BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

188 related articles for article (PubMed ID: 17698234)

  • 1. Circumventing the heterogeneity and instability of human serum albumin-interferon-alpha2b fusion protein by altering its orientation.
    Zhao HL; Xue C; Wang Y; Li XY; Xiong XH; Yao XQ; Liu ZM
    J Biotechnol; 2007 Sep; 131(3):245-52. PubMed ID: 17698234
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Increasing the homogeneity, stability and activity of human serum albumin and interferon-alpha2b fusion protein by linker engineering.
    Zhao HL; Yao XQ; Xue C; Wang Y; Xiong XH; Liu ZM
    Protein Expr Purif; 2008 Sep; 61(1):73-7. PubMed ID: 18541441
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Disruption of Pichia pastoris PMR1 gene decreases its folding capacity on human serum albumin and interferon-alpha2b fusion protein.
    Zhao HL; Xue C; Wang Y; Duan QF; Xiong XH; Yao XQ; Liu ZM
    Yeast; 2008 Apr; 25(4):279-86. PubMed ID: 18350526
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Elimination of the free sulfhydryl group in the human serum albumin (HSA) moiety of human interferon-alpha2b and HSA fusion protein increases its stability against mechanical and thermal stresses.
    Zhao HL; Xue C; Wang Y; Sun B; Yao XQ; Liu ZM
    Eur J Pharm Biopharm; 2009 Jun; 72(2):405-11. PubMed ID: 19462475
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Preparation and biological evaluation of a glycosylated fusion interferon directed to hepatic receptors.
    Cai G; Jiang M; Zhang B; Zhou Y; Zhang L; Lei J; Gu X; Cao G; Jin J; Zhang R
    Biol Pharm Bull; 2009 Mar; 32(3):440-3. PubMed ID: 19252292
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Balancing the pharmacokinetics and pharmacodynamics of interferon-α2b and human serum albumin fusion protein by proteolytic or reductive cleavage increases its in vivo therapeutic efficacy.
    Zhao HL; Xue C; Du JL; Ren M; Xia S; Liu ZM
    Mol Pharm; 2012 Mar; 9(3):664-70. PubMed ID: 22224503
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Construction and characterization of a potent, long-lasting recombinant human serum albumin-interferon α1 fusion protein expressed in Pichia pastoris.
    Tian S; Li Q; Yao W; Xu C
    Protein Expr Purif; 2013 Aug; 90(2):124-8. PubMed ID: 23748141
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Drug evaluation: Albuferon-alpha--an antiviral interferon-alpha/albumin fusion protein.
    Chemmanur AT; Wu GY
    Curr Opin Investig Drugs; 2006 Aug; 7(8):750-8. PubMed ID: 16955687
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Preparation and characterization of a potent, long-lasting recombinant human serum albumin-interferon-alpha2b fusion protein expressed in Pichia pastoris.
    Huang YS; Chen Z; Yang ZY; Wang TY; Zhou L; Wu JB; Zhou LF
    Eur J Pharm Biopharm; 2007 Sep; 67(2):301-8. PubMed ID: 17418549
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Development and biological activity of long-acting recombinant human interferon-α2b.
    Zhang Q; Wang C; Ma F; Yao L; Gao H; Zhu L; Zheng L
    BMC Biotechnol; 2020 Mar; 20(1):16. PubMed ID: 32169063
    [TBL] [Abstract][Full Text] [Related]  

  • 11. An IFN-beta-albumin fusion protein that displays improved pharmacokinetic and pharmacodynamic properties in nonhuman primates.
    Sung C; Nardelli B; LaFleur DW; Blatter E; Corcoran M; Olsen HS; Birse CE; Pickeral OK; Zhang J; Shah D; Moody G; Gentz S; Beebe L; Moore PA
    J Interferon Cytokine Res; 2003 Jan; 23(1):25-36. PubMed ID: 12639296
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Anti-serum albumin domain antibodies in the development of highly potent, efficacious and long-acting interferon.
    Walker A; Dunlevy G; Rycroft D; Topley P; Holt LJ; Herbert T; Davies M; Cook F; Holmes S; Jespers L; Herring C
    Protein Eng Des Sel; 2010 Apr; 23(4):271-8. PubMed ID: 20093262
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Evaluation of a single amino acid substitution at position 79 of human IFN-α2b in interferon-receptor assembly and activity.
    Talebi S; Saeedinia A; Zeinoddini M; Ahmadpour F; Sadeghizadeh M
    Prep Biochem Biotechnol; 2019; 49(8):735-743. PubMed ID: 31135267
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PEGylated interferon-alpha2b: a branched 40K polyethylene glycol derivative.
    Ramon J; Saez V; Baez R; Aldana R; Hardy E
    Pharm Res; 2005 Aug; 22(8):1374-86. PubMed ID: 16078148
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A new method to produce monoPEGylated dimeric cytokines shown with human interferon-α2b.
    Chang CH; Rossi EA; Cardillo TM; Nordstrom DL; McBride WJ; Goldenberg DM
    Bioconjug Chem; 2009 Oct; 20(10):1899-907. PubMed ID: 19736932
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Expression in Pichia pastoris and properties of human serum albumin-interferon alpha2b chimera].
    Chang SH; Gong X; Yang ZY; Wang TY; Ma GC; Ma QJ; Wu J
    Sheng Wu Gong Cheng Xue Bao; 2006 Mar; 22(2):173-9. PubMed ID: 16607939
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Long-term stabilization of a new freeze-dried and albumin-free formulation of recombinant human interferon alpha 2b.
    Ruiz L; Reyes N; Sotolongo J; Aroche K; Aldana R; Báez R; Hardy E
    PDA J Pharm Sci Technol; 2006; 60(1):72-8. PubMed ID: 17089680
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural and biologic characterization of pegylated recombinant IFN-alpha2b.
    Grace M; Youngster S; Gitlin G; Sydor W; Xie L; Westreich L; Jacobs S; Brassard D; Bausch J; Bordens R
    J Interferon Cytokine Res; 2001 Dec; 21(12):1103-15. PubMed ID: 11798469
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Production of potent long-lasting consensus interferon using albumin fusion technology in Pichia pastoris expression system.
    Naseem MU; Ahmed N; Khan MA; Tahir S; Zafar AU
    Protein Expr Purif; 2020 Feb; 166():105509. PubMed ID: 31604114
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pegylation of IFN-alpha and antiviral activity.
    Boulestin A; Kamar N; Sandres-Sauné K; Alric L; Vinel JP; Rostaing L; Izopet J
    J Interferon Cytokine Res; 2006 Dec; 26(12):849-53. PubMed ID: 17238827
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.