BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

343 related articles for article (PubMed ID: 17693551)

  • 1. Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator.
    Perry M; Sachse FB; Sanguinetti MC
    Proc Natl Acad Sci U S A; 2007 Aug; 104(34):13827-32. PubMed ID: 17693551
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A single amino acid difference between ether-a-go-go- related gene channel subtypes determines differential sensitivity to a small molecule activator.
    Perry M; Sanguinetti MC
    Mol Pharmacol; 2008 Apr; 73(4):1044-51. PubMed ID: 18162604
    [TBL] [Abstract][Full Text] [Related]  

  • 3. C-Linker Accounts for Differential Sensitivity of ERG1 and ERG2 K+ Channels to RPR260243-Induced Slow Deactivation.
    Gardner A; Sanguinetti MC
    Mol Pharmacol; 2015 Jul; 88(1):19-28. PubMed ID: 25888115
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Concatenated hERG1 tetramers reveal stoichiometry of altered channel gating by RPR-260243.
    Wu W; Gardner A; Sanguinetti MC
    Mol Pharmacol; 2015; 87(3):401-9. PubMed ID: 25519838
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PD-118057 contacts the pore helix of hERG1 channels to attenuate inactivation and enhance K+ conductance.
    Perry M; Sachse FB; Abbruzzese J; Sanguinetti MC
    Proc Natl Acad Sci U S A; 2009 Nov; 106(47):20075-80. PubMed ID: 19892732
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular determinants of human ether-à-go-go-related gene 1 (hERG1) K+ channel activation by NS1643.
    Grunnet M; Abbruzzese J; Sachse FB; Sanguinetti MC
    Mol Pharmacol; 2011 Jan; 79(1):1-9. PubMed ID: 20876384
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery of a small molecule activator of the human ether-a-go-go-related gene (HERG) cardiac K+ channel.
    Kang J; Chen XL; Wang H; Ji J; Cheng H; Incardona J; Reynolds W; Viviani F; Tabart M; Rampe D
    Mol Pharmacol; 2005 Mar; 67(3):827-36. PubMed ID: 15548764
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular Basis of Altered hERG1 Channel Gating Induced by Ginsenoside Rg3.
    Gardner A; Wu W; Thomson S; Zangerl-Plessl EM; Stary-Weinzinger A; Sanguinetti MC
    Mol Pharmacol; 2017 Oct; 92(4):437-450. PubMed ID: 28705808
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Binding of RPR260243 at the intracellular side of the hERG1 channel pore domain slows closure of the helix bundle crossing gate.
    Zangerl-Plessl EM; Wu W; Sanguinetti MC; Stary-Weinzinger A
    Front Mol Biosci; 2023; 10():1137368. PubMed ID: 36911523
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Modification of hERG1 channel gating by Cd2+.
    Abbruzzese J; Sachse FB; Tristani-Firouzi M; Sanguinetti MC
    J Gen Physiol; 2010 Aug; 136(2):203-24. PubMed ID: 20660661
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The S4-S5 linker directly couples voltage sensor movement to the activation gate in the human ether-a'-go-go-related gene (hERG) K+ channel.
    Ferrer T; Rupp J; Piper DR; Tristani-Firouzi M
    J Biol Chem; 2006 May; 281(18):12858-64. PubMed ID: 16524878
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The hERG channel activator, RPR260243, enhances protective
    Shi YP; Pang Z; Venkateshappa R; Gunawan M; Kemp J; Truong E; Chang C; Lin E; Shafaattalab S; Faizi S; Rayani K; Tibbits GF; Claydon VE; Claydon TW
    Am J Physiol Heart Circ Physiol; 2020 Aug; 319(2):H251-H261. PubMed ID: 32559136
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Biophysical characterization of the new human ether-a-go-go-related gene channel opener NS3623 [N-(4-bromo-2-(1H-tetrazol-5-yl)-phenyl)-N'-(3'-trifluoromethylphenyl)urea].
    Hansen RS; Diness TG; Christ T; Wettwer E; Ravens U; Olesen SP; Grunnet M
    Mol Pharmacol; 2006 Oct; 70(4):1319-29. PubMed ID: 16825484
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The Link between Inactivation and High-Affinity Block of hERG1 Channels.
    Wu W; Gardner A; Sanguinetti MC
    Mol Pharmacol; 2015 Jun; 87(6):1042-50. PubMed ID: 25855787
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Ginsenoside Rg3, a Gating Modifier of EAG Family K+ Channels.
    Wu W; Gardner A; Sachse FB; Sanguinetti MC
    Mol Pharmacol; 2016 Oct; 90(4):469-82. PubMed ID: 27502018
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regulation of deactivation by an amino terminal domain in human ether-à-go-go-related gene potassium channels.
    Wang J; Trudeau MC; Zappia AM; Robertson GA
    J Gen Physiol; 1998 Nov; 112(5):637-47. PubMed ID: 9806971
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel potent human ether-a-go-go-related gene (hERG) potassium channel enhancers and their in vitro antiarrhythmic activity.
    Zhou J; Augelli-Szafran CE; Bradley JA; Chen X; Koci BJ; Volberg WA; Sun Z; Cordes JS
    Mol Pharmacol; 2005 Sep; 68(3):876-84. PubMed ID: 15976038
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular mapping of a site for Cd2+-induced modification of human ether-à-go-go-related gene (hERG) channel activation.
    Fernandez D; Ghanta A; Kinard KI; Sanguinetti MC
    J Physiol; 2005 Sep; 567(Pt 3):737-55. PubMed ID: 15975984
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The S4-S5 linker couples voltage sensing and activation of pacemaker channels.
    Chen J; Mitcheson JS; Tristani-Firouzi M; Lin M; Sanguinetti MC
    Proc Natl Acad Sci U S A; 2001 Sep; 98(20):11277-82. PubMed ID: 11553787
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular determinants for activation of human ether-à-go-go-related gene 1 potassium channels by 3-nitro-n-(4-phenoxyphenyl) benzamide.
    Garg V; Stary-Weinzinger A; Sachse F; Sanguinetti MC
    Mol Pharmacol; 2011 Oct; 80(4):630-7. PubMed ID: 21743002
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.