BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

259 related articles for article (PubMed ID: 17711300)

  • 1. Intrinsic fluorescence reports a global conformational change in the N-lobe of human serum transferrin following iron release.
    James NG; Berger CL; Byrne SL; Smith VC; MacGillivray RT; Mason AB
    Biochemistry; 2007 Sep; 46(37):10603-11. PubMed ID: 17711300
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Composition of pH-sensitive triad in C-lobe of human serum transferrin. Comparison to sequences of ovotransferrin and lactoferrin provides insight into functional differences in iron release.
    Halbrooks PJ; Giannetti AM; Klein JS; Björkman PJ; Larouche JR; Smith VC; MacGillivray RT; Everse SJ; Mason AB
    Biochemistry; 2005 Nov; 44(47):15451-60. PubMed ID: 16300393
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inequivalent contribution of the five tryptophan residues in the C-lobe of human serum transferrin to the fluorescence increase when iron is released.
    James NG; Byrne SL; Steere AN; Smith VC; MacGillivray RT; Mason AB
    Biochemistry; 2009 Apr; 48(13):2858-67. PubMed ID: 19281173
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutational analysis of C-lobe ligands of human serum transferrin: insights into the mechanism of iron release.
    Mason AB; Halbrooks PJ; James NG; Connolly SA; Larouche JR; Smith VC; MacGillivray RT; Chasteen ND
    Biochemistry; 2005 Jun; 44(22):8013-21. PubMed ID: 15924420
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Investigation of the mechanism of iron release from the C-lobe of human serum transferrin: mutational analysis of the role of a pH sensitive triad.
    Halbrooks PJ; He QY; Briggs SK; Everse SJ; Smith VC; MacGillivray RT; Mason AB
    Biochemistry; 2003 Apr; 42(13):3701-7. PubMed ID: 12667060
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural and functional consequences of binding site mutations in transferrin: crystal structures of the Asp63Glu and Arg124Ala mutants of the N-lobe of human transferrin.
    Baker HM; He QY; Briggs SK; Mason AB; Baker EN
    Biochemistry; 2003 Jun; 42(23):7084-9. PubMed ID: 12795604
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dual role of Lys206-Lys296 interaction in human transferrin N-lobe: iron-release trigger and anion-binding site.
    He QY; Mason AB; Tam BM; MacGillivray RT; Woodworth RC
    Biochemistry; 1999 Jul; 38(30):9704-11. PubMed ID: 10423249
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Iron release from transferrin, its C-lobe, and their complexes with transferrin receptor: presence of N-lobe accelerates release from C-lobe at endosomal pH.
    Zak O; Aisen P
    Biochemistry; 2003 Oct; 42(42):12330-4. PubMed ID: 14567694
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Iron release is reduced by mutations of lysines 206 and 296 in recombinant N-terminal half-transferrin.
    Steinlein LM; Ligman CM; Kessler S; Ikeda RA
    Biochemistry; 1998 Sep; 37(39):13696-703. PubMed ID: 9753457
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ligand-induced conformational change in transferrins: crystal structure of the open form of the N-terminal half-molecule of human transferrin.
    Jeffrey PD; Bewley MC; MacGillivray RT; Mason AB; Woodworth RC; Baker EN
    Biochemistry; 1998 Oct; 37(40):13978-86. PubMed ID: 9760232
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Interlobe communication in human serum transferrin: metal binding and conformational dynamics investigated by electrospray ionization mass spectrometry.
    Gumerov DR; Mason AB; Kaltashov IA
    Biochemistry; 2003 May; 42(18):5421-8. PubMed ID: 12731884
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structures of two mutants that probe the role in iron release of the dilysine pair in the N-lobe of human transferrin.
    Baker HM; Nurizzo D; Mason AB; Baker EN
    Acta Crystallogr D Biol Crystallogr; 2007 Mar; 63(Pt 3):408-14. PubMed ID: 17327678
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The mechanism of iron release from the transferrin-receptor 1 adduct.
    Hémadi M; Ha-Duong NT; El Hage Chahine JM
    J Mol Biol; 2006 May; 358(4):1125-36. PubMed ID: 16564538
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Tertiary structural changes and iron release from human serum transferrin.
    Mecklenburg SL; Donohoe RJ; Olah GA
    J Mol Biol; 1997 Aug; 270(5):739-50. PubMed ID: 9245601
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Incorporation of 5-hydroxytryptophan into transferrin and its receptor allows assignment of the pH induced changes in intrinsic fluorescence when iron is released.
    James NG; Byrne SL; Mason AB
    Biochim Biophys Acta; 2009 Mar; 1794(3):532-40. PubMed ID: 19103311
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Two high-resolution crystal structures of the recombinant N-lobe of human transferrin reveal a structural change implicated in iron release.
    MacGillivray RT; Moore SA; Chen J; Anderson BF; Baker H; Luo Y; Bewley M; Smith CA; Murphy ME; Wang Y; Mason AB; Woodworth RC; Brayer GD; Baker EN
    Biochemistry; 1998 Jun; 37(22):7919-28. PubMed ID: 9609685
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The oxalate effect on release of iron from human serum transferrin explained.
    Halbrooks PJ; Mason AB; Adams TE; Briggs SK; Everse SJ
    J Mol Biol; 2004 May; 339(1):217-26. PubMed ID: 15123433
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Transferrin, is a mixed chelate-protein ternary complex involved in the mechanism of iron uptake by serum-transferrin in vitro?
    Pakdaman R; Abdallah FB; El Hage Chahine JM
    J Mol Biol; 1999 Nov; 293(5):1273-84. PubMed ID: 10547300
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Spectral and metal-binding properties of three single-point tryptophan mutants of the human transferrin N-lobe.
    He QY; Mason AB; Lyons BA; Tam BM; Nguyen V; MacGillivray RT; Woodworth RC
    Biochem J; 2001 Mar; 354(Pt 2):423-9. PubMed ID: 11171122
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Camel lactoferrin, a transferrin-cum-lactoferrin: crystal structure of camel apolactoferrin at 2.6 A resolution and structural basis of its dual role.
    Khan JA; Kumar P; Paramasivam M; Yadav RS; Sahani MS; Sharma S; Srinivasan A; Singh TP
    J Mol Biol; 2001 Jun; 309(3):751-61. PubMed ID: 11397094
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.