BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

316 related articles for article (PubMed ID: 17706199)

  • 1. Enhanced sialylation of EPO by overexpression of UDP-GlcNAc 2-epimerase/ManAc kinase containing a sialuria mutation in CHO cells.
    Bork K; Reutter W; Weidemann W; Horstkorte R
    FEBS Lett; 2007 Sep; 581(22):4195-8. PubMed ID: 17706199
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Enhanced sialylation of recombinant human erythropoietin in Chinese hamster ovary cells by combinatorial engineering of selected genes.
    Son YD; Jeong YT; Park SY; Kim JH
    Glycobiology; 2011 Aug; 21(8):1019-28. PubMed ID: 21436238
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The intracellular concentration of sialic acid regulates the polysialylation of the neural cell adhesion molecule.
    Bork K; Reutter W; Gerardy-Schahn R; Horstkorte R
    FEBS Lett; 2005 Sep; 579(22):5079-83. PubMed ID: 16137682
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulation and pathophysiological implications of UDP-GlcNAc 2-epimerase/ManNAc kinase (GNE) as the key enzyme of sialic acid biosynthesis.
    Reinke SO; Lehmer G; Hinderlich S; Reutter W
    Biol Chem; 2009 Jul; 390(7):591-9. PubMed ID: 19426133
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Enhanced sialylation of recombinant erythropoietin in genetically engineered Chinese-hamster ovary cells.
    Jeong YT; Choi O; Son YD; Park SY; Kim JH
    Biotechnol Appl Biochem; 2009 Apr; 52(Pt 4):283-91. PubMed ID: 18590515
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Lec3 Chinese hamster ovary mutants lack UDP-N-acetylglucosamine 2-epimerase activity because of mutations in the epimerase domain of the Gne gene.
    Hong Y; Stanley P
    J Biol Chem; 2003 Dec; 278(52):53045-54. PubMed ID: 14561743
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Engineering intracellular CMP-sialic acid metabolism into insect cells and methods to enhance its generation.
    Viswanathan K; Narang S; Hinderlich S; Lee YC; Betenbaugh MJ
    Biochemistry; 2005 May; 44(20):7526-34. PubMed ID: 15895995
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The collapsin response mediator protein 1 (CRMP-1) and the promyelocytic leukemia zinc finger protein (PLZF) bind to UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE), the key enzyme of sialic acid biosynthesis.
    Weidemann W; Stelzl U; Lisewski U; Bork K; Wanker EE; Hinderlich S; Horstkorte R
    FEBS Lett; 2006 Dec; 580(28-29):6649-54. PubMed ID: 17118363
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The homozygous M712T mutation of UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase results in reduced enzyme activities but not in altered overall cellular sialylation in hereditary inclusion body myopathy.
    Hinderlich S; Salama I; Eisenberg I; Potikha T; Mantey LR; Yarema KJ; Horstkorte R; Argov Z; Sadeh M; Reutter W; Mitrani-Rosenbaum S
    FEBS Lett; 2004 May; 566(1-3):105-9. PubMed ID: 15147877
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Engineering sialic acid synthetic ability into insect cells: identifying metabolic bottlenecks and devising strategies to overcome them.
    Viswanathan K; Lawrence S; Hinderlich S; Yarema KJ; Lee YC; Betenbaugh MJ
    Biochemistry; 2003 Dec; 42(51):15215-25. PubMed ID: 14690432
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Localization of UDP-GlcNAc 2-epimerase/ManAc kinase (GNE) in the Golgi complex and the nucleus of mammalian cells.
    Krause S; Hinderlich S; Amsili S; Horstkorte R; Wiendl H; Argov Z; Mitrani-Rosenbaum S; Lochmüller H
    Exp Cell Res; 2005 Apr; 304(2):365-79. PubMed ID: 15748884
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Biosynthesis of N-acetylneuraminic acid in cells lacking UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase.
    Hinderlich S; Berger M; Keppler OT; Pawlita M; Reutter W
    Biol Chem; 2001 Feb; 382(2):291-7. PubMed ID: 11308027
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular modeling of the bifunctional enzyme UDP-GlcNAc 2-epimerase/ManNAc kinase and predictions of structural effects of mutations associated with HIBM and sialuria.
    Kurochkina N; Yardeni T; Huizing M
    Glycobiology; 2010 Mar; 20(3):322-37. PubMed ID: 19917666
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Enhancing recombinant glycoprotein sialylation through CMP-sialic acid transporter over expression in Chinese hamster ovary cells.
    Wong NS; Yap MG; Wang DI
    Biotechnol Bioeng; 2006 Apr; 93(5):1005-16. PubMed ID: 16432895
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Tumour suppressor p16(INK4a) - anoikis-favouring decrease in N/O-glycan/cell surface sialylation by down-regulation of enzymes in sialic acid biosynthesis in tandem in a pancreatic carcinoma model.
    Amano M; Eriksson H; Manning JC; Detjen KM; André S; Nishimura S; Lehtiö J; Gabius HJ
    FEBS J; 2012 Nov; 279(21):4062-80. PubMed ID: 22943525
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sialuria in a Portuguese girl: clinical, biochemical, and molecular characteristics.
    Ferreira H; Seppala R; Pinto R; Huizing M; Martins E; Braga AC; Gomes L; Krasnewich DM; Sa Miranda MC; Gahl WA
    Mol Genet Metab; 1999 Jun; 67(2):131-7. PubMed ID: 10356312
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Use of a cell-free system to determine UDP-N-acetylglucosamine 2-epimerase and N-acetylmannosamine kinase activities in human hereditary inclusion body myopathy.
    Sparks SE; Ciccone C; Lalor M; Orvisky E; Klootwijk R; Savelkoul PJ; Dalakas MC; Krasnewich DM; Gahl WA; Huizing M
    Glycobiology; 2005 Nov; 15(11):1102-10. PubMed ID: 15987957
    [TBL] [Abstract][Full Text] [Related]  

  • 18. No overall hyposialylation in hereditary inclusion body myopathy myoblasts carrying the homozygous M712T GNE mutation.
    Salama I; Hinderlich S; Shlomai Z; Eisenberg I; Krause S; Yarema K; Argov Z; Lochmuller H; Reutter W; Dabby R; Sadeh M; Ben-Bassat H; Mitrani-Rosenbaum S
    Biochem Biophys Res Commun; 2005 Mar; 328(1):221-6. PubMed ID: 15670773
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Influence of UDP-GlcNAc 2-epimerase/ManNAc kinase mutant proteins on hereditary inclusion body myopathy.
    Penner J; Mantey LR; Elgavish S; Ghaderi D; Cirak S; Berger M; Krause S; Lucka L; Voit T; Mitrani-Rosenbaum S; Hinderlich S
    Biochemistry; 2006 Mar; 45(9):2968-77. PubMed ID: 16503651
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The key enzyme of sialic acid biosynthesis (GNE) promotes neurite outgrowth of PC12 cells.
    Kontou M; Weidemann W; Bauer C; Reutter W; Horstkorte R
    Neuroreport; 2008 Aug; 19(12):1239-42. PubMed ID: 18628673
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.