BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

538 related articles for article (PubMed ID: 17678648)

  • 1. rAAV-mediated nigral human parkin over-expression partially ameliorates motor deficits via enhanced dopamine neurotransmission in a rat model of Parkinson's disease.
    Manfredsson FP; Burger C; Sullivan LF; Muzyczka N; Lewin AS; Mandel RJ
    Exp Neurol; 2007 Oct; 207(2):289-301. PubMed ID: 17678648
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeted overexpression of the parkin substrate Pael-R in the nigrostriatal system of adult rats to model Parkinson's disease.
    Dusonchet J; Bensadoun JC; Schneider BL; Aebischer P
    Neurobiol Dis; 2009 Jul; 35(1):32-41. PubMed ID: 19348945
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The role of parkin in the differential susceptibility of tuberoinfundibular and nigrostriatal dopamine neurons to acute toxicant exposure.
    Benskey MJ; Manfredsson FP; Lookingland KJ; Goudreau JL
    Neurotoxicology; 2015 Jan; 46():1-11. PubMed ID: 25447324
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Parkin protects against neurotoxicity in the 6-hydroxydopamine rat model for Parkinson's disease.
    Vercammen L; Van der Perren A; Vaudano E; Gijsbers R; Debyser Z; Van den Haute C; Baekelandt V
    Mol Ther; 2006 Nov; 14(5):716-23. PubMed ID: 16914382
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Delayed gene therapy of glial cell line-derived neurotrophic factor is efficacious in a rat model of Parkinson's disease.
    Zheng JS; Tang LL; Zheng SS; Zhan RY; Zhou YQ; Goudreau J; Kaufman D; Chen AF
    Brain Res Mol Brain Res; 2005 Mar; 134(1):155-61. PubMed ID: 15790539
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Continuous low-level glial cell line-derived neurotrophic factor delivery using recombinant adeno-associated viral vectors provides neuroprotection and induces behavioral recovery in a primate model of Parkinson's disease.
    Eslamboli A; Georgievska B; Ridley RM; Baker HF; Muzyczka N; Burger C; Mandel RJ; Annett L; Kirik D
    J Neurosci; 2005 Jan; 25(4):769-77. PubMed ID: 15673656
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Forelimb akinesia in the rat Parkinson model: differential effects of dopamine agonists and nigral transplants as assessed by a new stepping test.
    Olsson M; Nikkhah G; Bentlage C; Björklund A
    J Neurosci; 1995 May; 15(5 Pt 2):3863-75. PubMed ID: 7751951
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Aberrant sprouting and downregulation of tyrosine hydroxylase in lesioned nigrostriatal dopamine neurons induced by long-lasting overexpression of glial cell line derived neurotrophic factor in the striatum by lentiviral gene transfer.
    Georgievska B; Kirik D; Björklund A
    Exp Neurol; 2002 Oct; 177(2):461-74. PubMed ID: 12429192
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Differential effects of glial cell line-derived neurotrophic factor (GDNF) in the striatum and substantia nigra of the aged Parkinsonian rat.
    Connor B; Kozlowski DA; Schallert T; Tillerson JL; Davidson BL; Bohn MC
    Gene Ther; 1999 Dec; 6(12):1936-51. PubMed ID: 10637445
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Recombinant adeno-associated viral vector-mediated glial cell line-derived neurotrophic factor gene transfer protects nigral dopamine neurons after onset of progressive degeneration in a rat model of Parkinson's disease.
    Mandel RJ; Snyder RO; Leff SE
    Exp Neurol; 1999 Nov; 160(1):205-14. PubMed ID: 10630205
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Midbrain injection of recombinant adeno-associated virus encoding rat glial cell line-derived neurotrophic factor protects nigral neurons in a progressive 6-hydroxydopamine-induced degeneration model of Parkinson's disease in rats.
    Mandel RJ; Spratt SK; Snyder RO; Leff SE
    Proc Natl Acad Sci U S A; 1997 Dec; 94(25):14083-8. PubMed ID: 9391156
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Delivery of a GDNF gene into the substantia nigra after a progressive 6-OHDA lesion maintains functional nigrostriatal connections.
    Kozlowski DA; Connor B; Tillerson JL; Schallert T; Bohn MC
    Exp Neurol; 2000 Nov; 166(1):1-15. PubMed ID: 11031079
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Impaired acquisition of skilled behavior in rotarod task by moderate depletion of striatal dopamine in a pre-symptomatic stage model of Parkinson's disease.
    Ogura T; Ogata M; Akita H; Jitsuki S; Akiba L; Noda K; Hoka S; Saji M
    Neurosci Res; 2005 Mar; 51(3):299-308. PubMed ID: 15710494
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Delayed delivery of AAV-GDNF prevents nigral neurodegeneration and promotes functional recovery in a rat model of Parkinson's disease.
    Wang L; Muramatsu S; Lu Y; Ikeguchi K; Fujimoto K; Okada T; Mizukami H; Hanazono Y; Kume A; Urano F; Ichinose H; Nagatsu T; Nakano I; Ozawa K
    Gene Ther; 2002 Mar; 9(6):381-9. PubMed ID: 11960314
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Overexpression of parkin in the rat nigrostriatal dopamine system protects against methamphetamine neurotoxicity.
    Liu B; Traini R; Killinger B; Schneider B; Moszczynska A
    Exp Neurol; 2013 Sep; 247():359-72. PubMed ID: 23313192
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Adenoviral vector-mediated GDNF gene therapy in a rodent lesion model of late stage Parkinson's disease.
    Lapchak PA; Araujo DM; Hilt DC; Sheng J; Jiao S
    Brain Res; 1997 Nov; 777(1-2):153-60. PubMed ID: 9449424
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sequential administration of GDNF into the substantia nigra and striatum promotes dopamine neuron survival and axonal sprouting but not striatal reinnervation or functional recovery in the partial 6-OHDA lesion model.
    Rosenblad C; Kirik D; Björklund A
    Exp Neurol; 2000 Feb; 161(2):503-16. PubMed ID: 10686072
    [TBL] [Abstract][Full Text] [Related]  

  • 18. GFR-α1 Expression in Substantia Nigra Increases Bilaterally Following Unilateral Striatal GDNF in Aged Rats and Attenuates Nigral Tyrosine Hydroxylase Loss Following 6-OHDA Nigrostriatal Lesion.
    Kasanga EA; Owens CL; Cantu MA; Richard AD; Davis RW; McDivitt LM; Blancher B; Pruett BS; Tan C; Gajewski A; Manfredsson FP; Nejtek VA; Salvatore MF
    ACS Chem Neurosci; 2019 Oct; 10(10):4237-4249. PubMed ID: 31538765
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ser31 Tyrosine hydroxylase phosphorylation parallels differences in dopamine recovery in nigrostriatal pathway following 6-OHDA lesion.
    Salvatore MF
    J Neurochem; 2014 May; 129(3):548-58. PubMed ID: 24410633
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Intranigral lentiviral delivery of dominant-negative TNF attenuates neurodegeneration and behavioral deficits in hemiparkinsonian rats.
    McCoy MK; Ruhn KA; Martinez TN; McAlpine FE; Blesch A; Tansey MG
    Mol Ther; 2008 Sep; 16(9):1572-9. PubMed ID: 18628756
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 27.