BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

388 related articles for article (PubMed ID: 17678500)

  • 1. Inhibition of the Ras oncoprotein reduces proliferation of hepatocytes in vitro and in vivo in rats.
    da Silva Morais A; Saliez A; Leclercq I; Horsmans Y; Stärkel P
    Clin Sci (Lond); 2008 Jan; 114(1):73-83. PubMed ID: 17678500
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ras inhibition in hepatocarcinoma by S-trans-trans-farnesylthiosalicyclic acid: association of its tumor preventive effect with cell proliferation, cell cycle events, and angiogenesis.
    Stärkel P; Charette N; Borbath I; Schneider-Merck T; De Saeger C; Abarca J; Leclercq I; Horsmans Y
    Mol Carcinog; 2012 Oct; 51(10):816-25. PubMed ID: 21882255
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of intimal thickening in the rat carotid artery injury model by a nontoxic Ras inhibitor.
    George J; Sack J; Barshack I; Keren P; Goldberg I; Haklai R; Elad-Sfadia G; Kloog Y; Keren G
    Arterioscler Thromb Vasc Biol; 2004 Feb; 24(2):363-8. PubMed ID: 14670932
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Ras inhibitor farnesylthiosalicylic acid as a potential therapy for neurofibromatosis type 1.
    Barkan B; Starinsky S; Friedman E; Stein R; Kloog Y
    Clin Cancer Res; 2006 Sep; 12(18):5533-42. PubMed ID: 17000690
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ethanol reduces p38 kinase activation and cyclin D1 protein expression after partial hepatectomy in rats.
    Hsu MK; Qiao L; Ho V; Zhang BH; Zhang H; Teoh N; Dent P; Farrell GC
    J Hepatol; 2006 Feb; 44(2):375-82. PubMed ID: 16226824
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The Ras inhibitor farnesylthiosalicyclic acid (FTS) prevents nodule formation and development of preneoplastic foci of altered hepatocytes in rats.
    Schneider-Merck T; Borbath I; Charette N; De Saeger C; Abarca J; Leclercq I; Horsmans Y; Stärkel P
    Eur J Cancer; 2009 Jul; 45(11):2050-60. PubMed ID: 19427195
    [TBL] [Abstract][Full Text] [Related]  

  • 7. New derivatives of farnesylthiosalicylic acid (salirasib) for cancer treatment: farnesylthiosalicylamide inhibits tumor growth in nude mice models.
    Goldberg L; Haklai R; Bauer V; Heiss A; Kloog Y
    J Med Chem; 2009 Jan; 52(1):197-205. PubMed ID: 19072665
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ras inhibition attenuates myocardial ischemia-reperfusion injury.
    Pando R; Cheporko Y; Haklai R; Maysel-Auslender S; Keren G; George J; Porat E; Sagie A; Kloog Y; Hochhauser E
    Biochem Pharmacol; 2009 May; 77(10):1593-601. PubMed ID: 19426696
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Treatment of thioacetamide-induced liver cirrhosis by the Ras antagonist, farnesylthiosalicylic acid.
    Reif S; Aeed H; Shilo Y; Reich R; Kloog Y; Kweon YO; Bruck R
    J Hepatol; 2004 Aug; 41(2):235-41. PubMed ID: 15288472
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Gene expression signature of human cancer cell lines treated with the ras inhibitor salirasib (S-farnesylthiosalicylic acid).
    Blum R; Elkon R; Yaari S; Zundelevich A; Jacob-Hirsch J; Rechavi G; Shamir R; Kloog Y
    Cancer Res; 2007 Apr; 67(7):3320-8. PubMed ID: 17409441
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ras inhibition increases the frequency and function of regulatory T cells and attenuates type-1 diabetes in non-obese diabetic mice.
    Mor A; Kloog Y; Keren G; George J
    Eur J Pharmacol; 2009 Aug; 616(1-3):301-5. PubMed ID: 19527709
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Ras inhibitor farnesylthiosalicylic acid (Salirasib) disrupts the spatiotemporal localization of active Ras: a potential treatment for cancer.
    Rotblat B; Ehrlich M; Haklai R; Kloog Y
    Methods Enzymol; 2008; 439():467-89. PubMed ID: 18374183
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Disruption of cooperation between Ras and MycN in human neuroblastoma cells promotes growth arrest.
    Yaari S; Jacob-Hirsch J; Amariglio N; Haklai R; Rechavi G; Kloog Y
    Clin Cancer Res; 2005 Jun; 11(12):4321-30. PubMed ID: 15958613
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 2-acetaminofluorene blocks cell cycle progression after hepatectomy by p21 induction and lack of cyclin E expression.
    Trautwein C; Will M; Kubicka S; Rakemann T; Flemming P; Manns MP
    Oncogene; 1999 Nov; 18(47):6443-53. PubMed ID: 10597246
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dehydroepiandrosterone causes hyperplasia and impairs regeneration in rat liver.
    Kopplow K; Wayss K; Enzmann H; Mayer D
    Int J Oncol; 2005 Dec; 27(6):1551-8. PubMed ID: 16273211
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Neoplastic hepatocyte growth associated with cyclin D1 redistribution from the cytoplasm to the nucleus in mouse hepatocarcinogenesis.
    Yamamoto M; Tamakawa S; Yoshie M; Yaginuma Y; Ogawa K
    Mol Carcinog; 2006 Dec; 45(12):901-13. PubMed ID: 17013836
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Chronic iron overload stimulates hepatocyte proliferation and cyclin D1 expression in rodent liver.
    Brown KE; Mathahs MM; Broadhurst KA; Weydert J
    Transl Res; 2006 Aug; 148(2):55-62. PubMed ID: 16890145
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of in vivo rat liver regeneration by 2-acetylaminofluorene affects the regulation of cell cycle-related proteins.
    Ohlson LC; Koroxenidou L; Hällström IP
    Hepatology; 1998 Mar; 27(3):691-6. PubMed ID: 9500696
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Loss of NF-kappaB activation in Kupffer cell-depleted mice impairs liver regeneration after partial hepatectomy.
    Abshagen K; Eipel C; Kalff JC; Menger MD; Vollmar B
    Am J Physiol Gastrointest Liver Physiol; 2007 Jun; 292(6):G1570-7. PubMed ID: 17322066
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 3-Deazaadenosine prevents smooth muscle cell proliferation and neointima formation by interfering with Ras signaling.
    Sedding DG; Tröbs M; Reich F; Walker G; Fink L; Haberbosch W; Rau W; Tillmanns H; Preissner KT; Bohle RM; Langheinrich AC
    Circ Res; 2009 May; 104(10):1192-200. PubMed ID: 19372464
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.