197 related articles for article (PubMed ID: 17702526)
1. Metabolism of benzo[a]pyrene in human bronchoalveolar H358 cells using liquid chromatography-mass spectrometry.
Jiang H; Gelhaus SL; Mangal D; Harvey RG; Blair IA; Penning TM
Chem Res Toxicol; 2007 Sep; 20(9):1331-41. PubMed ID: 17702526
[TBL] [Abstract][Full Text] [Related]
2. Competing roles of cytochrome P450 1A1/1B1 and aldo-keto reductase 1A1 in the metabolic activation of (+/-)-7,8-dihydroxy-7,8-dihydro-benzo[a]pyrene in human bronchoalveolar cell extracts.
Jiang H; Shen YM; Quinn AM; Penning TM
Chem Res Toxicol; 2005 Feb; 18(2):365-74. PubMed ID: 15720144
[TBL] [Abstract][Full Text] [Related]
3. Regulation of benzo[a]pyrene-mediated DNA- and glutathione-adduct formation by 2,3,7,8-tetrachlorodibenzo-p-dioxin in human lung cells.
Gelhaus SL; Harvey RG; Penning TM; Blair IA
Chem Res Toxicol; 2011 Jan; 24(1):89-98. PubMed ID: 21028851
[TBL] [Abstract][Full Text] [Related]
4. Quantitation of benzo[a]pyrene metabolic profiles in human bronchoalveolar (H358) cells by stable isotope dilution liquid chromatography-atmospheric pressure chemical ionization mass spectrometry.
Lu D; Harvey RG; Blair IA; Penning TM
Chem Res Toxicol; 2011 Nov; 24(11):1905-14. PubMed ID: 21962213
[TBL] [Abstract][Full Text] [Related]
5. Competing roles of aldo-keto reductase 1A1 and cytochrome P4501B1 in benzo[a]pyrene-7,8-diol activation in human bronchoalveolar H358 cells: role of AKRs in P4501B1 induction.
Jiang H; Vudathala DK; Blair IA; Penning TM
Chem Res Toxicol; 2006 Jan; 19(1):68-78. PubMed ID: 16411658
[TBL] [Abstract][Full Text] [Related]
6. Aldo-keto reductase- and cytochrome P450-dependent formation of benzo[a]pyrene-derived DNA adducts in human bronchoalveolar cells.
Ruan Q; Gelhaus SL; Penning TM; Harvey RG; Blair IA
Chem Res Toxicol; 2007 Mar; 20(3):424-31. PubMed ID: 17295519
[TBL] [Abstract][Full Text] [Related]
7. Comparisons of (+/-)-benzo[a]pyrene-trans-7,8-dihydrodiol activation by human cytochrome P450 and aldo-keto reductase enzymes: effect of redox state and expression levels.
Quinn AM; Penning TM
Chem Res Toxicol; 2008 May; 21(5):1086-94. PubMed ID: 18402469
[TBL] [Abstract][Full Text] [Related]
8. Aldo-keto reductases protect lung adenocarcinoma cells from the acute toxicity of B[a]P-7,8-trans-dihydrodiol.
Abedin Z; Sen S; Field J
Chem Res Toxicol; 2012 Jan; 25(1):113-21. PubMed ID: 22053912
[TBL] [Abstract][Full Text] [Related]
9. Inflammatory mediators accelerate metabolism of benzo[a]pyrene in rat alveolar type II cells: the role of enhanced cytochrome P450 1B1 expression.
Smerdová L; Neča J; Svobodová J; Topinka J; Schmuczerová J; Kozubík A; Machala M; Vondráček J
Toxicology; 2013 Dec; 314(1):30-8. PubMed ID: 24025706
[TBL] [Abstract][Full Text] [Related]
10. Importance of CYP1A1 and CYP1B1 in bioactivation of benzo[a]pyrene in human lung cell lines.
Uppstad H; Øvrebø S; Haugen A; Mollerup S
Toxicol Lett; 2010 Feb; 192(2):221-8. PubMed ID: 19879933
[TBL] [Abstract][Full Text] [Related]
11. Metabolism of benzo[a]pyrene and benzo[a]pyrene-7,8-diol by human cytochrome P450 1B1.
Kim JH; Stansbury KH; Walker NJ; Trush MA; Strickland PT; Sutter TR
Carcinogenesis; 1998 Oct; 19(10):1847-53. PubMed ID: 9806168
[TBL] [Abstract][Full Text] [Related]
12. Role of cytochrome P450 enzyme induction in the metabolic activation of benzo[c]phenanthrene in human cell lines and mouse epidermis.
Einolf HJ; Story WT; Marcus CB; Larsen MC; Jefcoate CR; Greenlee WF; Yagi H; Jerina DM; Amin S; Park SS; Gelboin HV; Baird WM
Chem Res Toxicol; 1997 May; 10(5):609-17. PubMed ID: 9168260
[TBL] [Abstract][Full Text] [Related]
13. Metabolism of benzo[a]pyrene to trans-7,8-dihydroxy-7, 8-dihydrobenzo[a]pyrene by recombinant human cytochrome P450 1B1 and purified liver epoxide hydrolase.
Shimada T; Gillam EM; Oda Y; Tsumura F; Sutter TR; Guengerich FP; Inoue K
Chem Res Toxicol; 1999 Jul; 12(7):623-9. PubMed ID: 10409402
[TBL] [Abstract][Full Text] [Related]
14. Benzo[a]pyrene-7,8-dihydrodiol promotes checkpoint activation and G2/M arrest in human bronchoalveolar carcinoma H358 cells.
Caino MC; Oliva JL; Jiang H; Penning TM; Kazanietz MG
Mol Pharmacol; 2007 Mar; 71(3):744-50. PubMed ID: 17114299
[TBL] [Abstract][Full Text] [Related]
15. Metabolic enzyme induction by HepG2 cells exposed to oxygenated and nonoxygenated polycyclic aromatic hydrocarbons.
Misaki K; Matsui S; Matsuda T
Chem Res Toxicol; 2007 Feb; 20(2):277-83. PubMed ID: 17253728
[TBL] [Abstract][Full Text] [Related]
16. Specificity of human aldo-keto reductases, NAD(P)H:quinone oxidoreductase, and carbonyl reductases to redox-cycle polycyclic aromatic hydrocarbon diones and 4-hydroxyequilenin-o-quinone.
Shultz CA; Quinn AM; Park JH; Harvey RG; Bolton JL; Maser E; Penning TM
Chem Res Toxicol; 2011 Dec; 24(12):2153-66. PubMed ID: 21910479
[TBL] [Abstract][Full Text] [Related]
17. Activation of polycyclic aromatic hydrocarbon trans-dihydrodiol proximate carcinogens by human aldo-keto reductase (AKR1C) enzymes and their functional overexpression in human lung carcinoma (A549) cells.
Palackal NT; Lee SH; Harvey RG; Blair IA; Penning TM
J Biol Chem; 2002 Jul; 277(27):24799-808. PubMed ID: 11978787
[TBL] [Abstract][Full Text] [Related]
18. Induction of CYP1A1 and CYP1B1 by benzo(k)fluoranthene and benzo(a)pyrene in T-47D human breast cancer cells: roles of PAH interactions and PAH metabolites.
Spink DC; Wu SJ; Spink BC; Hussain MM; Vakharia DD; Pentecost BT; Kaminsky LS
Toxicol Appl Pharmacol; 2008 Feb; 226(3):213-24. PubMed ID: 17919675
[TBL] [Abstract][Full Text] [Related]
19. The role of 12 cDNA-expressed human, rodent, and rabbit cytochromes P450 in the metabolism of benzo[a]pyrene and benzo[a]pyrene trans-7,8-dihydrodiol.
Shou M; Korzekwa KR; Crespi CL; Gonzalez FJ; Gelboin HV
Mol Carcinog; 1994 Jul; 10(3):159-68. PubMed ID: 8043197
[TBL] [Abstract][Full Text] [Related]
20. Evidence for the aldo-keto reductase pathway of polycyclic aromatic trans-dihydrodiol activation in human lung A549 cells.
Park JH; Mangal D; Tacka KA; Quinn AM; Harvey RG; Blair IA; Penning TM
Proc Natl Acad Sci U S A; 2008 May; 105(19):6846-51. PubMed ID: 18474869
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
