BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

372 related articles for article (PubMed ID: 17702746)

  • 1. CD44 regulates hepatocyte growth factor-mediated vascular integrity. Role of c-Met, Tiam1/Rac1, dynamin 2, and cortactin.
    Singleton PA; Salgia R; Moreno-Vinasco L; Moitra J; Sammani S; Mirzapoiazova T; Garcia JG
    J Biol Chem; 2007 Oct; 282(42):30643-57. PubMed ID: 17702746
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Akt-mediated transactivation of the S1P1 receptor in caveolin-enriched microdomains regulates endothelial barrier enhancement by oxidized phospholipids.
    Singleton PA; Chatchavalvanich S; Fu P; Xing J; Birukova AA; Fortune JA; Klibanov AM; Garcia JG; Birukov KG
    Circ Res; 2009 Apr; 104(8):978-86. PubMed ID: 19286607
    [TBL] [Abstract][Full Text] [Related]  

  • 3. HGF attenuates thrombin-induced endothelial permeability by Tiam1-mediated activation of the Rac pathway and by Tiam1/Rac-dependent inhibition of the Rho pathway.
    Birukova AA; Alekseeva E; Mikaelyan A; Birukov KG
    FASEB J; 2007 Sep; 21(11):2776-86. PubMed ID: 17428964
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hepatocyte growth factor triggers distinct mechanisms of Asef and Tiam1 activation to induce endothelial barrier enhancement.
    Higginbotham K; Tian Y; Gawlak G; Moldobaeva N; Shah A; Birukova AA
    Cell Signal; 2014 Nov; 26(11):2306-16. PubMed ID: 25101856
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of sphingosine 1-phosphate-induced endothelial cytoskeletal rearrangement and barrier enhancement by S1P1 receptor, PI3 kinase, Tiam1/Rac1, and alpha-actinin.
    Singleton PA; Dudek SM; Chiang ET; Garcia JG
    FASEB J; 2005 Oct; 19(12):1646-56. PubMed ID: 16195373
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Critical role of S1PR1 and integrin β4 in HGF/c-Met-mediated increases in vascular integrity.
    Ephstein Y; Singleton PA; Chen W; Wang L; Salgia R; Kanteti P; Dudek SM; Garcia JG; Jacobson JR
    J Biol Chem; 2013 Jan; 288(4):2191-200. PubMed ID: 23212923
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Prostaglandins PGE(2) and PGI(2) promote endothelial barrier enhancement via PKA- and Epac1/Rap1-dependent Rac activation.
    Birukova AA; Zagranichnaya T; Fu P; Alekseeva E; Chen W; Jacobson JR; Birukov KG
    Exp Cell Res; 2007 Jul; 313(11):2504-20. PubMed ID: 17493609
    [TBL] [Abstract][Full Text] [Related]  

  • 8. High-molecular-weight hyaluronan is a novel inhibitor of pulmonary vascular leakiness.
    Singleton PA; Mirzapoiazova T; Guo Y; Sammani S; Mambetsariev N; Lennon FE; Moreno-Vinasco L; Garcia JG
    Am J Physiol Lung Cell Mol Physiol; 2010 Nov; 299(5):L639-51. PubMed ID: 20709728
    [TBL] [Abstract][Full Text] [Related]  

  • 9. HGF-induced formation of the MET-AXL-ELMO2-DOCK180 complex promotes RAC1 activation, receptor clustering, and cancer cell migration and invasion.
    Li W; Xiong X; Abdalla A; Alejo S; Zhu L; Lu F; Sun H
    J Biol Chem; 2018 Oct; 293(40):15397-15418. PubMed ID: 30108175
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Asef controls vascular endothelial permeability and barrier recovery in the lung.
    Tian X; Tian Y; Gawlak G; Meng F; Kawasaki Y; Akiyama T; Birukova AA
    Mol Biol Cell; 2015 Feb; 26(4):636-50. PubMed ID: 25518936
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tiam1 and Rac1 are required for platelet-activating factor-induced endothelial junctional disassembly and increase in vascular permeability.
    Knezevic II; Predescu SA; Neamu RF; Gorovoy MS; Knezevic NM; Easington C; Malik AB; Predescu DN
    J Biol Chem; 2009 Feb; 284(8):5381-94. PubMed ID: 19095647
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Asef mediates HGF protective effects against LPS-induced lung injury and endothelial barrier dysfunction.
    Meng F; Meliton A; Moldobaeva N; Mutlu G; Kawasaki Y; Akiyama T; Birukova AA
    Am J Physiol Lung Cell Mol Physiol; 2015 Mar; 308(5):L452-63. PubMed ID: 25539852
    [TBL] [Abstract][Full Text] [Related]  

  • 13. IQGAP1 regulates endothelial barrier function via EB1-cortactin cross talk.
    Tian Y; Tian X; Gawlak G; O'Donnell JJ; Sacks DB; Birukova AA
    Mol Cell Biol; 2014 Sep; 34(18):3546-58. PubMed ID: 25022754
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CD44 interaction with tiam1 promotes Rac1 signaling and hyaluronic acid-mediated breast tumor cell migration.
    Bourguignon LY; Zhu H; Shao L; Chen YW
    J Biol Chem; 2000 Jan; 275(3):1829-38. PubMed ID: 10636882
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Transactivation of sphingosine 1-phosphate receptors is essential for vascular barrier regulation. Novel role for hyaluronan and CD44 receptor family.
    Singleton PA; Dudek SM; Ma SF; Garcia JG
    J Biol Chem; 2006 Nov; 281(45):34381-93. PubMed ID: 16963454
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Endothelial cell barrier enhancement by ATP is mediated by the small GTPase Rac and cortactin.
    Jacobson JR; Dudek SM; Singleton PA; Kolosova IA; Verin AD; Garcia JG
    Am J Physiol Lung Cell Mol Physiol; 2006 Aug; 291(2):L289-95. PubMed ID: 16825658
    [TBL] [Abstract][Full Text] [Related]  

  • 17. MET Signaling Mediates Intestinal Crypt-Villus Development, Regeneration, and Adenoma Formation and Is Promoted by Stem Cell CD44 Isoforms.
    Joosten SPJ; Zeilstra J; van Andel H; Mijnals RC; Zaunbrecher J; Duivenvoorden AAM; van de Wetering M; Clevers H; Spaargaren M; Pals ST
    Gastroenterology; 2017 Oct; 153(4):1040-1053.e4. PubMed ID: 28716720
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Guanine nucleotide exchange factor Dock7 mediates HGF-induced glioblastoma cell invasion via Rac activation.
    Murray DW; Didier S; Chan A; Paulino V; Van Aelst L; Ruggieri R; Tran NL; Byrne AT; Symons M
    Br J Cancer; 2014 Mar; 110(5):1307-15. PubMed ID: 24518591
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of End Binding Protein-1 in endothelial permeability response to barrier-disruptive and barrier-enhancing agonists.
    Tian X; Ohmura T; Shah AS; Son S; Tian Y; Birukova AA
    Cell Signal; 2017 Jan; 29():1-11. PubMed ID: 27667566
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hyaluronan-CD44 interaction with Rac1-dependent protein kinase N-gamma promotes phospholipase Cgamma1 activation, Ca(2+) signaling, and cortactin-cytoskeleton function leading to keratinocyte adhesion and differentiation.
    Bourguignon LY; Singleton PA; Diedrich F
    J Biol Chem; 2004 Jul; 279(28):29654-69. PubMed ID: 15123640
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.