These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

157 related articles for article (PubMed ID: 17696334)

  • 1. CYP2C9 structure-metabolism relationships: optimizing the metabolic stability of COX-2 inhibitors.
    Ahlström MM; Ridderström M; Zamora I; Luthman K
    J Med Chem; 2007 Sep; 50(18):4444-52. PubMed ID: 17696334
    [TBL] [Abstract][Full Text] [Related]  

  • 2. CYP2C9 structure-metabolism relationships: substrates, inhibitors, and metabolites.
    Ahlström MM; Ridderström M; Zamora I
    J Med Chem; 2007 Nov; 50(22):5382-91. PubMed ID: 17915853
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Utility of MetaSite in improving metabolic stability of the neutral indomethacin amide derivative and selective cyclooxygenase-2 inhibitor 2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)-N-phenethyl-acetamide.
    Boyer D; Bauman JN; Walker DP; Kapinos B; Karki K; Kalgutkar AS
    Drug Metab Dispos; 2009 May; 37(5):999-1008. PubMed ID: 19196840
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design and synthesis of new water-soluble tetrazolide derivatives of celecoxib and rofecoxib as selective cyclooxygenase-2 (COX-2) inhibitors.
    Navidpour L; Amini M; Shafaroodi H; Abdi K; Ghahremani MH; Dehpour AR; Shafiee A
    Bioorg Med Chem Lett; 2006 Sep; 16(17):4483-7. PubMed ID: 16806914
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis, and biological evaluation of 1-(4-sulfamylphenyl)-3-trifluoromethyl-5-indolyl pyrazolines as cyclooxygenase-2 (COX-2) and lipoxygenase (LOX) inhibitors.
    Reddy MV; Billa VK; Pallela VR; Mallireddigari MR; Boominathan R; Gabriel JL; Reddy EP
    Bioorg Med Chem; 2008 Apr; 16(7):3907-16. PubMed ID: 18272371
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Selective COX-2 inhibitors. Part 1: synthesis and biological evaluation of phenylazobenzenesulfonamides.
    Tsai WJ; Shiao YJ; Lin SJ; Chiou WF; Lin LC; Yang TH; Teng CM; Wu TS; Yang LM
    Bioorg Med Chem Lett; 2006 Sep; 16(17):4440-3. PubMed ID: 16814546
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Selective COX-2 inhibitors. Part 2: synthesis and biological evaluation of 4-benzylideneamino- and 4-phenyliminomethyl-benzenesulfonamides.
    Lin SJ; Tsai WJ; Chiou WF; Yang TH; Yang LM
    Bioorg Med Chem; 2008 Mar; 16(5):2697-706. PubMed ID: 18063374
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, synthesis and pharmacological evaluation of 4-[2-alkylthio-5(4)-(4-substitutedphenyl)imidazole-4(5)yl]benzenesulfonamides as selective COX-2 inhibitors.
    Salimi M; Ghahremani MH; Naderi N; Amini M; Salimi E; Amanlou M; Abdi K; Salehi R; Shafiee A
    Acta Pharmacol Sin; 2007 Aug; 28(8):1254-60. PubMed ID: 17640491
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and biological evaluation of N-substituted-3,5-diphenyl-2-pyrazoline derivatives as cyclooxygenase (COX-2) inhibitors.
    Fioravanti R; Bolasco A; Manna F; Rossi F; Orallo F; Ortuso F; Alcaro S; Cirilli R
    Eur J Med Chem; 2010 Dec; 45(12):6135-8. PubMed ID: 20974503
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis of novel celecoxib analogues by bioisosteric replacement of sulfonamide as potent anti-inflammatory agents and cyclooxygenase inhibitors.
    Chandna N; Kumar S; Kaushik P; Kaushik D; Roy SK; Gupta GK; Jachak SM; Kapoor JK; Sharma PK
    Bioorg Med Chem; 2013 Aug; 21(15):4581-90. PubMed ID: 23769654
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis of celecoxib analogs that possess a N-hydroxypyrid-2(1H)one 5-lipoxygenase pharmacophore: biological evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.
    Chowdhury MA; Abdellatif KR; Dong Y; Das D; Suresh MR; Knaus EE
    Bioorg Med Chem Lett; 2008 Dec; 18(23):6138-41. PubMed ID: 18945614
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and biological evaluation of novel pyrazole compounds.
    Youssef AM; Neeland EG; Villanueva EB; White MS; El-Ashmawy IM; Patrick B; Klegeris A; Abd-El-Aziz AS
    Bioorg Med Chem; 2010 Aug; 18(15):5685-96. PubMed ID: 20609589
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pyridine analogues of nimesulide: design, synthesis, and in vitro and in vivo pharmacological evaluation as promising cyclooxygenase 1 and 2 inhibitors.
    Renard JF; Arslan D; Garbacki N; Pirotte B; de Leval X
    J Med Chem; 2009 Oct; 52(19):5864-71. PubMed ID: 19791801
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Crystal structure of human cytochrome P450 2C9 with bound warfarin.
    Williams PA; Cosme J; Ward A; Angove HC; Matak Vinković D; Jhoti H
    Nature; 2003 Jul; 424(6947):464-8. PubMed ID: 12861225
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Celecoxib analogs possessing a N-(4-nitrooxybutyl)piperidin-4-yl or N-(4-nitrooxybutyl)-1,2,3,6-tetrahydropyridin-4-yl nitric oxide donor moiety: synthesis, biological evaluation and nitric oxide release studies.
    Chowdhury MA; Abdellatif KR; Dong Y; Yu G; Huang Z; Rahman M; Das D; Velázquez CA; Suresh MR; Knaus EE
    Bioorg Med Chem Lett; 2010 Feb; 20(4):1324-9. PubMed ID: 20097072
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis, biological evaluation, and enzyme docking simulations of 1,5-diarylpyrrole-3-alkoxyethyl ethers as selective cyclooxygenase-2 inhibitors endowed with anti-inflammatory and antinociceptive activity.
    Anzini M; Rovini M; Cappelli A; Vomero S; Manetti F; Botta M; Sautebin L; Rossi A; Pergola C; Ghelardini C; Norcini M; Giordani A; Makovec F; Anzellotti P; Patrignani P; Biava M
    J Med Chem; 2008 Aug; 51(15):4476-81. PubMed ID: 18598017
    [TBL] [Abstract][Full Text] [Related]  

  • 17. NO-donor COX-2 inhibitors. New nitrooxy-substituted 1,5-diarylimidazoles endowed with COX-2 inhibitory and vasodilator properties.
    Chegaev K; Lazzarato L; Tosco P; Cena C; Marini E; Rolando B; Carrupt PA; Fruttero R; Gasco A
    J Med Chem; 2007 Apr; 50(7):1449-57. PubMed ID: 17335184
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Celecoxib analogs bearing benzofuran moiety as cyclooxygenase-2 inhibitors: design, synthesis and evaluation as potential anti-inflammatory agents.
    Hassan GS; Abou-Seri SM; Kamel G; Ali MM
    Eur J Med Chem; 2014 Apr; 76():482-93. PubMed ID: 24607877
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Conformer- and alignment-independent model for predicting structurally diverse competitive CYP2C9 inhibitors.
    Afzelius L; Zamora I; Masimirembwa CM; Karlén A; Andersson TB; Mecucci S; Baroni M; Cruciani G
    J Med Chem; 2004 Feb; 47(4):907-14. PubMed ID: 14761192
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 5-Heteroatom substituted pyrazoles as canine COX-2 inhibitors. Part III: molecular modeling studies on binding contribution of 1-(5-methylsulfonyl)pyrid-2-yl and 4-nitrile.
    Sakya SM; Hou X; Minich ML; Rast B; Shavnya A; DeMello KM; Cheng H; Li J; Jaynes BH; Mann DW; Petras CF; Seibel SB; Haven ML
    Bioorg Med Chem Lett; 2007 Feb; 17(4):1067-72. PubMed ID: 17126015
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.