BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

399 related articles for article (PubMed ID: 17700363)

  • 1. The L84F polymorphism in the O6-Methylguanine-DNA-Methyltransferase (MGMT) gene is associated with increased hypoxanthine phosphoribosyltransferase (HPRT) mutant frequency in lymphocytes of tobacco smokers.
    Hill CE; Wickliffe JK; Guerin AT; Kinslow CJ; Wolfe KJ; Ammenheuser MM; Abdel-Rahman SZ
    Pharmacogenet Genomics; 2007 Sep; 17(9):743-53. PubMed ID: 17700363
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The L84F and the I143V polymorphisms in the O6-methylguanine-DNA-methyltransferase (MGMT) gene increase human sensitivity to the genotoxic effects of the tobacco-specific nitrosamine carcinogen NNK.
    Hill CE; Wickliffe JK; Wolfe KJ; Kinslow CJ; Lopez MS; Abdel-Rahman SZ
    Pharmacogenet Genomics; 2005 Aug; 15(8):571-8. PubMed ID: 16007001
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Association of O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation with p53 mutation occurrence in non-small cell lung cancer with different histology, gender, and smoking status.
    Wu JY; Wang J; Lai JC; Cheng YW; Yeh KT; Wu TC; Chen CY; Lee H
    Ann Surg Oncol; 2008 Nov; 15(11):3272-7. PubMed ID: 18712569
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Genetic polymorphisms of methylenetetrahydrofolate reductase and promoter methylation of MGMT and FHIT genes in diffuse large B cell lymphoma risk in Middle East.
    Siraj AK; Ibrahim M; Al-Rasheed M; Bu R; Bavi P; Jehan Z; Abubaker J; Murad W; Al-Dayel F; Ezzat A; El-Solh H; Uddin S; Al-Kuraya K
    Ann Hematol; 2007 Dec; 86(12):887-95. PubMed ID: 17712558
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents.
    Kaina B; Christmann M; Naumann S; Roos WP
    DNA Repair (Amst); 2007 Aug; 6(8):1079-99. PubMed ID: 17485253
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Genetic variants in MGMT and risk of lung cancer in Southeastern Chinese: a haplotype-based analysis.
    Hu Z; Wang H; Shao M; Jin G; Sun W; Wang Y; Liu H; Wang Y; Ma H; Qian J; Jin L; Wei Q; Lu D; Huang W; Shen H
    Hum Mutat; 2007 May; 28(5):431-40. PubMed ID: 17285603
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Polymorphisms in MGMT and DNA repair genes and the risk of esophageal adenocarcinoma.
    Doecke J; Zhao ZZ; Pandeya N; Sadeghi S; Stark M; Green AC; Hayward NK; Webb PM; Whiteman DC;
    Int J Cancer; 2008 Jul; 123(1):174-80. PubMed ID: 18386788
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular modeling of O6-methylguanine-DNA methyltransferase mutant proteins encoded by single nucleotide polymorphisms.
    Schwarzl SM; Smith JC; Kaina B; Efferth T
    Int J Mol Med; 2005 Oct; 16(4):553-7. PubMed ID: 16142386
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Promoter methylation of O(6)-methylguanine-DNA-methyltransferase in lung cancer is regulated by p53.
    Lai JC; Cheng YW; Goan YG; Chang JT; Wu TC; Chen CY; Lee H
    DNA Repair (Amst); 2008 Aug; 7(8):1352-63. PubMed ID: 18555750
    [TBL] [Abstract][Full Text] [Related]  

  • 10. O(6)-methylguanine-DNA methyltransferase (MGMT): impact on cancer risk in response to tobacco smoke.
    Christmann M; Kaina B
    Mutat Res; 2012 Aug; 736(1-2):64-74. PubMed ID: 21708177
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Strand- and sequence-specific attenuation of N-methyl-N'-nitro-N-nitrosoguanidine-induced G.C to A.T transitions by expression of human 6-methylguanine-DNA methyltransferase in Chinese hamster ovary cells.
    Yang JL; Hsieh FP; Lee PC; Tseng HJ
    Cancer Res; 1994 Jul; 54(14):3857-63. PubMed ID: 8033107
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Studies on the HPRT mutant frequency in T lymphocytes from healthy Indian male population as a function of age and smoking.
    Kumar PR; Hamza VZ; Mohankumar MN; Jeevanram RK
    Mutat Res; 2004 Nov; 556(1-2):107-16. PubMed ID: 15491638
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular analysis of hprt gene mutations in skin fibroblasts of rats exposed in vivo to N-methyl-N-nitrosourea or N-ethyl-N-nitrosourea.
    Jansen JG; Mohn GR; Vrieling H; van Teijlingen CM; Lohman PH; van Zeeland AA
    Cancer Res; 1994 May; 54(9):2478-85. PubMed ID: 8162597
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Careful exclusion of non-neoplastic brain components is required for an appropriate evaluation of O6-methylguanine-DNA methyltransferase status in glioma: relationship between immunohistochemistry and methylation analysis.
    Sasai K; Nodagashira M; Nishihara H; Aoyanagi E; Wang L; Katoh M; Murata J; Ozaki Y; Ito T; Fujimoto S; Kaneko S; Nagashima K; Tanaka S
    Am J Surg Pathol; 2008 Aug; 32(8):1220-7. PubMed ID: 18580490
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Prognostic significance of molecular markers and extent of resection in primary glioblastoma patients.
    Felsberg J; Rapp M; Loeser S; Fimmers R; Stummer W; Goeppert M; Steiger HJ; Friedensdorf B; Reifenberger G; Sabel MC
    Clin Cancer Res; 2009 Nov; 15(21):6683-93. PubMed ID: 19861461
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Detection of MGMT promoter methylation in normal individuals is strongly associated with the T allele of the rs16906252 MGMT promoter single nucleotide polymorphism.
    Candiloro IL; Dobrovic A
    Cancer Prev Res (Phila); 2009 Oct; 2(10):862-7. PubMed ID: 19789298
    [TBL] [Abstract][Full Text] [Related]  

  • 17. No-observed effect levels are associated with up-regulation of MGMT following MMS exposure.
    Doak SH; Brüsehafer K; Dudley E; Quick E; Johnson G; Newton RP; Jenkins GJ
    Mutat Res; 2008 Dec; 648(1-2):9-14. PubMed ID: 18992265
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular analysis of hprt mutant lymphocytes from 1, 3-butadiene-exposed workers.
    Ma H; Wood TG; Ammenheuser MM; Rosenblatt JI; Ward JB
    Environ Mol Mutagen; 2000; 36(1):59-71. PubMed ID: 10918361
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel mechanism whereby nuclear factor kappaB mediates DNA damage repair through regulation of O(6)-methylguanine-DNA-methyltransferase.
    Lavon I; Fuchs D; Zrihan D; Efroni G; Zelikovitch B; Fellig Y; Siegal T
    Cancer Res; 2007 Sep; 67(18):8952-9. PubMed ID: 17875738
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular analysis of mutations at the HPRT and TK loci of human lymphoblastoid cells after combined treatments with 3'-azido-3'-deoxythymidine and 2',3'-dideoxyinosinedagger.
    Meng Q; Su T; O'Neill JP; Walker VE
    Environ Mol Mutagen; 2002; 39(4):282-95. PubMed ID: 12112380
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.