These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

73 related articles for article (PubMed ID: 17717108)

  • 1. Ligand-directed signaling: 50 ways to find a lover.
    Michel MC; Alewijnse AE
    Mol Pharmacol; 2007 Nov; 72(5):1097-9. PubMed ID: 17717108
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The evasive nature of drug efficacy: implications for drug discovery.
    Galandrin S; Oligny-Longpré G; Bouvier M
    Trends Pharmacol Sci; 2007 Aug; 28(8):423-30. PubMed ID: 17659355
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Conformational rearrangements and signaling cascades involved in ligand-biased mitogen-activated protein kinase signaling through the beta1-adrenergic receptor.
    Galandrin S; Oligny-Longpré G; Bonin H; Ogawa K; Galés C; Bouvier M
    Mol Pharmacol; 2008 Jul; 74(1):162-72. PubMed ID: 18403719
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Label-free optical biosensor for ligand-directed functional selectivity acting on beta(2) adrenoceptor in living cells.
    Fang Y; Ferrie AM
    FEBS Lett; 2008 Mar; 582(5):558-64. PubMed ID: 18242178
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Collateral efficacy in drug discovery: taking advantage of the good (allosteric) nature of 7TM receptors.
    Kenakin T
    Trends Pharmacol Sci; 2007 Aug; 28(8):407-15. PubMed ID: 17629960
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Quantification of ligand bias for clinically relevant β2-adrenergic receptor ligands: implications for drug taxonomy.
    van der Westhuizen ET; Breton B; Christopoulos A; Bouvier M
    Mol Pharmacol; 2014 Mar; 85(3):492-509. PubMed ID: 24366668
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Functional selectivity of GPCR ligand stereoisomers: new pharmacological opportunities.
    Seifert R; Dove S
    Mol Pharmacol; 2009 Jan; 75(1):13-8. PubMed ID: 19001067
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Functional selectivity and classical concepts of quantitative pharmacology.
    Urban JD; Clarke WP; von Zastrow M; Nichols DE; Kobilka B; Weinstein H; Javitch JA; Roth BL; Christopoulos A; Sexton PM; Miller KJ; Spedding M; Mailman RB
    J Pharmacol Exp Ther; 2007 Jan; 320(1):1-13. PubMed ID: 16803859
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Functional selectivity through protean and biased agonism: who steers the ship?
    Kenakin T
    Mol Pharmacol; 2007 Dec; 72(6):1393-401. PubMed ID: 17901198
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural basis for ligand binding and specificity in adrenergic receptors: implications for GPCR-targeted drug discovery.
    Huber T; Menon S; Sakmar TP
    Biochemistry; 2008 Oct; 47(42):11013-23. PubMed ID: 18821775
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Relaxin-3, INSL5, and their receptors.
    Liu C; Lovenberg TW
    Results Probl Cell Differ; 2008; 46():213-37. PubMed ID: 18236022
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Current status of inverse agonism at serotonin2A (5-HT2A) and 5-HT2C receptors.
    Aloyo VJ; Berg KA; Spampinato U; Clarke WP; Harvey JA
    Pharmacol Ther; 2009 Feb; 121(2):160-73. PubMed ID: 19109993
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The beta3-adrenoceptor agonist 4-[[(Hexylamino)carbonyl]amino]-N-[4-[2-[[(2S)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]-phenyl]-benzenesulfonamide (L755507) and antagonist (S)-N-[4-[2-[[3-[3-(acetamidomethyl)phenoxy]-2-hydroxypropyl]amino]-ethyl]phenyl]benzenesulfonamide (L748337) activate different signaling pathways in Chinese hamster ovary-K1 cells stably expressing the human beta3-adrenoceptor.
    Sato M; Hutchinson DS; Evans BA; Summers RJ
    Mol Pharmacol; 2008 Nov; 74(5):1417-28. PubMed ID: 18684840
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A conservative, single-amino acid substitution in the second cytoplasmic domain of the human Serotonin2C receptor alters both ligand-dependent and -independent receptor signaling.
    Berg KA; Dunlop J; Sanchez T; Silva M; Clarke WP
    J Pharmacol Exp Ther; 2008 Mar; 324(3):1084-92. PubMed ID: 18065501
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cellular signaling is potentially regulated by cell density in receptor trafficking networks.
    Zi Z; Klipp E
    FEBS Lett; 2007 Oct; 581(24):4589-95. PubMed ID: 17825822
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Stably overexpressed human Frizzled-2 signals through the beta-catenin pathway and does not activate Ca2+-mobilization in Human Embryonic Kidney 293 cells.
    Verkaar F; van Rosmalen JW; Smits JF; Blankesteijn WM; Zaman GJ
    Cell Signal; 2009 Jan; 21(1):22-33. PubMed ID: 18929644
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ligand-based gene expression profiling reveals novel roles of glucocorticoid receptor in cardiac metabolism.
    Yoshikawa N; Nagasaki M; Sano M; Tokudome S; Ueno K; Shimizu N; Imoto S; Miyano S; Suematsu M; Fukuda K; Morimoto C; Tanaka H
    Am J Physiol Endocrinol Metab; 2009 Jun; 296(6):E1363-73. PubMed ID: 19293335
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Computational insights into the mechanism of ligand unbinding and selectivity of estrogen receptors.
    Shen J; Li W; Liu G; Tang Y; Jiang H
    J Phys Chem B; 2009 Jul; 113(30):10436-44. PubMed ID: 19583238
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Agonist-directed trafficking of signalling at serotonin 5-HT2A, 5-HT2B and 5-HT2C-VSV receptors mediated Gq/11 activation and calcium mobilisation in CHO cells.
    Cussac D; Boutet-Robinet E; Ailhaud MC; Newman-Tancredi A; Martel JC; Danty N; Rauly-Lestienne I
    Eur J Pharmacol; 2008 Oct; 594(1-3):32-8. PubMed ID: 18703043
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Nitric oxide mechanisms of nebivolol.
    Maffei A; Lembo G
    Ther Adv Cardiovasc Dis; 2009 Aug; 3(4):317-27. PubMed ID: 19443516
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.