323 related articles for article (PubMed ID: 17702750)
1. Long-acting kappa opioid antagonists disrupt receptor signaling and produce noncompetitive effects by activating c-Jun N-terminal kinase.
Bruchas MR; Yang T; Schreiber S; Defino M; Kwan SC; Li S; Chavkin C
J Biol Chem; 2007 Oct; 282(41):29803-11. PubMed ID: 17702750
[TBL] [Abstract][Full Text] [Related]
2. Sciatic nerve ligation-induced proliferation of spinal cord astrocytes is mediated by kappa opioid activation of p38 mitogen-activated protein kinase.
Xu M; Bruchas MR; Ippolito DL; Gendron L; Chavkin C
J Neurosci; 2007 Mar; 27(10):2570-81. PubMed ID: 17344394
[TBL] [Abstract][Full Text] [Related]
3. Long-Term Reduction of Kappa Opioid Receptor Function by the Biased Ligand, Norbinaltorphimine, Requires c-Jun N-Terminal Kinase Activity and New Protein Synthesis in Peripheral Sensory Neurons.
Jamshidi RJ; Sullivan LC; Jacobs BA; Chavera TA; Berg KA; Clarke WP
J Pharmacol Exp Ther; 2016 Nov; 359(2):319-328. PubMed ID: 27605628
[TBL] [Abstract][Full Text] [Related]
4. Kappa opioid receptor activation of p38 MAPK is GRK3- and arrestin-dependent in neurons and astrocytes.
Bruchas MR; Macey TA; Lowe JD; Chavkin C
J Biol Chem; 2006 Jun; 281(26):18081-9. PubMed ID: 16648139
[TBL] [Abstract][Full Text] [Related]
5. Duration of action of a broad range of selective κ-opioid receptor antagonists is positively correlated with c-Jun N-terminal kinase-1 activation.
Melief EJ; Miyatake M; Carroll FI; Béguin C; Carlezon WA; Cohen BM; Grimwood S; Mitch CH; Rorick-Kehn L; Chavkin C
Mol Pharmacol; 2011 Nov; 80(5):920-9. PubMed ID: 21832171
[TBL] [Abstract][Full Text] [Related]
6. Reactive oxygen species (ROS) generation is stimulated by κ opioid receptor activation through phosphorylated c-Jun N-terminal kinase and inhibited by p38 mitogen-activated protein kinase (MAPK) activation.
Schattauer SS; Bedini A; Summers F; Reilly-Treat A; Andrews MM; Land BB; Chavkin C
J Biol Chem; 2019 Nov; 294(45):16884-16896. PubMed ID: 31575661
[TBL] [Abstract][Full Text] [Related]
7. Behavioral Pharmacology of Novel Kappa Opioid Receptor Antagonists in Rats.
Page S; Mavrikaki MM; Lintz T; Puttick D; Roberts E; Rosen H; Carroll FI; Carlezon WA; Chartoff EH
Int J Neuropsychopharmacol; 2019 Nov; 22(11):735-745. PubMed ID: 31613314
[TBL] [Abstract][Full Text] [Related]
8. Regulation of Kappa Opioid Receptor Inactivation Depends on Sex and Cellular Site of Antagonist Action.
Reichard KL; Newton KA; Rivera ZMG; Sotero de Menezes PM; Schattauer SS; Land BB; Chavkin C
Mol Pharmacol; 2020 Nov; 98(5):548-558. PubMed ID: 32913138
[TBL] [Abstract][Full Text] [Related]
9. Kappa Opioid Receptor-Induced Aversion Requires p38 MAPK Activation in VTA Dopamine Neurons.
Ehrich JM; Messinger DI; Knakal CR; Kuhar JR; Schattauer SS; Bruchas MR; Zweifel LS; Kieffer BL; Phillips PE; Chavkin C
J Neurosci; 2015 Sep; 35(37):12917-31. PubMed ID: 26377476
[TBL] [Abstract][Full Text] [Related]
10. Investigation of the role of βarrestin2 in kappa opioid receptor modulation in a mouse model of pruritus.
Morgenweck J; Frankowski KJ; Prisinzano TE; Aubé J; Bohn LM
Neuropharmacology; 2015 Dec; 99():600-9. PubMed ID: 26318102
[TBL] [Abstract][Full Text] [Related]
11. Estrogen Regulation of GRK2 Inactivates Kappa Opioid Receptor Signaling Mediating Analgesia, But Not Aversion.
Abraham AD; Schattauer SS; Reichard KL; Cohen JH; Fontaine HM; Song AJ; Johnson SD; Land BB; Chavkin C
J Neurosci; 2018 Sep; 38(37):8031-8043. PubMed ID: 30076211
[TBL] [Abstract][Full Text] [Related]
12. Phosphoproteomic approach for agonist-specific signaling in mouse brains: mTOR pathway is involved in κ opioid aversion.
Liu JJ; Chiu YT; DiMattio KM; Chen C; Huang P; Gentile TA; Muschamp JW; Cowan A; Mann M; Liu-Chen LY
Neuropsychopharmacology; 2019 Apr; 44(5):939-949. PubMed ID: 30082888
[TBL] [Abstract][Full Text] [Related]
13. Locus coeruleus kappa-opioid receptors modulate reinstatement of cocaine place preference through a noradrenergic mechanism.
Al-Hasani R; McCall JG; Foshage AM; Bruchas MR
Neuropsychopharmacology; 2013 Nov; 38(12):2484-97. PubMed ID: 23787819
[TBL] [Abstract][Full Text] [Related]
14. Effectiveness of analogs of the kappa opioid receptor antagonist (3R)-7-hydroxy-N-((1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide (JDTic) to reduce U50,488-induced diuresis and stress-induced cocaine reinstatement in rats.
Beardsley PM; Pollard GT; Howard JL; Carroll FI
Psychopharmacology (Berl); 2010 Jun; 210(2):189-98. PubMed ID: 20372878
[TBL] [Abstract][Full Text] [Related]
15. Stress-induced p38 mitogen-activated protein kinase activation mediates kappa-opioid-dependent dysphoria.
Bruchas MR; Land BB; Aita M; Xu M; Barot SK; Li S; Chavkin C
J Neurosci; 2007 Oct; 27(43):11614-23. PubMed ID: 17959804
[TBL] [Abstract][Full Text] [Related]
16. 14-3-3γ mediates the long-term inhibition of peripheral kappa opioid receptor antinociceptive signaling by norbinaltorphimine.
Wedemeyer MJ; Jennings EM; Smith HR; Chavera TS; Jamshidi RJ; Berg KA; Clarke WP
Neuropharmacology; 2022 Dec; 220():109251. PubMed ID: 36126728
[TBL] [Abstract][Full Text] [Related]
17. Prolonged kappa opioid receptor phosphorylation mediated by G-protein receptor kinase underlies sustained analgesic tolerance.
McLaughlin JP; Myers LC; Zarek PE; Caron MG; Lefkowitz RJ; Czyzyk TA; Pintar JE; Chavkin C
J Biol Chem; 2004 Jan; 279(3):1810-8. PubMed ID: 14597630
[TBL] [Abstract][Full Text] [Related]
18. Antisense mapping KOR-1: evidence for multiple kappa analgesic mechanisms.
Pasternak KR; Rossi GC; Zuckerman A; Pasternak GW
Brain Res; 1999 May; 826(2):289-92. PubMed ID: 10224306
[TBL] [Abstract][Full Text] [Related]
19. Pharmacodynamic Relationships between Duration of Action of JDTic-like Kappa-Opioid Receptor Antagonists and Their Brain and Plasma Pharmacokinetics in Rats.
Owens SM; Pollard GT; Howard JL; Fennell TR; Snyder RW; Carroll FI
ACS Chem Neurosci; 2016 Dec; 7(12):1737-1745. PubMed ID: 27700049
[TBL] [Abstract][Full Text] [Related]
20. Behavioral stress may increase the rewarding valence of cocaine-associated cues through a dynorphin/kappa-opioid receptor-mediated mechanism without affecting associative learning or memory retrieval mechanisms.
Schindler AG; Li S; Chavkin C
Neuropsychopharmacology; 2010 Aug; 35(9):1932-42. PubMed ID: 20445500
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]