248 related articles for article (PubMed ID: 17699722)
1. CCG-1423: a small-molecule inhibitor of RhoA transcriptional signaling.
Evelyn CR; Wade SM; Wang Q; Wu M; Iñiguez-Lluhí JA; Merajver SD; Neubig RR
Mol Cancer Ther; 2007 Aug; 6(8):2249-60. PubMed ID: 17699722
[TBL] [Abstract][Full Text] [Related]
2. Pharmacological Inhibition of Myocardin-related Transcription Factor Pathway Blocks Lung Metastases of RhoC-Overexpressing Melanoma.
Haak AJ; Appleton KM; Lisabeth EM; Misek SA; Ji Y; Wade SM; Bell JL; Rockwell CE; Airik M; Krook MA; Larsen SD; Verhaegen M; Lawlor ER; Neubig RR
Mol Cancer Ther; 2017 Jan; 16(1):193-204. PubMed ID: 27837031
[TBL] [Abstract][Full Text] [Related]
3. Optimization of novel nipecotic bis(amide) inhibitors of the Rho/MKL1/SRF transcriptional pathway as potential anti-metastasis agents.
Bell JL; Haak AJ; Wade SM; Kirchhoff PD; Neubig RR; Larsen SD
Bioorg Med Chem Lett; 2013 Jul; 23(13):3826-32. PubMed ID: 23707258
[TBL] [Abstract][Full Text] [Related]
4. cGMP-dependent protein kinase inhibits serum-response element-dependent transcription by inhibiting rho activation and functions.
Gudi T; Chen JC; Casteel DE; Seasholtz TM; Boss GR; Pilz RB
J Biol Chem; 2002 Oct; 277(40):37382-93. PubMed ID: 12119292
[TBL] [Abstract][Full Text] [Related]
5. Novel Rho/MRTF/SRF inhibitors block matrix-stiffness and TGF-β-induced fibrogenesis in human colonic myofibroblasts.
Johnson LA; Rodansky ES; Haak AJ; Larsen SD; Neubig RR; Higgins PD
Inflamm Bowel Dis; 2014 Jan; 20(1):154-65. PubMed ID: 24280883
[TBL] [Abstract][Full Text] [Related]
6. Small-Molecule Inhibition of Rho/MKL/SRF Transcription in Prostate Cancer Cells: Modulation of Cell Cycle, ER Stress, and Metastasis Gene Networks.
Evelyn CR; Lisabeth EM; Wade SM; Haak AJ; Johnson CN; Lawlor ER; Neubig RR
Microarrays (Basel); 2016 May; 5(2):. PubMed ID: 27600078
[TBL] [Abstract][Full Text] [Related]
7. Design, synthesis and prostate cancer cell-based studies of analogs of the Rho/MKL1 transcriptional pathway inhibitor, CCG-1423.
Evelyn CR; Bell JL; Ryu JG; Wade SM; Kocab A; Harzdorf NL; Showalter HD; Neubig RR; Larsen SD
Bioorg Med Chem Lett; 2010 Jan; 20(2):665-72. PubMed ID: 19963382
[TBL] [Abstract][Full Text] [Related]
8. Megakaryoblastic leukemia 1, a potent transcriptional coactivator for serum response factor (SRF), is required for serum induction of SRF target genes.
Cen B; Selvaraj A; Burgess RC; Hitzler JK; Ma Z; Morris SW; Prywes R
Mol Cell Biol; 2003 Sep; 23(18):6597-608. PubMed ID: 12944485
[TBL] [Abstract][Full Text] [Related]
9. Pharmacological intervention of MKL/SRF signaling by CCG-1423 impedes endothelial cell migration and angiogenesis.
Gau D; Veon W; Capasso TL; Bottcher R; Shroff S; Roman BL; Roy P
Angiogenesis; 2017 Nov; 20(4):663-672. PubMed ID: 28638990
[TBL] [Abstract][Full Text] [Related]
10. Actin-mediated gene expression depends on RhoA and Rac1 signaling in proximal tubular epithelial cells.
Giehl K; Keller C; Muehlich S; Goppelt-Struebe M
PLoS One; 2015; 10(3):e0121589. PubMed ID: 25816094
[TBL] [Abstract][Full Text] [Related]
11. Rho signaling inhibitor, CCG-1423, inhibits axonal elongation and dendritic complexity of rat cortical neurons.
Kikuchi K; Shiota J; Yamada T; Ishikawa M; Ihara D; Fukuchi M; Tsuda M; Tabuchi A
Biochem Biophys Res Commun; 2017 Oct; 492(3):474-479. PubMed ID: 28830810
[TBL] [Abstract][Full Text] [Related]
12. RhoA and RhoC -siRNA inhibit the proliferation and invasiveness activity of human gastric carcinoma by Rho/PI3K/Akt pathway.
Sun HW; Tong SL; He J; Wang Q; Zou L; Ma SJ; Tan HY; Luo JF; Wu HX
World J Gastroenterol; 2007 Jul; 13(25):3517-22. PubMed ID: 17659701
[TBL] [Abstract][Full Text] [Related]
13. RhoA- and RhoD-dependent regulatory switch of Galpha subunit signaling by PAR-1 receptors in cellular invasion.
Nguyen QD; Faivre S; Bruyneel E; Rivat C; Seto M; Endo T; Mareel M; Emami S; Gespach C
FASEB J; 2002 Apr; 16(6):565-76. PubMed ID: 11919159
[TBL] [Abstract][Full Text] [Related]
14. Curcumin inhibits LPA-induced invasion by attenuating RhoA/ROCK/MMPs pathway in MCF7 breast cancer cells.
Sun K; Duan X; Cai H; Liu X; Yang Y; Li M; Zhang X; Wang J
Clin Exp Med; 2016 Feb; 16(1):37-47. PubMed ID: 25596714
[TBL] [Abstract][Full Text] [Related]
15. The RhoA/Rho kinase pathway regulates nuclear localization of serum response factor.
Liu HW; Halayko AJ; Fernandes DJ; Harmon GS; McCauley JA; Kocieniewski P; McConville J; Fu Y; Forsythe SM; Kogut P; Bellam S; Dowell M; Churchill J; Lesso H; Kassiri K; Mitchell RW; Hershenson MB; Camoretti-Mercado B; Solway J
Am J Respir Cell Mol Biol; 2003 Jul; 29(1):39-47. PubMed ID: 12600823
[TBL] [Abstract][Full Text] [Related]
16. Isoprenylation is necessary for the full invasive potential of RhoA overexpression in human melanoma cells.
Collisson EA; Carranza DC; Chen IY; Kolodney MS
J Invest Dermatol; 2002 Nov; 119(5):1172-6. PubMed ID: 12445208
[TBL] [Abstract][Full Text] [Related]
17. Stereospecific Inhibitory Effects of CCG-1423 on the Cellular Events Mediated by Myocardin-Related Transcription Factor A.
Watanabe B; Minami S; Ishida H; Yoshioka R; Nakagawa Y; Morita T; Hayashi K
PLoS One; 2015; 10(8):e0136242. PubMed ID: 26295164
[TBL] [Abstract][Full Text] [Related]
18. G Protein betagamma subunits stimulate p114RhoGEF, a guanine nucleotide exchange factor for RhoA and Rac1: regulation of cell shape and reactive oxygen species production.
Niu J; Profirovic J; Pan H; Vaiskunaite R; Voyno-Yasenetskaya T
Circ Res; 2003 Oct; 93(9):848-56. PubMed ID: 14512443
[TBL] [Abstract][Full Text] [Related]
19. Anti-RhoA and anti-RhoC siRNAs inhibit the proliferation and invasiveness of MDA-MB-231 breast cancer cells in vitro and in vivo.
Pillé JY; Denoyelle C; Varet J; Bertrand JR; Soria J; Opolon P; Lu H; Pritchard LL; Vannier JP; Malvy C; Soria C; Li H
Mol Ther; 2005 Feb; 11(2):267-74. PubMed ID: 15668138
[TBL] [Abstract][Full Text] [Related]
20. Formin-like2 regulates Rho/ROCK pathway to promote actin assembly and cell invasion of colorectal cancer.
Zeng Y; Xie H; Qiao Y; Wang J; Zhu X; He G; Li Y; Ren X; Wang F; Liang L; Ding Y
Cancer Sci; 2015 Oct; 106(10):1385-93. PubMed ID: 26258642
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
