BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

169 related articles for article (PubMed ID: 17719032)

  • 1. Intrathecal infusion of a Ca(2+)-permeable AMPA channel blocker slows loss of both motor neurons and of the astrocyte glutamate transporter, GLT-1 in a mutant SOD1 rat model of ALS.
    Yin HZ; Tang DT; Weiss JH
    Exp Neurol; 2007 Oct; 207(2):177-85. PubMed ID: 17719032
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Intrathecal infusion of BMAA induces selective motor neuron damage and astrogliosis in the ventral horn of the spinal cord.
    Yin HZ; Yu S; Hsu CI; Liu J; Acab A; Wu R; Tao A; Chiang BJ; Weiss JH
    Exp Neurol; 2014 Nov; 261():1-9. PubMed ID: 24918341
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Marked synergism between mutant SOD1 and glutamate transport inhibition in the induction of motor neuronal degeneration in spinal cord slice cultures.
    Yin HZ; Weiss JH
    Brain Res; 2012 Apr; 1448():153-62. PubMed ID: 22370146
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Loss of metabotropic glutamate receptor-mediated regulation of glutamate transport in chemically activated astrocytes in a rat model of amyotrophic lateral sclerosis.
    Vermeiren C; Hemptinne I; Vanhoutte N; Tilleux S; Maloteaux JM; Hermans E
    J Neurochem; 2006 Feb; 96(3):719-31. PubMed ID: 16371010
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Increased internalisation and degradation of GLT-1 glial glutamate transporter in a cell model for familial amyotrophic lateral sclerosis (ALS).
    Vanoni C; Massari S; Losa M; Carrega P; Perego C; Conforti L; Pietrini G
    J Cell Sci; 2004 Oct; 117(Pt 22):5417-26. PubMed ID: 15466883
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Transgenic SOD1 G93A mice develop reduced GLT-1 in spinal cord without alterations in cerebrospinal fluid glutamate levels.
    Bendotti C; Tortarolo M; Suchak SK; Calvaresi N; Carvelli L; Bastone A; Rizzi M; Rattray M; Mennini T
    J Neurochem; 2001 Nov; 79(4):737-46. PubMed ID: 11723166
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Endothelin-1 is over-expressed in amyotrophic lateral sclerosis and induces motor neuron cell death.
    Ranno E; D'Antoni S; Spatuzza M; Berretta A; Laureanti F; Bonaccorso CM; Pellitteri R; Longone P; Spalloni A; Iyer AM; Aronica E; Catania MV
    Neurobiol Dis; 2014 May; 65():160-71. PubMed ID: 24423643
    [TBL] [Abstract][Full Text] [Related]  

  • 8. GLT1 overexpression in SOD1(G93A) mouse cervical spinal cord does not preserve diaphragm function or extend disease.
    Li K; Hala TJ; Seetharam S; Poulsen DJ; Wright MC; Lepore AC
    Neurobiol Dis; 2015 Jun; 78():12-23. PubMed ID: 25818008
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activation of mGlu3 metabotropic glutamate receptors enhances GDNF and GLT-1 formation in the spinal cord and rescues motor neurons in the SOD-1 mouse model of amyotrophic lateral sclerosis.
    Battaglia G; Riozzi B; Bucci D; Di Menna L; Molinaro G; Pallottino S; Nicoletti F; Bruno V
    Neurobiol Dis; 2015 Feb; 74():126-36. PubMed ID: 25434487
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The VPAC2 agonist peptide histidine isoleucine (PHI) up-regulates glutamate transport in the corpus callosum of a rat model of amyotrophic lateral sclerosis (hSOD1G93A) by inhibiting caspase-3 mediated inactivation of GLT-1a.
    Goursaud S; Focant MC; Berger JV; Nizet Y; Maloteaux JM; Hermans E
    FASEB J; 2011 Oct; 25(10):3674-86. PubMed ID: 21730107
    [TBL] [Abstract][Full Text] [Related]  

  • 11. TNF-α triggers rapid membrane insertion of Ca(2+) permeable AMPA receptors into adult motor neurons and enhances their susceptibility to slow excitotoxic injury.
    Yin HZ; Hsu CI; Yu S; Rao SD; Sorkin LS; Weiss JH
    Exp Neurol; 2012 Dec; 238(2):93-102. PubMed ID: 22921461
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Connexin 43 in astrocytes contributes to motor neuron toxicity in amyotrophic lateral sclerosis.
    Almad AA; Doreswamy A; Gross SK; Richard JP; Huo Y; Haughey N; Maragakis NJ
    Glia; 2016 Jul; 64(7):1154-69. PubMed ID: 27083773
    [TBL] [Abstract][Full Text] [Related]  

  • 13. GLT-1 glutamate transporter levels are unchanged in mice expressing G93A human mutant SOD1.
    Deitch JS; Alexander GM; Del Valle L; Heiman-Patterson TD
    J Neurol Sci; 2002 Jan; 193(2):117-26. PubMed ID: 11790392
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Distinct expression and regulation of the glutamate transporter isoforms GLT-1a and GLT-1b in cultured astrocytes from a rat model of amyotrophic lateral sclerosis (hSOD1G93A).
    Goursaud S; Maloteaux JM; Hermans E
    Neurochem Int; 2009; 55(1-3):28-34. PubMed ID: 19428804
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Impaired spinal cord glutamate transport capacity and reduced sensitivity to riluzole in a transgenic superoxide dismutase mutant rat model of amyotrophic lateral sclerosis.
    Dunlop J; Beal McIlvain H; She Y; Howland DS
    J Neurosci; 2003 Mar; 23(5):1688-96. PubMed ID: 12629173
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Differential involvement of vesicular and glial glutamate transporters around spinal α-motoneurons in the pathogenesis of SOD1
    Ohgomori T; Yamasaki R; Takeuchi H; Kadomatsu K; Kira JI; Jinno S
    Neuroscience; 2017 Jul; 356():114-124. PubMed ID: 28526579
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Increased expression of the glial glutamate transporter EAAT2 modulates excitotoxicity and delays the onset but not the outcome of ALS in mice.
    Guo H; Lai L; Butchbach ME; Stockinger MP; Shan X; Bishop GA; Lin CL
    Hum Mol Genet; 2003 Oct; 12(19):2519-32. PubMed ID: 12915461
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tardive decrease of astrocytic glutamate transporter protein in transgenic mice with ALS-linked mutant SOD1.
    Warita H; Manabe Y; Murakami T; Shiote M; Shiro Y; Hayashi T; Nagano I; Shoji M; Abe K
    Neurol Res; 2002 Sep; 24(6):577-81. PubMed ID: 12238624
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Expression of SOD1 G93A or wild-type SOD1 in primary cultures of astrocytes down-regulates the glutamate transporter GLT-1: lack of involvement of oxidative stress.
    Tortarolo M; Crossthwaite AJ; Conforti L; Spencer JP; Williams RJ; Bendotti C; Rattray M
    J Neurochem; 2004 Jan; 88(2):481-93. PubMed ID: 14690536
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Altered astrocytic response to activation in SOD1(G93A) mice and its implications on amyotrophic lateral sclerosis pathogenesis.
    Benkler C; Ben-Zur T; Barhum Y; Offen D
    Glia; 2013 Mar; 61(3):312-26. PubMed ID: 23280929
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.