These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

123 related articles for article (PubMed ID: 17683929)

  • 1. Regulation of estrogen receptor (ER) levels in MCF-7 cells by progesterone metabolites.
    Pawlak KJ; Wiebe JP
    J Steroid Biochem Mol Biol; 2007; 107(3-5):172-9. PubMed ID: 17683929
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Membrane 5alpha-pregnane-3,20-dione (5alphaP) receptors in MCF-7 and MCF-10A breast cancer cells are up-regulated by estradiol and 5alphaP and down-regulated by the progesterone metabolites, 3alpha-dihydroprogesterone and 20alpha-dihydroprogesterone, with associated changes in cell proliferation and detachment.
    Pawlak KJ; Zhang G; Wiebe JP
    J Steroid Biochem Mol Biol; 2005 Nov; 97(3):278-88. PubMed ID: 16154741
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Plasma membrane receptors for the cancer-regulating progesterone metabolites, 5alpha-pregnane-3,20-dione and 3alpha-hydroxy-4-pregnen-20-one in MCF-7 breast cancer cells.
    Weiler PJ; Wiebe JP
    Biochem Biophys Res Commun; 2000 Jun; 272(3):731-7. PubMed ID: 10860824
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Progesterone metabolites regulate induction, growth, and suppression of estrogen- and progesterone receptor-negative human breast cell tumors.
    Wiebe JP; Zhang G; Welch I; Cadieux-Pitre HA
    Breast Cancer Res; 2013 May; 15(3):R38. PubMed ID: 25927181
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The 4-pregnene and 5alpha-pregnane progesterone metabolites formed in nontumorous and tumorous breast tissue have opposite effects on breast cell proliferation and adhesion.
    Wiebe JP; Muzia D; Hu J; Szwajcer D; Hill SA; Seachrist JL
    Cancer Res; 2000 Feb; 60(4):936-43. PubMed ID: 10706108
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Opposing actions of the progesterone metabolites, 5alpha-dihydroprogesterone (5alphaP) and 3alpha-dihydroprogesterone (3alphaHP) on mitosis, apoptosis, and expression of Bcl-2, Bax and p21 in human breast cell lines.
    Wiebe JP; Beausoleil M; Zhang G; Cialacu V
    J Steroid Biochem Mol Biol; 2010 Jan; 118(1-2):125-32. PubMed ID: 19931389
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Progesterone metabolites in breast cancer.
    Wiebe JP
    Endocr Relat Cancer; 2006 Sep; 13(3):717-38. PubMed ID: 16954427
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dutasteride affects progesterone metabolizing enzyme activity/expression in human breast cell lines resulting in suppression of cell proliferation and detachment.
    Wiebe JP; Souter L; Zhang G
    J Steroid Biochem Mol Biol; 2006 Aug; 100(4-5):129-40. PubMed ID: 16806904
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Expression of progesterone metabolizing enzyme genes (AKR1C1, AKR1C2, AKR1C3, SRD5A1, SRD5A2) is altered in human breast carcinoma.
    Lewis MJ; Wiebe JP; Heathcote JG
    BMC Cancer; 2004 Jun; 4():27. PubMed ID: 15212687
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mechanism of action of the breast cancer-promoter hormone, 5α-dihydroprogesterone (5αP), involves plasma membrane-associated receptors and MAPK activation.
    Wiebe JP; Pawlak KJ; Kwok A
    J Steroid Biochem Mol Biol; 2016 Jan; 155(Pt A):166-76. PubMed ID: 26519986
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis, metabolism and levels of the neuroactive steroid, 3alpha-hydroxy-4-pregnen-20-one (3alphaHP), in rat pituitaries.
    Wiebe JP; Boushy D; Wolfe M
    Brain Res; 1997 Aug; 764(1-2):158-66. PubMed ID: 9295205
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Progesterone-induced stimulation of mammary tumorigenesis is due to the progesterone metabolite, 5α-dihydroprogesterone (5αP) and can be suppressed by the 5α-reductase inhibitor, finasteride.
    Wiebe JP; Rivas MA; Mercogliano MF; Elizalde PV; Schillaci R
    J Steroid Biochem Mol Biol; 2015 May; 149():27-34. PubMed ID: 25595041
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 1alpha,25-Dihydroxyvitamin D3 down-regulates estrogen receptor abundance and suppresses estrogen actions in MCF-7 human breast cancer cells.
    Swami S; Krishnan AV; Feldman D
    Clin Cancer Res; 2000 Aug; 6(8):3371-9. PubMed ID: 10955825
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The role of progesterone metabolites in breast cancer: potential for new diagnostics and therapeutics.
    Wiebe JP; Lewis MJ; Cialacu V; Pawlak KJ; Zhang G
    J Steroid Biochem Mol Biol; 2005 Feb; 93(2-5):201-8. PubMed ID: 15860263
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Activity and expression of progesterone metabolizing 5alpha-reductase, 20alpha-hydroxysteroid oxidoreductase and 3alpha(beta)-hydroxysteroid oxidoreductases in tumorigenic (MCF-7, MDA-MB-231, T-47D) and nontumorigenic (MCF-10A) human breast cancer cells.
    Wiebe JP; Lewis MJ
    BMC Cancer; 2003 Mar; 3():9. PubMed ID: 12659654
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The endogenous progesterone metabolite, 5a-pregnane-3,20-dione, decreases cell-substrate attachment, adhesion plaques, vinculin expression, and polymerized F-actin in MCF-7 breast cancer cells.
    Wiebe JP; Muzia D
    Endocrine; 2001 Oct; 16(1):7-14. PubMed ID: 11822829
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Estrogenic activity of a dieldrin/toxaphene mixture in the mouse uterus, MCF-7 human breast cancer cells, and yeast-based estrogen receptor assays: no apparent synergism.
    Ramamoorthy K; Wang F; Chen IC; Norris JD; McDonnell DP; Leonard LS; Gaido KW; Bocchinfuso WP; Korach KS; Safe S
    Endocrinology; 1997 Apr; 138(4):1520-7. PubMed ID: 9075711
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Reproducibility of an assay to measure serum progesterone metabolites that may be related to breast cancer risk using liquid chromatography-tandem mass spectrometry.
    Trabert B; Falk RT; Stanczyk FZ; McGlynn KA; Brinton LA; Xu X
    Horm Mol Biol Clin Investig; 2015 Sep; 23(3):79-84. PubMed ID: 26353176
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Gene regulation in an MCF-7 cell line that naturally expresses an estrogen receptor unable to directly bind DNA.
    Pentecost BT; Bradley LM; Gierthy JF; Ding Y; Fasco MJ
    Mol Cell Endocrinol; 2005 Jun; 238(1-2):9-25. PubMed ID: 15913882
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mitogenic estrogen metabolites alter the expression of 17beta-estradiol-regulated proteins including heat shock proteins in human MCF-7 breast cancer cells.
    Kim SH; Lee SU; Kim MH; Kim BT; Min YK
    Mol Cells; 2005 Dec; 20(3):378-84. PubMed ID: 16404153
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.