These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

205 related articles for article (PubMed ID: 1768258)

  • 1. Antifolates induce primary inhibition of the de novo purine pathway prior to 5-aminoimidazole-4-carboxamide ribotide transformylase in leukemia cells.
    Lyons SD; Christopherson RI
    Biochem Int; 1991 May; 24(1):187-97. PubMed ID: 1768258
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Antifolates induce inhibition of amido phosphoribosyltransferase in leukemia cells.
    Sant ME; Lyons SD; Phillips L; Christopherson RI
    J Biol Chem; 1992 Jun; 267(16):11038-45. PubMed ID: 1597445
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dual effects of pyrazofurin and 3-deazauridine upon pyrimidine and purine biosynthesis in mouse L1210 leukemia.
    Sant ME; Lyons SD; Kemp AJ; McClure LK; Szabados E; Christopherson RI
    Cancer Res; 1989 May; 49(10):2645-50. PubMed ID: 2713848
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Biochemical and biological studies on 2-desamino-2-methylaminopterin, an antifolate the polyglutamates of which are more potent than the monoglutamate against three key enzymes of folate metabolism.
    Rosowsky A; Galivan J; Beardsley GP; Bader H; O'Connor BM; Russello O; Moroson BA; DeYarman MT; Kerwar SS; Freisheim JH
    Cancer Res; 1992 Apr; 52(8):2148-55. PubMed ID: 1313737
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of 5-aminoimidazole-4-carboxamide ribotide transformylase, adenosine deaminase and 5'-adenylate deaminase by polyglutamates of methotrexate and oxidized folates and by 5-aminoimidazole-4-carboxamide riboside and ribotide.
    Baggott JE; Vaughn WH; Hudson BB
    Biochem J; 1986 May; 236(1):193-200. PubMed ID: 2431676
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evidence for direct inhibition of de novo purine synthesis in human MCF-7 breast cells as a principal mode of metabolic inhibition by methotrexate.
    Allegra CJ; Hoang K; Yeh GC; Drake JC; Baram J
    J Biol Chem; 1987 Oct; 262(28):13520-6. PubMed ID: 2443493
    [TBL] [Abstract][Full Text] [Related]  

  • 7. LY231514, a pyrrolo[2,3-d]pyrimidine-based antifolate that inhibits multiple folate-requiring enzymes.
    Shih C; Chen VJ; Gossett LS; Gates SB; MacKellar WC; Habeck LL; Shackelford KA; Mendelsohn LG; Soose DJ; Patel VF; Andis SL; Bewley JR; Rayl EA; Moroson BA; Beardsley GP; Kohler W; Ratnam M; Schultz RM
    Cancer Res; 1997 Mar; 57(6):1116-23. PubMed ID: 9067281
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Antifolates in rheumatoid arthritis: a hypothetical mechanism of action.
    Baggott JE; Morgan SL; Ha TS; Alarcón GS; Koopman WJ; Krumdieck CL
    Clin Exp Rheumatol; 1993; 11 Suppl 8():S101-5. PubMed ID: 8324932
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification and biochemical properties of 10-formyldihydrofolate, a novel folate found in methotrexate-treated cells.
    Baram J; Chabner BA; Drake JC; Fitzhugh AL; Sholar PW; Allegra CJ
    J Biol Chem; 1988 May; 263(15):7105-11. PubMed ID: 3366769
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The effect of methotrexate and 7-hydroxymethotrexate on rat adjuvant arthritis and on urinary aminoimidazole carboxamide excretion.
    Baggott JE; Morgan SL; Koopman WJ
    Arthritis Rheum; 1998 Aug; 41(8):1407-10. PubMed ID: 9704638
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Chromatographic analysis of purine precursors in mouse L1210 leukemia.
    Sant ME; Poiner A; Harsanyi MC; Lyons SD; Christopherson RI
    Anal Biochem; 1989 Oct; 182(1):121-8. PubMed ID: 2604037
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 5-Aminoimidazole-4-carboxamide ribotide transformylase-IMP cyclohydrolase from human CCRF-CEM leukemia cells: purification, pH dependence, and inhibitors.
    Szabados E; Hindmarsh EJ; Phillips L; Duggleby RG; Christopherson RI
    Biochemistry; 1994 Nov; 33(47):14237-45. PubMed ID: 7947835
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel pyrrolo[2,3-d]pyrimidine antifolate TNP-351: cytotoxic effect on methotrexate-resistant CCRF-CEM cells and inhibition of transformylases of de novo purine biosynthesis.
    Itoh F; Russello O; Akimoto H; Beardsley GP
    Cancer Chemother Pharmacol; 1994; 34(4):273-9. PubMed ID: 8033293
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Radioassay of bifunctional 5-aminoimidazole-4-carboxamide ribotide transformylase-IMP cyclohydrolase by thin-layer chromatography.
    Szabados E; Christopherson RI
    Anal Biochem; 1994 Sep; 221(2):401-4. PubMed ID: 7810885
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Multifactorial resistance to 5,10-dideazatetrahydrofolic acid in cell lines derived from human lymphoblastic leukemia CCRF-CEM.
    Pizzorno G; Moroson BA; Cashmore AR; Russello O; Mayer JR; Galivan J; Bunni MA; Priest DG; Beardsley GP
    Cancer Res; 1995 Feb; 55(3):566-73. PubMed ID: 7834626
    [TBL] [Abstract][Full Text] [Related]  

  • 16. On the cofactor specificity of glycinamide ribonucleotide and 5-aminoimidazole-4-carboxamide ribonucleotide transformylase from chicken liver.
    Smith GK; Mueller WT; Benkovic PA; Benkovic SJ
    Biochemistry; 1981 Mar; 20(5):1241-5. PubMed ID: 7225325
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Induction of HL-60 leukemia cell differentiation by the novel antifolate 5,10-dideazatetrahydrofolic acid.
    Sokoloski JA; Beardsley GP; Sartorelli AC
    Cancer Res; 1989 Sep; 49(17):4824-8. PubMed ID: 2758415
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differences in methotrexate and 7-hydroxymethotrexate inhibition of folate-dependent enzymes of purine nucleotide biosynthesis.
    Baggott JE; Morgan SL; Vaughn WH
    Biochem J; 1994 Jun; 300 ( Pt 3)(Pt 3):627-9. PubMed ID: 8010943
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and antifolate activity of 5-methyl-5,10-dideaza analogues of aminopterin and folic acid and an alternative synthesis of 5,10-dideazatetrahydrofolic acid, a potent inhibitor of glycinamide ribonucleotide formyltransferase.
    Piper JR; McCaleb GS; Montgomery JA; Kisliuk RL; Gaumont Y; Thorndike J; Sirotnak FM
    J Med Chem; 1988 Nov; 31(11):2164-9. PubMed ID: 3184124
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and biological activity of an acyclic analogue of 5,6,7,8-tetrahydrofolic acid, N-[4-[[3-(2,4-diamino-1,6-dihydro-6-oxo-5- pyrimidinyl)propyl]amino]-benzoyl]-L-glutamic acid.
    Kelley JL; McLean EW; Cohn NK; Edelstein MP; Duch DS; Smith GK; Hanlon MH; Ferone R
    J Med Chem; 1990 Feb; 33(2):561-7. PubMed ID: 2299624
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.