BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

165 related articles for article (PubMed ID: 17682092)

  • 1. Evidence for a role of superoxide generation in glucose-induced beta-cell dysfunction in vivo.
    Tang C; Han P; Oprescu AI; Lee SC; Gyulkhandanyan AV; Chan GN; Wheeler MB; Giacca A
    Diabetes; 2007 Nov; 56(11):2722-31. PubMed ID: 17682092
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Glucose-induced beta cell dysfunction in vivo in rats: link between oxidative stress and endoplasmic reticulum stress.
    Tang C; Koulajian K; Schuiki I; Zhang L; Desai T; Ivovic A; Wang P; Robson-Doucette C; Wheeler MB; Minassian B; Volchuk A; Giacca A
    Diabetologia; 2012 May; 55(5):1366-79. PubMed ID: 22396011
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Free fatty acid-induced reduction in glucose-stimulated insulin secretion: evidence for a role of oxidative stress in vitro and in vivo.
    Oprescu AI; Bikopoulos G; Naassan A; Allister EM; Tang C; Park E; Uchino H; Lewis GF; Fantus IG; Rozakis-Adcock M; Wheeler MB; Giacca A
    Diabetes; 2007 Dec; 56(12):2927-37. PubMed ID: 17717282
    [TBL] [Abstract][Full Text] [Related]  

  • 4. NADPH oxidase inhibition prevents beta cell dysfunction induced by prolonged elevation of oleate in rodents.
    Koulajian K; Desai T; Liu GC; Ivovic A; Patterson JN; Tang C; El-Benna J; Joseph JW; Scholey JW; Giacca A
    Diabetologia; 2013 May; 56(5):1078-87. PubMed ID: 23429921
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Antioxidants N-acetyl-L-cysteine and manganese(III)tetrakis (4-benzoic acid)porphyrin do not prevent beta-cell dysfunction in rat islets cultured in high glucose for 1 wk.
    Khaldi MZ; Elouil H; Guiot Y; Henquin JC; Jonas JC
    Am J Physiol Endocrinol Metab; 2006 Jul; 291(1):E137-46. PubMed ID: 16464909
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Overexpression of glutathione peroxidase 4 prevents β-cell dysfunction induced by prolonged elevation of lipids in vivo.
    Koulajian K; Ivovic A; Ye K; Desai T; Shah A; Fantus IG; Ran Q; Giacca A
    Am J Physiol Endocrinol Metab; 2013 Jul; 305(2):E254-62. PubMed ID: 23695217
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Glucose-Dependent Insulin Secretion in Pancreatic β-Cell Islets from Male Rats Requires Ca2+ Release via ROS-Stimulated Ryanodine Receptors.
    Llanos P; Contreras-Ferrat A; Barrientos G; Valencia M; Mears D; Hidalgo C
    PLoS One; 2015; 10(6):e0129238. PubMed ID: 26046640
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Glucose-Induced β-Cell Dysfunction In Vivo: Evidence for a Causal Role of C-jun N-terminal Kinase Pathway.
    Tang C; Yeung LSN; Koulajian K; Zhang L; Tai K; Volchuk A; Giacca A
    Endocrinology; 2018 Nov; 159(11):3643-3654. PubMed ID: 30215691
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Acute intravenous glucose load impairs early insulin secretion and insulin content in islet β cells in mice.
    Yan D; Zhao Y; Gao X; Zhou Y
    Life Sci; 2016 Jan; 144():148-55. PubMed ID: 26674463
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The impairment of glucose-stimulated insulin secretion in pancreatic β-cells caused by prolonged glucotoxicity and lipotoxicity is associated with elevated adaptive antioxidant response.
    Fu J; Cui Q; Yang B; Hou Y; Wang H; Xu Y; Wang D; Zhang Q; Pi J
    Food Chem Toxicol; 2017 Feb; 100():161-167. PubMed ID: 28027979
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Omega-3 supplementation improves pancreatic islet redox status: in vivo and in vitro studies.
    Lucena CF; Roma LP; Graciano MF; Veras K; Simões D; Curi R; Carpinelli AR
    Pancreas; 2015 Mar; 44(2):287-95. PubMed ID: 25426612
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mitochondrial reactive oxygen species are obligatory signals for glucose-induced insulin secretion.
    Leloup C; Tourrel-Cuzin C; Magnan C; Karaca M; Castel J; Carneiro L; Colombani AL; Ktorza A; Casteilla L; Pénicaud L
    Diabetes; 2009 Mar; 58(3):673-81. PubMed ID: 19073765
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mitochondrial oxidative stress mediates high-phosphate-induced secretory defects and apoptosis in insulin-secreting cells.
    Nguyen TT; Quan X; Hwang KH; Xu S; Das R; Choi SK; Wiederkehr A; Wollheim CB; Cha SK; Park KS
    Am J Physiol Endocrinol Metab; 2015 Jun; 308(11):E933-41. PubMed ID: 25852001
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dietary copper supplementation restores β-cell function of Cohen diabetic rats: a link between mitochondrial function and glucose-stimulated insulin secretion.
    Weksler-Zangen S; Jörns A; Tarsi-Chen L; Vernea F; Aharon-Hananel G; Saada A; Lenzen S; Raz I
    Am J Physiol Endocrinol Metab; 2013 May; 304(10):E1023-34. PubMed ID: 23512809
    [TBL] [Abstract][Full Text] [Related]  

  • 15. IKKβ inhibition prevents fat-induced beta cell dysfunction in vitro and in vivo in rodents.
    Ivovic A; Oprescu AI; Koulajian K; Mori Y; Eversley JA; Zhang L; Nino-Fong R; Lewis GF; Donath MY; Karin M; Wheeler MB; Ehses J; Volchuk A; Chan CB; Giacca A
    Diabetologia; 2017 Oct; 60(10):2021-2032. PubMed ID: 28725915
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mitochondrial oxidative stress contributes differently to rat pancreatic islet cell apoptosis and insulin secretory defects after prolonged culture in a low non-stimulating glucose concentration.
    Roma LP; Pascal SM; Duprez J; Jonas JC
    Diabetologia; 2012 Aug; 55(8):2226-37. PubMed ID: 22643931
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The role of phosphoinositide 3-kinase/Akt signaling in low-dose mercury-induced mouse pancreatic beta-cell dysfunction in vitro and in vivo.
    Chen YW; Huang CF; Tsai KS; Yang RS; Yen CC; Yang CY; Lin-Shiau SY; Liu SH
    Diabetes; 2006 Jun; 55(6):1614-24. PubMed ID: 16731823
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tributyltin exposure at noncytotoxic doses dysregulates pancreatic β-cell function in vitro and in vivo.
    Chen YW; Lan KC; Tsai JR; Weng TI; Yang CY; Liu SH
    Arch Toxicol; 2017 Sep; 91(9):3135-3144. PubMed ID: 28180948
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mitochondrial succinate dehydrogenase is involved in stimulus-secretion coupling and endogenous ROS formation in murine beta cells.
    Edalat A; Schulte-Mecklenbeck P; Bauer C; Undank S; Krippeit-Drews P; Drews G; Düfer M
    Diabetologia; 2015 Jul; 58(7):1532-41. PubMed ID: 25874444
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PPARalpha activation reverses adverse effects induced by high-saturated-fat feeding on pancreatic beta-cell function in late pregnancy.
    Holness MJ; Smith ND; Greenwood GK; Sugden MC
    Am J Physiol Endocrinol Metab; 2007 Apr; 292(4):E1087-94. PubMed ID: 17164438
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.