BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

227 related articles for article (PubMed ID: 17685560)

  • 1. Phenylthiazolyl-hydrazide and its derivatives are potent inhibitors of tau aggregation and toxicity in vitro and in cells.
    Pickhardt M; Larbig G; Khlistunova I; Coksezen A; Meyer B; Mandelkow EM; Schmidt B; Mandelkow E
    Biochemistry; 2007 Sep; 46(35):10016-23. PubMed ID: 17685560
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The natively unfolded character of tau and its aggregation to Alzheimer-like paired helical filaments.
    Jeganathan S; von Bergen M; Mandelkow EM; Mandelkow E
    Biochemistry; 2008 Oct; 47(40):10526-39. PubMed ID: 18783251
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Screening for inhibitors of tau protein aggregation into Alzheimer paired helical filaments: a ligand based approach results in successful scaffold hopping.
    Larbig G; Pickhardt M; Lloyd DG; Schmidt B; Mandelkow E
    Curr Alzheimer Res; 2007 Jul; 4(3):315-23. PubMed ID: 17627489
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Possible role of each repeat structure of the microtubule-binding domain of the tau protein in in vitro aggregation.
    Tomoo K; Yao TM; Minoura K; Hiraoka S; Sumida M; Taniguchi T; Ishida T
    J Biochem; 2005 Oct; 138(4):413-23. PubMed ID: 16272135
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural impact of heparin binding to full-length Tau as studied by NMR spectroscopy.
    Sibille N; Sillen A; Leroy A; Wieruszeski JM; Mulloy B; Landrieu I; Lippens G
    Biochemistry; 2006 Oct; 45(41):12560-72. PubMed ID: 17029411
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tau paired helical filaments from Alzheimer's disease brain and assembled in vitro are based on beta-structure in the core domain.
    Barghorn S; Davies P; Mandelkow E
    Biochemistry; 2004 Feb; 43(6):1694-703. PubMed ID: 14769047
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Disaggregation of tau as a therapeutic approach to tauopathies.
    Duff K; Kuret J; Congdon EE
    Curr Alzheimer Res; 2010 May; 7(3):235-40. PubMed ID: 20088807
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecules of the quinoline family block tau self-aggregation: implications toward a therapeutic approach for Alzheimer's disease.
    Navarrete LP; Guzmán L; San Martín A; Astudillo-Saavedra L; Maccioni RB
    J Alzheimers Dis; 2012; 29(1):79-88. PubMed ID: 22232002
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Development of tau aggregation inhibitors for Alzheimer's disease.
    Bulic B; Pickhardt M; Schmidt B; Mandelkow EM; Waldmann H; Mandelkow E
    Angew Chem Int Ed Engl; 2009; 48(10):1740-52. PubMed ID: 19189357
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Anthraquinones inhibit tau aggregation and dissolve Alzheimer's paired helical filaments in vitro and in cells.
    Pickhardt M; Gazova Z; von Bergen M; Khlistunova I; Wang Y; Hascher A; Mandelkow EM; Biernat J; Mandelkow E
    J Biol Chem; 2005 Feb; 280(5):3628-35. PubMed ID: 15525637
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Granular tau oligomers as intermediates of tau filaments.
    Maeda S; Sahara N; Saito Y; Murayama M; Yoshiike Y; Kim H; Miyasaka T; Murayama S; Ikai A; Takashima A
    Biochemistry; 2007 Mar; 46(12):3856-61. PubMed ID: 17338548
    [TBL] [Abstract][Full Text] [Related]  

  • 12. X-ray structure of the PHF core C-terminus: insight into the folding of the intrinsically disordered protein tau in Alzheimer's disease.
    Sevcik J; Skrabana R; Dvorsky R; Csokova N; Iqbal K; Novak M
    FEBS Lett; 2007 Dec; 581(30):5872-8. PubMed ID: 18061582
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Amyloid-dependent triosephosphate isomerase nitrotyrosination induces glycation and tau fibrillation.
    Guix FX; Ill-Raga G; Bravo R; Nakaya T; de Fabritiis G; Coma M; Miscione GP; Villà-Freixa J; Suzuki T; Fernàndez-Busquets X; Valverde MA; de Strooper B; Muñoz FJ
    Brain; 2009 May; 132(Pt 5):1335-45. PubMed ID: 19251756
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Alzheimer's-disease-associated conformation of intrinsically disordered tau protein studied by intrinsically disordered protein liquid-phase competitive enzyme-linked immunosorbent assay.
    Skrabana R; Skrabanova-Khuebachova M; Kontsek P; Novak M
    Anal Biochem; 2006 Dec; 359(2):230-7. PubMed ID: 17081491
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Understanding the disrupting mechanism of the Tau aggregation motif "
    Moreno-Castillo E; Álvarez-Ginarte YM; Valdés-Tresanco ME; Montero-Cabrera LA; Moreno E; Valiente PA
    J Mol Recognit; 2020 Sep; 33(9):e2848. PubMed ID: 32227525
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tau aggregation followed by atomic force microscopy and surface plasmon resonance, and single molecule tau-tau interaction probed by atomic force spectroscopy.
    Barrantes A; Sotres J; Hernando-Pérez M; Benítez MJ; de Pablo PJ; Baró AM; Avila J; Jiménez JS
    J Alzheimers Dis; 2009; 18(1):141-51. PubMed ID: 19625749
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cyanine dye N744 inhibits tau fibrillization by blocking filament extension: implications for the treatment of tauopathic neurodegenerative diseases.
    Necula M; Chirita CN; Kuret J
    Biochemistry; 2005 Aug; 44(30):10227-37. PubMed ID: 16042400
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Taurine, an inducer for tau polymerization and a weak inhibitor for amyloid-beta-peptide aggregation.
    Santa-María I; Hernández F; Moreno FJ; Avila J
    Neurosci Lett; 2007 Dec; 429(2-3):91-4. PubMed ID: 17976912
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Copper binding properties of a tau peptide associated with Alzheimer's disease studied by CD, NMR, and MALDI-TOF MS.
    Ma Q; Li Y; Du J; Liu H; Kanazawa K; Nemoto T; Nakanishi H; Zhao Y
    Peptides; 2006 Apr; 27(4):841-9. PubMed ID: 16225961
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Nitration and oligomerization of tau induced by peroxynitrite inhibit its microtubule-binding activity.
    Zhang YJ; Xu YF; Chen XQ; Wang XC; Wang JZ
    FEBS Lett; 2005 Apr; 579(11):2421-7. PubMed ID: 15848182
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.