BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

143 related articles for article (PubMed ID: 17698635)

  • 1. NOTCH1 pathway activation is an early hallmark of SCL T leukemogenesis.
    Göthert JR; Brake RL; Smeets M; Dührsen U; Begley CG; Izon DJ
    Blood; 2007 Nov; 110(10):3753-62. PubMed ID: 17698635
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Modeling T-cell acute lymphoblastic leukemia induced by the SCL and LMO1 oncogenes.
    Tremblay M; Tremblay CS; Herblot S; Aplan PD; Hébert J; Perreault C; Hoang T
    Genes Dev; 2010 Jun; 24(11):1093-105. PubMed ID: 20516195
    [TBL] [Abstract][Full Text] [Related]  

  • 3. SCL, LMO1 and Notch1 reprogram thymocytes into self-renewing cells.
    Gerby B; Tremblay CS; Tremblay M; Rojas-Sutterlin S; Herblot S; Hébert J; Sauvageau G; Lemieux S; Lécuyer E; Veiga DF; Hoang T
    PLoS Genet; 2014 Dec; 10(12):e1004768. PubMed ID: 25522233
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Disordered T-cell development and T-cell malignancies in SCL LMO1 double-transgenic mice: parallels with E2A-deficient mice.
    Chervinsky DS; Zhao XF; Lam DH; Ellsworth M; Gross KW; Aplan PD
    Mol Cell Biol; 1999 Jul; 19(7):5025-35. PubMed ID: 10373552
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cre-loxP-mediated recombination between the SIL and SCL genes leads to a block in T-cell development at the CD4- CD8- to CD4+ CD8+ transition.
    Cheng Y; Zhang Z; Slape C; Aplan PD
    Neoplasia; 2007 Apr; 9(4):315-21. PubMed ID: 17460775
    [TBL] [Abstract][Full Text] [Related]  

  • 6. p16INK4A tumor suppressor gene expression and CD3epsilon deficiency but not pre-TCR deficiency inhibit TAL1-linked T-lineage leukemogenesis.
    Fasseu M; Aplan PD; Chopin M; Boissel N; Bories JC; Soulier J; von Boehmer H; Sigaux F; Regnault A
    Blood; 2007 Oct; 110(7):2610-9. PubMed ID: 17507663
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis.
    Bellavia D; Campese AF; Checquolo S; Balestri A; Biondi A; Cazzaniga G; Lendahl U; Fehling HJ; Hayday AC; Frati L; von Boehmer H; Gulino A; Screpanti I
    Proc Natl Acad Sci U S A; 2002 Mar; 99(6):3788-93. PubMed ID: 11891328
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Lunatic Fringe prolongs Delta/Notch-induced self-renewal of committed αβ T-cell progenitors.
    Yuan JS; Tan JB; Visan I; Matei IR; Urbanellis P; Xu K; Danska JS; Egan SE; Guidos CJ
    Blood; 2011 Jan; 117(4):1184-95. PubMed ID: 21097675
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Notch1 inhibition targets the leukemia-initiating cells in a Tal1/Lmo2 mouse model of T-ALL.
    Tatarek J; Cullion K; Ashworth T; Gerstein R; Aster JC; Kelliher MA
    Blood; 2011 Aug; 118(6):1579-90. PubMed ID: 21670468
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Monoallelic
    Veiga DFT; Tremblay M; Gerby B; Herblot S; Haman A; Gendron P; Lemieux S; Zúñiga-Pflücker JC; Hébert J; Cohen JP; Hoang T
    Front Immunol; 2022; 13():867443. PubMed ID: 35401501
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Stage-specific roles for Zmiz1 in Notch-dependent steps of early T-cell development.
    Wang Q; Yan R; Pinnell N; McCarter AC; Oh Y; Liu Y; Sha C; Garber NF; Chen Y; Wu Q; Ku CJ; Tran I; Serna Alarcon A; Kuick R; Engel JD; Maillard I; Cierpicki T; Chiang MY
    Blood; 2018 Sep; 132(12):1279-1292. PubMed ID: 30076146
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cross talk among Notch3, pre-TCR, and Tal1 in T-cell development and leukemogenesis.
    Talora C; Cialfi S; Oliviero C; Palermo R; Pascucci M; Frati L; Vacca A; Gulino A; Screpanti I
    Blood; 2006 Apr; 107(8):3313-20. PubMed ID: 16368887
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The DNA binding activity of TAL-1 is not required to induce leukemia/lymphoma in mice.
    O'Neil J; Billa M; Oikemus S; Kelliher M
    Oncogene; 2001 Jun; 20(29):3897-905. PubMed ID: 11439353
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Constitutive Notch signalling promotes CD4 CD8 thymocyte differentiation in the absence of the pre-TCR complex, by mimicking pre-TCR signals.
    Michie AM; Chan AC; Ciofani M; Carleton M; Lefebvre JM; He Y; Allman DM; Wiest DL; Zúñiga-Pflücker JC; Izon DJ
    Int Immunol; 2007 Dec; 19(12):1421-30. PubMed ID: 17981791
    [TBL] [Abstract][Full Text] [Related]  

  • 15. NF-kappaB activation in premalignant mouse tal-1/scl thymocytes and tumors.
    O'Neil J; Ventura JJ; Cusson N; Kelliher M
    Blood; 2003 Oct; 102(7):2593-6. PubMed ID: 12816868
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cooperation of Gata3, c-Myc and Notch in malignant transformation of double positive thymocytes.
    van Hamburg JP; de Bruijn MJ; Dingjan GM; Beverloo HB; Diepstraten H; Ling KW; Hendriks RW
    Mol Immunol; 2008 Jun; 45(11):3085-95. PubMed ID: 18471881
    [TBL] [Abstract][Full Text] [Related]  

  • 17. OLIG2 (BHLHB1), a bHLH transcription factor, contributes to leukemogenesis in concert with LMO1.
    Lin YW; Deveney R; Barbara M; Iscove NN; Nimer SD; Slape C; Aplan PD
    Cancer Res; 2005 Aug; 65(16):7151-8. PubMed ID: 16103065
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Notch1 mutations are important for leukemic transformation in murine models of precursor-T leukemia/lymphoma.
    Lin YW; Nichols RA; Letterio JJ; Aplan PD
    Blood; 2006 Mar; 107(6):2540-3. PubMed ID: 16282337
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Notch1 regulates maturation of CD4+ and CD8+ thymocytes by modulating TCR signal strength.
    Izon DJ; Punt JA; Xu L; Karnell FG; Allman D; Myung PS; Boerth NJ; Pui JC; Koretzky GA; Pear WS
    Immunity; 2001 Mar; 14(3):253-64. PubMed ID: 11290335
    [TBL] [Abstract][Full Text] [Related]  

  • 20. scid Thymocytes with TCRbeta gene rearrangements are targets for the oncogenic effect of SCL and LMO1 transgenes.
    Chervinsky DS; Lam DH; Melman MP; Gross KW; Aplan PD
    Cancer Res; 2001 Sep; 61(17):6382-7. PubMed ID: 11522630
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.