These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

501 related articles for article (PubMed ID: 17698840)

  • 1. Mcl-1 as a buffer for proapoptotic Bcl-2 family members during TRAIL-induced apoptosis: a mechanistic basis for sorafenib (Bay 43-9006)-induced TRAIL sensitization.
    Meng XW; Lee SH; Dai H; Loegering D; Yu C; Flatten K; Schneider P; Dai NT; Kumar SK; Smith BD; Karp JE; Adjei AA; Kaufmann SH
    J Biol Chem; 2007 Oct; 282(41):29831-46. PubMed ID: 17698840
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The multikinase inhibitor sorafenib potentiates TRAIL lethality in human leukemia cells in association with Mcl-1 and cFLIPL down-regulation.
    Rosato RR; Almenara JA; Coe S; Grant S
    Cancer Res; 2007 Oct; 67(19):9490-500. PubMed ID: 17909059
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sorafenib inhibits STAT3 activation to enhance TRAIL-mediated apoptosis in human pancreatic cancer cells.
    Huang S; Sinicrope FA
    Mol Cancer Ther; 2010 Mar; 9(3):742-50. PubMed ID: 20197401
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The proteasome inhibitor MG132 potentiates TRAIL receptor agonist-induced apoptosis by stabilizing tBid and Bik in human head and neck squamous cell carcinoma cells.
    Sung ES; Park KJ; Choi HJ; Kim CH; Kim YS
    Exp Cell Res; 2012 Aug; 318(13):1564-76. PubMed ID: 22513214
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Specific cleavage of Mcl-1 by caspase-3 in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in Jurkat leukemia T cells.
    Weng C; Li Y; Xu D; Shi Y; Tang H
    J Biol Chem; 2005 Mar; 280(11):10491-500. PubMed ID: 15637055
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Bim plays a crucial role in synergistic induction of apoptosis by the histone deacetylase inhibitor SBHA and TRAIL in melanoma cells.
    Gillespie S; Borrow J; Zhang XD; Hersey P
    Apoptosis; 2006 Dec; 11(12):2251-65. PubMed ID: 17051334
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tumor necrosis factor-related apoptosis-inducing ligand activates a lysosomal pathway of apoptosis that is regulated by Bcl-2 proteins.
    Werneburg NW; Guicciardi ME; Bronk SF; Kaufmann SH; Gores GJ
    J Biol Chem; 2007 Sep; 282(39):28960-28970. PubMed ID: 17686764
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent manner.
    Kazi A; Sun J; Doi K; Sung SS; Takahashi Y; Yin H; Rodriguez JM; Becerril J; Berndt N; Hamilton AD; Wang HG; Sebti SM
    J Biol Chem; 2011 Mar; 286(11):9382-92. PubMed ID: 21148306
    [TBL] [Abstract][Full Text] [Related]  

  • 9. BH3 mimetic ABT-737 potentiates TRAIL-mediated apoptotic signaling by unsequestering Bim and Bak in human pancreatic cancer cells.
    Huang S; Sinicrope FA
    Cancer Res; 2008 Apr; 68(8):2944-51. PubMed ID: 18413764
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dual inhibition of Bcl-2 and Bcl-xL strikingly enhances PI3K inhibition-induced apoptosis in human myeloid leukemia cells through a GSK3- and Bim-dependent mechanism.
    Rahmani M; Aust MM; Attkisson E; Williams DC; Ferreira-Gonzalez A; Grant S
    Cancer Res; 2013 Feb; 73(4):1340-51. PubMed ID: 23243017
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of Bcl-2 antiapoptotic members by obatoclax potently enhances sorafenib-induced apoptosis in human myeloid leukemia cells through a Bim-dependent process.
    Rahmani M; Aust MM; Attkisson E; Williams DC; Ferreira-Gonzalez A; Grant S
    Blood; 2012 Jun; 119(25):6089-98. PubMed ID: 22446485
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Apoptosis induced by the kinase inhibitor BAY 43-9006 in human leukemia cells involves down-regulation of Mcl-1 through inhibition of translation.
    Rahmani M; Davis EM; Bauer C; Dent P; Grant S
    J Biol Chem; 2005 Oct; 280(42):35217-27. PubMed ID: 16109713
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sorafenib inhibits ERK1/2 and MCL-1(L) phosphorylation levels resulting in caspase-independent cell death in malignant pleural mesothelioma.
    Katz SI; Zhou L; Chao G; Smith CD; Ferrara T; Wang W; Dicker DT; El-Deiry WS
    Cancer Biol Ther; 2009 Dec; 8(24):2406-16. PubMed ID: 20038816
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mcl-1 interacts with truncated Bid and inhibits its induction of cytochrome c release and its role in receptor-mediated apoptosis.
    Clohessy JG; Zhuang J; de Boer J; Gil-Gómez G; Brady HJ
    J Biol Chem; 2006 Mar; 281(9):5750-9. PubMed ID: 16380381
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The role of Mcl-1 downregulation in the proapoptotic activity of the multikinase inhibitor BAY 43-9006.
    Yu C; Bruzek LM; Meng XW; Gores GJ; Carter CA; Kaufmann SH; Adjei AA
    Oncogene; 2005 Oct; 24(46):6861-9. PubMed ID: 16007148
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interrelated roles for Mcl-1 and BIM in regulation of TRAIL-mediated mitochondrial apoptosis.
    Han J; Goldstein LA; Gastman BR; Rabinowich H
    J Biol Chem; 2006 Apr; 281(15):10153-63. PubMed ID: 16478725
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Reduction of TRAIL-induced Mcl-1 and cIAP2 by c-Myc or sorafenib sensitizes resistant human cancer cells to TRAIL-induced death.
    Ricci MS; Kim SH; Ogi K; Plastaras JP; Ling J; Wang W; Jin Z; Liu YY; Dicker DT; Chiao PJ; Flaherty KT; Smith CD; El-Deiry WS
    Cancer Cell; 2007 Jul; 12(1):66-80. PubMed ID: 17613437
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies.
    Kim H; Rafiuddin-Shah M; Tu HC; Jeffers JR; Zambetti GP; Hsieh JJ; Cheng EH
    Nat Cell Biol; 2006 Dec; 8(12):1348-58. PubMed ID: 17115033
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Endogenous Bak inhibitors Mcl-1 and Bcl-xL: differential impact on TRAIL resistance in Bax-deficient carcinoma.
    Gillissen B; Wendt J; Richter A; Richter A; Müer A; Overkamp T; Gebhardt N; Preissner R; Belka C; Dörken B; Daniel PT
    J Cell Biol; 2010 Mar; 188(6):851-62. PubMed ID: 20308427
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bax/Bak-independent mitochondrial depolarization and reactive oxygen species induction by sorafenib overcome resistance to apoptosis in renal cell carcinoma.
    Gillissen B; Richter A; Richter A; Preissner R; Schulze-Osthoff K; Essmann F; Daniel PT
    J Biol Chem; 2017 Apr; 292(16):6478-6492. PubMed ID: 28154184
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.