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3. Constitutional translocation breakpoint mapping by genome-wide paired-end sequencing identifies HACE1 as a putative Wilms tumour susceptibility gene. Slade I; Stephens P; Douglas J; Barker K; Stebbings L; Abbaszadeh F; Pritchard-Jones K; ; Cole R; Pizer B; Stiller C; Vujanic G; Scott RH; Stratton MR; Rahman N J Med Genet; 2010 May; 47(5):342-7. PubMed ID: 19948536 [TBL] [Abstract][Full Text] [Related]
4. HACE1 is a tumor suppressor gene candidate in natural killer cell neoplasms. Küçük C; Hu X; Iqbal J; Gaulard P; Klinkebiel D; Cornish A; Dave BJ; Chan WC Am J Pathol; 2013 Jan; 182(1):49-55. PubMed ID: 23142381 [TBL] [Abstract][Full Text] [Related]
5. HACE1 is a putative tumor suppressor gene in B-cell lymphomagenesis and is down-regulated by both deletion and epigenetic alterations. Bouzelfen A; Alcantara M; Kora H; Picquenot JM; Bertrand P; Cornic M; Mareschal S; Bohers E; Maingonnat C; Ruminy P; Adriouch S; Boyer O; Dubois S; Bastard C; Tilly H; Latouche JB; Jardin F Leuk Res; 2016 Jun; 45():90-100. PubMed ID: 27107267 [TBL] [Abstract][Full Text] [Related]
6. Loss of the Tumor Suppressor HACE1 Contributes to Cancer Progression. Li JC; Chang X; Chen Y; Li XZ; Zhang XL; Yang SM; Hu CJ; Zhang H Curr Drug Targets; 2019; 20(10):1018-1028. PubMed ID: 30827236 [TBL] [Abstract][Full Text] [Related]
7. HACE1 is a potential tumor suppressor in osteosarcoma. El-Naggar AM; Clarkson PW; Negri GL; Turgu B; Zhang F; Anglesio MS; Sorensen PH Cell Death Dis; 2019 Jan; 10(1):21. PubMed ID: 30622235 [TBL] [Abstract][Full Text] [Related]
8. HACE1, a potential tumor suppressor gene on 6q21, is not involved in extranodal natural killer/T-cell lymphoma pathophysiology. Sako N; Dessirier V; Bagot M; Bensussan A; Schmitt C Am J Pathol; 2014 Nov; 184(11):2899-907. PubMed ID: 25203537 [TBL] [Abstract][Full Text] [Related]
9. HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner. Turgu B; Zhang F; El-Naggar A; Negri GL; Kogler M; Tortola L; Johnson F; Ng T; Li A; Yapp D; Lockwood W; Martinez D; Maris JM; Daugaard M; Penninger JM; Hughes CS; Sorensen PH Oncogene; 2021 Mar; 40(11):1988-2001. PubMed ID: 33603169 [TBL] [Abstract][Full Text] [Related]
10. Aberrant methylation of the HACE1 gene is frequently detected in advanced colorectal cancer. Hibi K; Sakata M; Sakuraba K; Shirahata A; Goto T; Mizukami H; Saito M; Ishibashi K; Kigawa G; Nemoto H; Sanada Y Anticancer Res; 2008; 28(3A):1581-4. PubMed ID: 18630515 [TBL] [Abstract][Full Text] [Related]
11. Loss of the E3 ubiquitin ligase HACE1 results in enhanced Rac1 signaling contributing to breast cancer progression. Goka ET; Lippman ME Oncogene; 2015 Oct; 34(42):5395-405. PubMed ID: 25659579 [TBL] [Abstract][Full Text] [Related]
12. The HACE1 E3 ligase mediates RAC1-dependent control of mTOR signaling complexes. Turgu B; El-Naggar A; Kogler M; Tortola L; Zhang HF; Hassan M; Lizardo MM; Kung SH; Lam W; Penninger JM; Sorensen PH EMBO Rep; 2023 Dec; 24(12):e56815. PubMed ID: 37846480 [TBL] [Abstract][Full Text] [Related]
13. Uncovering and deciphering the pro-invasive role of HACE1 in melanoma cells. El-Hachem N; Habel N; Naiken T; Bzioueche H; Cheli Y; Beranger GE; Jaune E; Rouaud F; Nottet N; Reinier F; Gaudel C; Colosetti P; Bertolotto C; Ballotti R Cell Death Differ; 2018 Nov; 25(11):2010-2022. PubMed ID: 29515254 [TBL] [Abstract][Full Text] [Related]
14. HACE1 Prevents Lung Carcinogenesis via Inhibition of RAC-Family GTPases. Kogler M; Tortola L; Negri GL; Leopoldi A; El-Naggar AM; Mereiter S; Gomez-Diaz C; Nitsch R; Tortora D; Kavirayani AM; Gapp BV; Rao S; Uribesalgo I; Hoffmann D; Cikes D; Novatchkova M; Williams DA; Trent JM; Ikeda F; Daugaard M; Hagelkruys A; Sorensen PH; Penninger JM Cancer Res; 2020 Jul; 80(14):3009-3022. PubMed ID: 32366477 [TBL] [Abstract][Full Text] [Related]
15. The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate. Tortola L; Nitsch R; Bertrand MJM; Kogler M; Redouane Y; Kozieradzki I; Uribesalgo I; Fennell LM; Daugaard M; Klug H; Wirnsberger G; Wimmer R; Perlot T; Sarao R; Rao S; Hanada T; Takahashi N; Kernbauer E; Demiröz D; Lang M; Superti-Furga G; Decker T; Pichler A; Ikeda F; Kroemer G; Vandenabeele P; Sorensen PH; Penninger JM Cell Rep; 2016 May; 15(7):1481-1492. PubMed ID: 27160902 [TBL] [Abstract][Full Text] [Related]
16. Loss of the tumor suppressor Hace1 leads to ROS-dependent glutamine addiction. Cetinbas N; Daugaard M; Mullen AR; Hajee S; Rotblat B; Lopez A; Li A; DeBerardinis RJ; Sorensen PH Oncogene; 2015 Jul; 34(30):4005-10. PubMed ID: 25284589 [TBL] [Abstract][Full Text] [Related]
17. Association Between HACE1 Gene Polymorphisms and Wilms' Tumor Risk in a Chinese Population. Jia W; Deng Z; Zhu J; Fu W; Zhu S; Zhang LY; Hu J; Wang F; Xia H; Liu GC; He J Cancer Invest; 2017 Nov; 35(10):633-638. PubMed ID: 29243987 [TBL] [Abstract][Full Text] [Related]
18. HACE1-dependent protein degradation provides cardiac protection in response to haemodynamic stress. Zhang L; Chen X; Sharma P; Moon M; Sheftel AD; Dawood F; Nghiem MP; Wu J; Li RK; Gramolini AO; Sorensen PH; Penninger JM; Brumell JH; Liu PP Nat Commun; 2014 Mar; 5():3430. PubMed ID: 24614889 [TBL] [Abstract][Full Text] [Related]
19. HACE1, an E3 Ubiquitin Protein Ligase, Mitigates Kaposi's Sarcoma-Associated Herpesvirus Infection-Induced Oxidative Stress by Promoting Nrf2 Activity. Kumar B; Roy A; Asha K; Sharma-Walia N; Ansari MA; Chandran B J Virol; 2019 May; 93(9):. PubMed ID: 30787155 [TBL] [Abstract][Full Text] [Related]
20. UBE2QL1 is disrupted by a constitutional translocation associated with renal tumor predisposition and is a novel candidate renal tumor suppressor gene. Wake NC; Ricketts CJ; Morris MR; Prigmore E; Gribble SM; Skytte AB; Brown M; Clarke N; Banks RE; Hodgson S; Turnell AS; Maher ER; Woodward ER Hum Mutat; 2013 Dec; 34(12):1650-61. PubMed ID: 24000165 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]