These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

202 related articles for article (PubMed ID: 17704171)

  • 1. Solution conformation of wild-type and mutant IgG3 and IgG4 immunoglobulins using crystallohydrodynamics: possible implications for complement activation.
    Lu Y; Harding SE; Michaelsen TE; Longman E; Davis KG; Ortega A; Grossmann JG; Sandlie I; García de la Torre J
    Biophys J; 2007 Dec; 93(11):3733-44. PubMed ID: 17704171
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Fab conformations in the solution structure of human immunoglobulin G4 (IgG4) restrict access to its Fc region: implications for functional activity.
    Rayner LE; Hui GK; Gor J; Heenan RK; Dalby PA; Perkins SJ
    J Biol Chem; 2014 Jul; 289(30):20740-56. PubMed ID: 24876381
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Crystallohydrodynamics of protein assemblies: Combining sedimentation, viscometry, and x-ray scattering.
    Lu Y; Longman E; Davis KG; Ortega A; Grossmann JG; Michaelsen TE; de la Torre JG; Harding SE
    Biophys J; 2006 Sep; 91(5):1688-97. PubMed ID: 16766619
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Solution structures of human myeloma IgG3 antibody reveal extended Fab and Fc regions relative to the other IgG subclasses.
    Spiteri VA; Goodall M; Doutch J; Rambo RP; Gor J; Perkins SJ
    J Biol Chem; 2021 Sep; 297(3):100995. PubMed ID: 34302810
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The solution structure of the human IgG2 subclass is distinct from those for human IgG1 and IgG4 providing an explanation for their discrete functions.
    Hui GK; Gardener AD; Begum H; Eldrid C; Thalassinos K; Gor J; Perkins SJ
    J Biol Chem; 2019 Jul; 294(28):10789-10806. PubMed ID: 31088911
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of complement by an IgG molecule without a genetic hinge.
    Brekke OH; Michaelsen TE; Sandin R; Sandlie I
    Nature; 1993 Jun; 363(6430):628-30. PubMed ID: 8510754
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Influence of the hinge region on complement activation, C1q binding, and segmental flexibility in chimeric human immunoglobulins.
    Tan LK; Shopes RJ; Oi VT; Morrison SL
    Proc Natl Acad Sci U S A; 1990 Jan; 87(1):162-6. PubMed ID: 2296577
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Crystallohydrodynamics for solving the hydration problem for multi-domain proteins: open physiological conformations for human IgG.
    Carrasco B; Garcia de la Torre J; Davis KG; Jones S; Athwal D; Walters C; Burton DR; Harding SE
    Biophys Chem; 2001 Nov; 93(2-3):181-96. PubMed ID: 11804725
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Estimating domain orientation of two human antibody IgG4 chimeras by crystallohydrodynamics.
    Longman E; Kreusel K; Tendler SB; Fiebrig I; King K; Adair J; O'Shea P; Ortega A; Garcia de la Torre J; Harding SE
    Eur Biophys J; 2003 Aug; 32(5):503-10. PubMed ID: 12811430
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Masking of the Fc region in human IgG4 by constrained X-ray scattering modelling: implications for antibody function and therapy.
    Abe Y; Gor J; Bracewell DG; Perkins SJ; Dalby PA
    Biochem J; 2010 Nov; 432(1):101-11. PubMed ID: 20722630
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural determinants of unique properties of human IgG4-Fc.
    Davies AM; Rispens T; Ooijevaar-de Heer P; Gould HJ; Jefferis R; Aalberse RC; Sutton BJ
    J Mol Biol; 2014 Feb; 426(3):630-44. PubMed ID: 24211234
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Atomistic Modeling of Scattering Curves for Human IgG1/4 Reveals New Structure-Function Insights.
    Wright DW; Elliston ELK; Hui GK; Perkins SJ
    Biophys J; 2019 Dec; 117(11):2101-2119. PubMed ID: 31708160
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Chimeric mouse human IgG3 antibodies with an IgG4-like hinge region induce complement-mediated lysis more efficiently than IgG3 with normal hinge.
    Norderhaug L; Brekke OH; Bremnes B; Sandin R; Aase A; Michaelsen TE; Sandlie I
    Eur J Immunol; 1991 Oct; 21(10):2379-84. PubMed ID: 1915551
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The extended hinge region of IgG3 is not required for high phagocytic capacity mediated by Fc gamma receptors, but the heavy chains must be disulfide bonded.
    Aase A; Sandlie I; Norderhaug L; Brekke OH; Michaelsen TE
    Eur J Immunol; 1993 Jul; 23(7):1546-51. PubMed ID: 8325331
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Enhancement of complement activation and cytolysis of human IgG3 by deletion of hinge exons.
    Michaelsen TE; Aase A; Westby C; Sandlie I
    Scand J Immunol; 1990 Nov; 32(5):517-28. PubMed ID: 2125362
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Human IgG1, IgG3, and IgG3 Hinge-Truncated Mutants Show Different Protection Capabilities against Meningococci Depending on the Target Antigen and Epitope Specificity.
    Giuntini S; Granoff DM; Beernink PT; Ihle O; Bratlie D; Michaelsen TE
    Clin Vaccine Immunol; 2016 Aug; 23(8):698-706. PubMed ID: 27307451
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The Fab and Fc fragments of IgA1 exhibit a different arrangement from that in IgG: a study by X-ray and neutron solution scattering and homology modelling.
    Boehm MK; Woof JM; Kerr MA; Perkins SJ
    J Mol Biol; 1999 Mar; 286(5):1421-47. PubMed ID: 10064707
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The structural requirements for complement activation by IgG: does it hinge on the hinge?
    Brekke OH; Michaelsen TE; Sandlie I
    Immunol Today; 1995 Feb; 16(2):85-90. PubMed ID: 7888072
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure of a Therapeutic Full-Length Anti-NPRA IgG4 Antibody: Dissecting Conformational Diversity.
    Blech M; Hörer S; Kuhn AB; Kube S; Göddeke H; Kiefer H; Zang Y; Alber Y; Kast SM; Westermann M; Tully MD; Schäfer LV; Garidel P
    Biophys J; 2019 May; 116(9):1637-1649. PubMed ID: 31023536
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Solution structure of human and mouse immunoglobulin M by synchrotron X-ray scattering and molecular graphics modelling. A possible mechanism for complement activation.
    Perkins SJ; Nealis AS; Sutton BJ; Feinstein A
    J Mol Biol; 1991 Oct; 221(4):1345-66. PubMed ID: 1942055
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.