These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation. Lamothe B; Besse A; Campos AD; Webster WK; Wu H; Darnay BG J Biol Chem; 2007 Feb; 282(6):4102-12. PubMed ID: 17135271 [TBL] [Abstract][Full Text] [Related]
3. Two different classes of E2 ubiquitin-conjugating enzymes are required for the mono-ubiquitination of proteins and elongation by polyubiquitin chains with a specific topology. Windheim M; Peggie M; Cohen P Biochem J; 2008 Feb; 409(3):723-9. PubMed ID: 18042044 [TBL] [Abstract][Full Text] [Related]
4. Interactions between the quality control ubiquitin ligase CHIP and ubiquitin conjugating enzymes. Xu Z; Kohli E; Devlin KI; Bold M; Nix JC; Misra S BMC Struct Biol; 2008 May; 8():26. PubMed ID: 18485199 [TBL] [Abstract][Full Text] [Related]
5. Distinct regulation of Ubc13 functions by the two ubiquitin-conjugating enzyme variants Mms2 and Uev1A. Andersen PL; Zhou H; Pastushok L; Moraes T; McKenna S; Ziola B; Ellison MJ; Dixit VM; Xiao W J Cell Biol; 2005 Aug; 170(5):745-55. PubMed ID: 16129784 [TBL] [Abstract][Full Text] [Related]
6. Molecular basis of Lys-63-linked polyubiquitination inhibition by the interaction between human deubiquitinating enzyme OTUB1 and ubiquitin-conjugating enzyme UBC13. Sato Y; Yamagata A; Goto-Ito S; Kubota K; Miyamoto R; Nakada S; Fukai S J Biol Chem; 2012 Jul; 287(31):25860-8. PubMed ID: 22679021 [TBL] [Abstract][Full Text] [Related]
7. Energetics and specificity of interactions within Ub.Uev.Ubc13 human ubiquitin conjugation complexes. McKenna S; Hu J; Moraes T; Xiao W; Ellison MJ; Spyracopoulos L Biochemistry; 2003 Jul; 42(26):7922-30. PubMed ID: 12834344 [TBL] [Abstract][Full Text] [Related]
8. Oligomerization-primed coiled-coil domain interaction with Ubc13 confers processivity to TRAF6 ubiquitin ligase activity. Hu L; Xu J; Xie X; Zhou Y; Tao P; Li H; Han X; Wang C; Liu J; Xu P; Neculai D; Xia Z Nat Commun; 2017 Oct; 8(1):814. PubMed ID: 28993672 [TBL] [Abstract][Full Text] [Related]
9. Ubiquitin-conjugating enzyme complex Uev1A-Ubc13 promotes breast cancer metastasis through nuclear factor-кB mediated matrix metalloproteinase-1 gene regulation. Wu Z; Shen S; Zhang Z; Zhang W; Xiao W Breast Cancer Res; 2014 Jul; 16(4):R75. PubMed ID: 25022892 [TBL] [Abstract][Full Text] [Related]
10. Chaperoned ubiquitylation--crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complex. Zhang M; Windheim M; Roe SM; Peggie M; Cohen P; Prodromou C; Pearl LH Mol Cell; 2005 Nov; 20(4):525-38. PubMed ID: 16307917 [TBL] [Abstract][Full Text] [Related]
11. Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain. Deng L; Wang C; Spencer E; Yang L; Braun A; You J; Slaughter C; Pickart C; Chen ZJ Cell; 2000 Oct; 103(2):351-61. PubMed ID: 11057907 [TBL] [Abstract][Full Text] [Related]
12. Targeting TRAF6 E3 ligase activity with a small-molecule inhibitor combats autoimmunity. Brenke JK; Popowicz GM; Schorpp K; Rothenaigner I; Roesner M; Meininger I; Kalinski C; Ringelstetter L; R'kyek O; Jürjens G; Vincendeau M; Plettenburg O; Sattler M; Krappmann D; Hadian K J Biol Chem; 2018 Aug; 293(34):13191-13203. PubMed ID: 29950522 [TBL] [Abstract][Full Text] [Related]
13. Uev1A-Ubc13 catalyzes K63-linked ubiquitination of RHBDF2 to promote TACE maturation. Zhang Y; Li Y; Yang X; Wang J; Wang R; Qian X; Zhang W; Xiao W Cell Signal; 2018 Jan; 42():155-164. PubMed ID: 29069608 [TBL] [Abstract][Full Text] [Related]
14. The activity of TRAF RING homo- and heterodimers is regulated by zinc finger 1. Middleton AJ; Budhidarmo R; Das A; Zhu J; Foglizzo M; Mace PD; Day CL Nat Commun; 2017 Nov; 8(1):1788. PubMed ID: 29176576 [TBL] [Abstract][Full Text] [Related]
15. The molecular basis of lysine 48 ubiquitin chain synthesis by Ube2K. Middleton AJ; Day CL Sci Rep; 2015 Nov; 5():16793. PubMed ID: 26592444 [TBL] [Abstract][Full Text] [Related]
16. The coiled-coil domain of TRAF6 is essential for its auto-ubiquitination. Yang K; Zhu J; Sun S; Tang Y; Zhang B; Diao L; Wang C Biochem Biophys Res Commun; 2004 Nov; 324(1):432-9. PubMed ID: 15465037 [TBL] [Abstract][Full Text] [Related]
18. Structure and interactions of the ubiquitin-conjugating enzyme variant human Uev1a: implications for enzymatic synthesis of polyubiquitin chains. Hau DD; Lewis MJ; Saltibus LF; Pastushok L; Xiao W; Spyracopoulos L Biochemistry; 2006 Aug; 45(32):9866-77. PubMed ID: 16893187 [TBL] [Abstract][Full Text] [Related]
19. Certain pairs of ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) synthesize nondegradable forked ubiquitin chains containing all possible isopeptide linkages. Kim HT; Kim KP; Lledias F; Kisselev AF; Scaglione KM; Skowyra D; Gygi SP; Goldberg AL J Biol Chem; 2007 Jun; 282(24):17375-86. PubMed ID: 17426036 [TBL] [Abstract][Full Text] [Related]
20. Deamidation disrupts native and transient contacts to weaken the interaction between UBC13 and RING-finger E3 ligases. Mohanty P; Agrata R; Habibullah BI; G S A; Das R Elife; 2019 Oct; 8():. PubMed ID: 31638574 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]