163 related articles for article (PubMed ID: 17696253)
1. Lithocholic acid induction of the FGF19 promoter in intestinal cells is mediated by PXR.
Wistuba W; Gnewuch C; Liebisch G; Schmitz G; Langmann T
World J Gastroenterol; 2007 Aug; 13(31):4230-5. PubMed ID: 17696253
[TBL] [Abstract][Full Text] [Related]
2. Involvement of multiple elements in FXR-mediated transcriptional activation of FGF19.
Miyata M; Hata T; Yamakawa H; Kagawa T; Yoshinari K; Yamazoe Y
J Steroid Biochem Mol Biol; 2012 Oct; 132(1-2):41-7. PubMed ID: 22561792
[TBL] [Abstract][Full Text] [Related]
3. Pregnane X receptor mediated-transcription regulation of CYP3A by glycyrrhizin: a possible mechanism for its hepatoprotective property against lithocholic acid-induced injury.
Wang YG; Zhou JM; Ma ZC; Li H; Liang QD; Tan HL; Xiao CR; Zhang BL; Gao Y
Chem Biol Interact; 2012 Oct; 200(1):11-20. PubMed ID: 22982774
[TBL] [Abstract][Full Text] [Related]
4. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
Cerveny L; Svecova L; Anzenbacherova E; Vrzal R; Staud F; Dvorak Z; Ulrichova J; Anzenbacher P; Pavek P
Drug Metab Dispos; 2007 Jul; 35(7):1032-41. PubMed ID: 17392393
[TBL] [Abstract][Full Text] [Related]
5. Intestinal detoxification limits the activation of hepatic pregnane X receptor by lithocholic acid.
Owen BM; Milona A; van Mil S; Clements P; Holder J; Boudjelal M; Cairns W; Parker M; White R; Williamson C
Drug Metab Dispos; 2010 Jan; 38(1):143-9. PubMed ID: 19797606
[TBL] [Abstract][Full Text] [Related]
6. PXR induces CYP27A1 and regulates cholesterol metabolism in the intestine.
Li T; Chen W; Chiang JY
J Lipid Res; 2007 Feb; 48(2):373-84. PubMed ID: 17088262
[TBL] [Abstract][Full Text] [Related]
7. Rifampicin induction of CYP3A4 requires pregnane X receptor cross talk with hepatocyte nuclear factor 4alpha and coactivators, and suppression of small heterodimer partner gene expression.
Li T; Chiang JY
Drug Metab Dispos; 2006 May; 34(5):756-64. PubMed ID: 16455805
[TBL] [Abstract][Full Text] [Related]
8. Azole antimycotics differentially affect rifampicin-induced pregnane X receptor-mediated CYP3A4 gene expression.
Svecova L; Vrzal R; Burysek L; Anzenbacherova E; Cerveny L; Grim J; Trejtnar F; Kunes J; Pour M; Staud F; Anzenbacher P; Dvorak Z; Pavek P
Drug Metab Dispos; 2008 Feb; 36(2):339-48. PubMed ID: 17998298
[TBL] [Abstract][Full Text] [Related]
9. Pregnane X receptor activation induces FGF19-dependent tumor aggressiveness in humans and mice.
Wang H; Venkatesh M; Li H; Goetz R; Mukherjee S; Biswas A; Zhu L; Kaubisch A; Wang L; Pullman J; Whitney K; Kuro-o M; Roig AI; Shay JW; Mohammadi M; Mani S
J Clin Invest; 2011 Aug; 121(8):3220-32. PubMed ID: 21747170
[TBL] [Abstract][Full Text] [Related]
10. Mechanism of rifampicin and pregnane X receptor inhibition of human cholesterol 7 alpha-hydroxylase gene transcription.
Li T; Chiang JY
Am J Physiol Gastrointest Liver Physiol; 2005 Jan; 288(1):G74-84. PubMed ID: 15331348
[TBL] [Abstract][Full Text] [Related]
11. Involvement of Vitamin D receptor in the intestinal induction of human ABCB1.
Tachibana S; Yoshinari K; Chikada T; Toriyabe T; Nagata K; Yamazoe Y
Drug Metab Dispos; 2009 Aug; 37(8):1604-10. PubMed ID: 19460946
[TBL] [Abstract][Full Text] [Related]
12. Identification of pregnane X receptor binding sites in the regulatory regions of genes involved in bile acid homeostasis.
Frank C; Makkonen H; Dunlop TW; Matilainen M; Väisänen S; Carlberg C
J Mol Biol; 2005 Feb; 346(2):505-19. PubMed ID: 15670600
[TBL] [Abstract][Full Text] [Related]
13. SREBP-2 negatively regulates FXR-dependent transcription of FGF19 in human intestinal cells.
Miyata M; Hata T; Yamazoe Y; Yoshinari K
Biochem Biophys Res Commun; 2014 Jan; 443(2):477-82. PubMed ID: 24321096
[TBL] [Abstract][Full Text] [Related]
14. Acetylated deoxycholic (DCA) and cholic (CA) acids are potent ligands of pregnane X (PXR) receptor.
Carazo A; Hyrsova L; Dusek J; Chodounska H; Horvatova A; Berka K; Bazgier V; Gan-Schreier H; Chamulitrat W; Kudova E; Pavek P
Toxicol Lett; 2017 Jan; 265():86-96. PubMed ID: 27871908
[TBL] [Abstract][Full Text] [Related]
15. Investigation of Orlistat effects on PXR activation and CYP3A4 expression in primary human hepatocytes and human intestinal LS174T cells.
Novotna A; Doricakova A; Vrzal R; Maurel P; Pavek P; Dvorak Z
Eur J Pharm Sci; 2010 Oct; 41(2):276-80. PubMed ID: 20599501
[TBL] [Abstract][Full Text] [Related]
16. Modulation of pregnane X receptor (PXR) and constitutive androstane receptor (CAR) activation by ursolic acid (UA) attenuates rifampin-isoniazid cytotoxicity.
Chang HY; Chen CJ; Ma WC; Cheng WK; Lin YN; Lee YR; Chen JJ; Lim YP
Phytomedicine; 2017 Dec; 36():37-49. PubMed ID: 29157826
[TBL] [Abstract][Full Text] [Related]
17. Positive and negative regulation of human hepatic hydroxysteroid sulfotransferase (SULT2A1) gene transcription by rifampicin: roles of hepatocyte nuclear factor 4alpha and pregnane X receptor.
Fang HL; Strom SC; Ellis E; Duanmu Z; Fu J; Duniec-Dmuchowski Z; Falany CN; Falany JL; Kocarek TA; Runge-Morris M
J Pharmacol Exp Ther; 2007 Nov; 323(2):586-98. PubMed ID: 17687072
[TBL] [Abstract][Full Text] [Related]
18. Polycyclic aromatic hydrocarbons stimulate human CYP3A4 promoter activity via PXR.
Luckert C; Ehlers A; Buhrke T; Seidel A; Lampen A; Hessel S
Toxicol Lett; 2013 Oct; 222(2):180-8. PubMed ID: 23845848
[TBL] [Abstract][Full Text] [Related]
19. The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity.
Staudinger JL; Goodwin B; Jones SA; Hawkins-Brown D; MacKenzie KI; LaTour A; Liu Y; Klaassen CD; Brown KK; Reinhard J; Willson TM; Koller BH; Kliewer SA
Proc Natl Acad Sci U S A; 2001 Mar; 98(6):3369-74. PubMed ID: 11248085
[TBL] [Abstract][Full Text] [Related]
20. Pregnane X Receptor (PXR) expression in colorectal cancer cells restricts irinotecan chemosensitivity through enhanced SN-38 glucuronidation.
Raynal C; Pascussi JM; Leguelinel G; Breuker C; Kantar J; Lallemant B; Poujol S; Bonnans C; Joubert D; Hollande F; Lumbroso S; Brouillet JP; Evrard A
Mol Cancer; 2010 Mar; 9():46. PubMed ID: 20196838
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]