These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
5. Cytoplasmic and nuclear distribution of the protein complexes mTORC1 and mTORC2: rapamycin triggers dephosphorylation and delocalization of the mTORC2 components rictor and sin1. Rosner M; Hengstschläger M Hum Mol Genet; 2008 Oct; 17(19):2934-48. PubMed ID: 18614546 [TBL] [Abstract][Full Text] [Related]
6. Regulation of mTORC1 and mTORC2 complex assembly by phosphatidic acid: competition with rapamycin. Toschi A; Lee E; Xu L; Garcia A; Gadir N; Foster DA Mol Cell Biol; 2009 Mar; 29(6):1411-20. PubMed ID: 19114562 [TBL] [Abstract][Full Text] [Related]
7. Increased AKT S473 phosphorylation after mTORC1 inhibition is rictor dependent and does not predict tumor cell response to PI3K/mTOR inhibition. Breuleux M; Klopfenstein M; Stephan C; Doughty CA; Barys L; Maira SM; Kwiatkowski D; Lane HA Mol Cancer Ther; 2009 Apr; 8(4):742-53. PubMed ID: 19372546 [TBL] [Abstract][Full Text] [Related]
8. Inhibition of 14-3-3 binding to Rictor of mTORC2 for Akt phosphorylation at Ser473 is regulated by selenoprotein W. Jeon YH; Park YH; Kwon JH; Lee JH; Kim IY Biochim Biophys Acta; 2013 Oct; 1833(10):2135-42. PubMed ID: 23680186 [TBL] [Abstract][Full Text] [Related]
9. Identification of Protor as a novel Rictor-binding component of mTOR complex-2. Pearce LR; Huang X; Boudeau J; Pawłowski R; Wullschleger S; Deak M; Ibrahim AF; Gourlay R; Magnuson MA; Alessi DR Biochem J; 2007 Aug; 405(3):513-22. PubMed ID: 17461779 [TBL] [Abstract][Full Text] [Related]
10. Involvement of mTORC1 and mTORC2 in regulation of glioblastoma multiforme growth and motility. Gulati N; Karsy M; Albert L; Murali R; Jhanwar-Uniyal M Int J Oncol; 2009 Oct; 35(4):731-40. PubMed ID: 19724909 [TBL] [Abstract][Full Text] [Related]
11. Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. Sarbassov DD; Ali SM; Kim DH; Guertin DA; Latek RR; Erdjument-Bromage H; Tempst P; Sabatini DM Curr Biol; 2004 Jul; 14(14):1296-302. PubMed ID: 15268862 [TBL] [Abstract][Full Text] [Related]
12. SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. Jacinto E; Facchinetti V; Liu D; Soto N; Wei S; Jung SY; Huang Q; Qin J; Su B Cell; 2006 Oct; 127(1):125-37. PubMed ID: 16962653 [TBL] [Abstract][Full Text] [Related]
13. mTORC1 and mTORC2 regulate insulin secretion through Akt in INS-1 cells. Le Bacquer O; Queniat G; Gmyr V; Kerr-Conte J; Lefebvre B; Pattou F J Endocrinol; 2013 Jan; 216(1):21-9. PubMed ID: 23092880 [TBL] [Abstract][Full Text] [Related]
14. Identification of rictor as a novel substrate of Polo-like kinase 1. Shao T; Liu X Cell Cycle; 2015; 14(5):755-60. PubMed ID: 25714006 [TBL] [Abstract][Full Text] [Related]
15. Human cytomegalovirus infection alters the substrate specificities and rapamycin sensitivities of raptor- and rictor-containing complexes. Kudchodkar SB; Yu Y; Maguire TG; Alwine JC Proc Natl Acad Sci U S A; 2006 Sep; 103(38):14182-7. PubMed ID: 16959881 [TBL] [Abstract][Full Text] [Related]
16. IKK interacts with rictor and regulates mTORC2. Xu Y; Lai E; Liu J; Lin J; Yang C; Jia C; Li Y; Bai X; Li M Cell Signal; 2013 Nov; 25(11):2239-45. PubMed ID: 23872070 [TBL] [Abstract][Full Text] [Related]
17. Characterization of Rictor phosphorylation sites reveals direct regulation of mTOR complex 2 by S6K1. Dibble CC; Asara JM; Manning BD Mol Cell Biol; 2009 Nov; 29(21):5657-70. PubMed ID: 19720745 [TBL] [Abstract][Full Text] [Related]
18. mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1). García-Martínez JM; Alessi DR Biochem J; 2008 Dec; 416(3):375-85. PubMed ID: 18925875 [TBL] [Abstract][Full Text] [Related]
19. mTORC2 promotes type I insulin-like growth factor receptor and insulin receptor activation through the tyrosine kinase activity of mTOR. Yin Y; Hua H; Li M; Liu S; Kong Q; Shao T; Wang J; Luo Y; Wang Q; Luo T; Jiang Y Cell Res; 2016 Jan; 26(1):46-65. PubMed ID: 26584640 [TBL] [Abstract][Full Text] [Related]
20. Functional Role of mTORC2 versus Integrin-Linked Kinase in Mediating Ser473-Akt Phosphorylation in PTEN-Negative Prostate and Breast Cancer Cell Lines. Lee SL; Chou CC; Chuang HC; Hsu EC; Chiu PC; Kulp SK; Byrd JC; Chen CS PLoS One; 2013; 8(6):e67149. PubMed ID: 23840605 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]