BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

543 related articles for article (PubMed ID: 17713970)

  • 1. Substituted NDP-MSH peptides paired with mutant melanocortin-4 receptors demonstrate the role of transmembrane 6 in receptor activation.
    Fleck BA; Ling N; Chen C
    Biochemistry; 2007 Sep; 46(37):10473-83. PubMed ID: 17713970
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cysteine residues are involved in structure and function of melanocortin 1 receptor: Substitution of a cysteine residue in transmembrane segment two converts an agonist to antagonist.
    Frändberg PA; Doufexis M; Kapas S; Chhajlani V
    Biochem Biophys Res Commun; 2001 Mar; 281(4):851-7. PubMed ID: 11237737
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular mechanism of the intracellular segments of the melanocortin-4 receptor for NDP-MSH signaling.
    Yang Y; Chen M; Loux TJ; Georgeson KE; Harmon CM
    Biochemistry; 2005 May; 44(18):6971-9. PubMed ID: 15865442
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of putative agouti-related protein(87-132)-melanocortin-4 receptor interactions by homology molecular modeling and validation using chimeric peptide ligands.
    Wilczynski A; Wang XS; Joseph CG; Xiang Z; Bauzo RM; Scott JW; Sorensen NB; Shaw AM; Millard WJ; Richards NG; Haskell-Luevano C
    J Med Chem; 2004 Apr; 47(9):2194-207. PubMed ID: 15084118
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Three-dimensional molecular models of the hMC1R melanocortin receptor: complexes with melanotropin peptide agonists.
    Haskell-Luevano C; Sawyer TK; Trumpp-Kallmeyer S; Bikker JA; Humblet C; Gantz I; Hruby VJ
    Drug Des Discov; 1996 Dec; 14(3):197-211. PubMed ID: 9017363
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cyclic analogs of alpha-melanocyte-stimulating hormone (alphaMSH) with high agonist potency and selectivity at human melanocortin receptor 1b.
    Bednarek MA; MacNeil T; Tang R; Fong TM; Cabello MA; Maroto M; Teran A
    Peptides; 2008 Jun; 29(6):1010-7. PubMed ID: 18378043
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular interactions of nonpeptide agonists and antagonists with the melanocortin-4 receptor.
    Fleck BA; Chen C; Yang W; Huntley R; Markison S; Nickolls SA; Foster AC; Hoare SR
    Biochemistry; 2005 Nov; 44(44):14494-508. PubMed ID: 16262250
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery of prototype peptidomimetic agonists at the human melanocortin receptors MC1R and MC4R.
    Haskell-Luevano C; Hendrata S; North C; Sawyer TK; Hadley ME; Hruby VJ; Dickinson C; Gantz I
    J Med Chem; 1997 Jul; 40(14):2133-9. PubMed ID: 9216831
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Biological and conformational examination of stereochemical modifications using the template melanotropin peptide, Ac-Nle-c[Asp-His-Phe-Arg-Trp-Ala-Lys]-NH2, on human melanocortin receptors.
    Haskell-Luevano C; Nikiforovich G; Sharma SD; Yang YK; Dickinson C; Hruby VJ; Gantz I
    J Med Chem; 1997 May; 40(11):1738-48. PubMed ID: 9171884
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular basis of melanocortin-4 receptor for AGRP inverse agonism.
    Chen M; Celik A; Georgeson KE; Harmon CM; Yang Y
    Regul Pept; 2006 Sep; 136(1-3):40-9. PubMed ID: 16820227
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure and function of the potent cyclic and linear melanocortin analogues.
    Cho MK; Lee CJ; Lee CH; Li SZ; Lim SK; Baik JH; Lee W
    J Struct Biol; 2005 Jun; 150(3):300-8. PubMed ID: 15890278
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular determinants of ligand binding to the human melanocortin-4 receptor.
    Yang YK; Fong TM; Dickinson CJ; Mao C; Li JY; Tota MR; Mosley R; Van Der Ploeg LH; Gantz I
    Biochemistry; 2000 Dec; 39(48):14900-11. PubMed ID: 11101306
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular determination of agouti-related protein binding to human melanocortin-4 receptor.
    Yang Y; Chen M; Lai Y; Gantz I; Yagmurlu A; Georgeson KE; Harmon CM
    Mol Pharmacol; 2003 Jul; 64(1):94-103. PubMed ID: 12815165
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Proteochemometric modeling reveals the interaction site for Trp9 modified alpha-MSH peptides in melanocortin receptors.
    Lapinsh M; Prusis P; Petrovska R; Uhlén S; Mutule I; Veiksina S; Wikberg JE
    Proteins; 2007 May; 67(3):653-60. PubMed ID: 17357163
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular determinants of melanocortin 4 receptor ligand binding and MC4/MC3 receptor selectivity.
    Nickolls SA; Cismowski MI; Wang X; Wolff M; Conlon PJ; Maki RA
    J Pharmacol Exp Ther; 2003 Mar; 304(3):1217-27. PubMed ID: 12604699
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Pharmacological characterization of 40 human melanocortin-4 receptor polymorphisms with the endogenous proopiomelanocortin-derived agonists and the agouti-related protein (AGRP) antagonist.
    Xiang Z; Litherland SA; Sorensen NB; Proneth B; Wood MS; Shaw AM; Millard WJ; Haskell-Luevano C
    Biochemistry; 2006 Jun; 45(23):7277-88. PubMed ID: 16752916
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Studies of conformational isomerism in alpha-melanocyte stimulating hormone by design of cyclic analogues.
    Nikiforovich GV; Sharma SD; Hadley ME; Hruby VJ
    Biopolymers; 1998 Sep; 46(3):155-67. PubMed ID: 9699465
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Peptide and small molecules rescue the functional activity and agonist potency of dysfunctional human melanocortin-4 receptor polymorphisms.
    Xiang Z; Pogozheva ID; Sorenson NB; Wilczynski AM; Holder JR; Litherland SA; Millard WJ; Mosberg HI; Haskell-Luevano C
    Biochemistry; 2007 Jul; 46(28):8273-87. PubMed ID: 17590021
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Contribution of the conserved amino acids of the melanocortin-4 receptor in [corrected] [Nle4,D-Phe7]-alpha-melanocyte-stimulating [corrected] hormone binding and signaling.
    Chen M; Cai M; Aprahamian CJ; Georgeson KE; Hruby V; Harmon CM; Yang Y
    J Biol Chem; 2007 Jul; 282(30):21712-9. PubMed ID: 17545153
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure activity studies of the melanocortin-4 receptor by in vitro mutagenesis: identification of agouti-related protein (AGRP), melanocortin agonist and synthetic peptide antagonist interaction determinants.
    Haskell-Luevano C; Cone RD; Monck EK; Wan YP
    Biochemistry; 2001 May; 40(20):6164-79. PubMed ID: 11352754
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 28.