suh N; Ganju N; Sporn MB; Eastman A
J Biol Chem; 2002 May; 277(19):16448-55. PubMed ID: 11880365
[TBL] [Abstract][Full Text] [Related]
19. Apoptosis induced by arsenic trioxide in leukemia U937 cells is dependent on activation of p38, inactivation of ERK and the Ca2+-dependent production of superoxide.
Iwama K; Nakajo S; Aiuchi T; Nakaya K
Int J Cancer; 2001 May; 92(4):518-26. PubMed ID: 11304686
[TBL] [Abstract][Full Text] [Related]
20. p38 MAPK mediates TNF-induced apoptosis in endothelial cells via phosphorylation and downregulation of Bcl-x(L).
Grethe S; Ares MP; Andersson T; Pörn-Ares MI
Exp Cell Res; 2004 Aug; 298(2):632-42. PubMed ID: 15265709
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]