223 related articles for article (PubMed ID: 17722061)
1. Maternal embryonic leucine zipper kinase is a key regulator of the proliferation of malignant brain tumors, including brain tumor stem cells.
Nakano I; Masterman-Smith M; Saigusa K; Paucar AA; Horvath S; Shoemaker L; Watanabe M; Negro A; Bajpai R; Howes A; Lelievre V; Waschek JA; Lazareff JA; Freije WA; Liau LM; Gilbertson RJ; Cloughesy TF; Geschwind DH; Nelson SF; Mischel PS; Terskikh AV; Kornblum HI
J Neurosci Res; 2008 Jan; 86(1):48-60. PubMed ID: 17722061
[TBL] [Abstract][Full Text] [Related]
2. Maternal embryonic leucine zipper kinase transcript abundance correlates with malignancy grade in human astrocytomas.
Marie SK; Okamoto OK; Uno M; Hasegawa AP; Oba-Shinjo SM; Cohen T; Camargo AA; Kosoy A; Carlotti CG; Toledo S; Moreira-Filho CA; Zago MA; Simpson AJ; Caballero OL
Int J Cancer; 2008 Feb; 122(4):807-15. PubMed ID: 17960622
[TBL] [Abstract][Full Text] [Related]
3. Methods for analysis of brain tumor stem cell and neural stem cell self-renewal.
Nakano I; Kornblum HI
Methods Mol Biol; 2009; 568():37-56. PubMed ID: 19582420
[TBL] [Abstract][Full Text] [Related]
4. Siomycin A targets brain tumor stem cells partially through a MELK-mediated pathway.
Nakano I; Joshi K; Visnyei K; Hu B; Watanabe M; Lam D; Wexler E; Saigusa K; Nakamura Y; Laks DR; Mischel PS; Viapiano M; Kornblum HI
Neuro Oncol; 2011 Jun; 13(6):622-34. PubMed ID: 21558073
[TBL] [Abstract][Full Text] [Related]
5. Effective growth-suppressive activity of maternal embryonic leucine-zipper kinase (MELK) inhibitor against small cell lung cancer.
Inoue H; Kato T; Olugbile S; Tamura K; Chung S; Miyamoto T; Matsuo Y; Salgia R; Nakamura Y; Park JH
Oncotarget; 2016 Mar; 7(12):13621-33. PubMed ID: 26871945
[TBL] [Abstract][Full Text] [Related]
6. Maternal embryonic leucine zipper kinase (MELK) regulates multipotent neural progenitor proliferation.
Nakano I; Paucar AA; Bajpai R; Dougherty JD; Zewail A; Kelly TK; Kim KJ; Ou J; Groszer M; Imura T; Freije WA; Nelson SF; Sofroniew MV; Wu H; Liu X; Terskikh AV; Geschwind DH; Kornblum HI
J Cell Biol; 2005 Aug; 170(3):413-27. PubMed ID: 16061694
[TBL] [Abstract][Full Text] [Related]
7. MELK and EZH2 Cooperate to Regulate Medulloblastoma Cancer Stem-like Cell Proliferation and Differentiation.
Liu H; Sun Q; Sun Y; Zhang J; Yuan H; Pang S; Qi X; Wang H; Zhang M; Zhang H; Yu C; Gu C
Mol Cancer Res; 2017 Sep; 15(9):1275-1286. PubMed ID: 28536141
[TBL] [Abstract][Full Text] [Related]
8. MELK-dependent FOXM1 phosphorylation is essential for proliferation of glioma stem cells.
Joshi K; Banasavadi-Siddegowda Y; Mo X; Kim SH; Mao P; Kig C; Nardini D; Sobol RW; Chow LM; Kornblum HI; Waclaw R; Beullens M; Nakano I
Stem Cells; 2013 Jun; 31(6):1051-63. PubMed ID: 23404835
[TBL] [Abstract][Full Text] [Related]
9. Maternal embryonic leucine zipper kinase (MELK) reduces replication stress in glioblastoma cells.
Kig C; Beullens M; Beke L; Van Eynde A; Linders JT; Brehmer D; Bollen M
J Biol Chem; 2013 Aug; 288(33):24200-12. PubMed ID: 23836907
[TBL] [Abstract][Full Text] [Related]
10. Tumor-specific activation of the C-JUN/MELK pathway regulates glioma stem cell growth in a p53-dependent manner.
Gu C; Banasavadi-Siddegowda YK; Joshi K; Nakamura Y; Kurt H; Gupta S; Nakano I
Stem Cells; 2013 May; 31(5):870-81. PubMed ID: 23339114
[TBL] [Abstract][Full Text] [Related]
11. Maternal embryonic leucine zipper kinase/murine protein serine-threonine kinase 38 is a promising therapeutic target for multiple cancers.
Gray D; Jubb AM; Hogue D; Dowd P; Kljavin N; Yi S; Bai W; Frantz G; Zhang Z; Koeppen H; de Sauvage FJ; Davis DP
Cancer Res; 2005 Nov; 65(21):9751-61. PubMed ID: 16266996
[TBL] [Abstract][Full Text] [Related]
12. Maternal embryonic leucine zipper kinase: A novel biomarker and a potential therapeutic target of cervical cancer.
Wang J; Wang Y; Shen F; Xu Y; Zhang Y; Zou X; Zhou J; Chen Y
Cancer Med; 2018 Nov; 7(11):5665-5678. PubMed ID: 30334367
[TBL] [Abstract][Full Text] [Related]
13. MELK inhibition targets cancer stem cells through downregulation of SOX2 expression in head and neck cancer cells.
Ren L; Deng B; Saloura V; Park JH; Nakamura Y
Oncol Rep; 2019 Apr; 41(4):2540-2548. PubMed ID: 30720113
[TBL] [Abstract][Full Text] [Related]
14. Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia.
Alachkar H; Mutonga MB; Metzeler KH; Fulton N; Malnassy G; Herold T; Spiekermann K; Bohlander SK; Hiddemann W; Matsuo Y; Stock W; Nakamura Y
Oncotarget; 2014 Dec; 5(23):12371-82. PubMed ID: 25365263
[TBL] [Abstract][Full Text] [Related]
15. Maternal embryonic leucine zipper kinase: key kinase for stem cell phenotype in glioma and other cancers.
Ganguly R; Hong CS; Smith LG; Kornblum HI; Nakano I
Mol Cancer Ther; 2014 Jun; 13(6):1393-8. PubMed ID: 24795222
[TBL] [Abstract][Full Text] [Related]
16. Maternal embryonic leucine zipper kinase is upregulated and required in mammary tumor-initiating cells in vivo.
Hebbard LW; Maurer J; Miller A; Lesperance J; Hassell J; Oshima RG; Terskikh AV
Cancer Res; 2010 Nov; 70(21):8863-73. PubMed ID: 20861186
[TBL] [Abstract][Full Text] [Related]
17. Multi-kinase inhibitor C1 triggers mitotic catastrophe of glioma stem cells mainly through MELK kinase inhibition.
Minata M; Gu C; Joshi K; Nakano-Okuno M; Hong C; Nguyen CH; Kornblum HI; Molla A; Nakano I
PLoS One; 2014; 9(4):e92546. PubMed ID: 24739874
[TBL] [Abstract][Full Text] [Related]
18. Resistance of colorectal cancer cells to radiation and 5-FU is associated with MELK expression.
Choi S; Ku JL
Biochem Biophys Res Commun; 2011 Aug; 412(2):207-13. PubMed ID: 21806965
[TBL] [Abstract][Full Text] [Related]
19. Involvement of maternal embryonic leucine zipper kinase (MELK) in mammary carcinogenesis through interaction with Bcl-G, a pro-apoptotic member of the Bcl-2 family.
Lin ML; Park JH; Nishidate T; Nakamura Y; Katagiri T
Breast Cancer Res; 2007; 9(1):R17. PubMed ID: 17280616
[TBL] [Abstract][Full Text] [Related]
20. Maternal Embryonic Leucine Zipper Kinase is Associated with Metastasis in Triple-negative Breast Cancer.
Xie X; Chauhan GB; Edupuganti R; Kogawa T; Park J; Tacam M; Tan AW; Mughees M; Vidhu F; Liu DD; Taliaferro JM; Pitner MK; Browning LS; Lee JH; Shen Y; Wang J; Ueno NT; Krishnamurthy S; Hortobagyi GN; Tripathy D; Van Laere SJ; Bartholomeusz G; Dalby KN; Bartholomeusz C
Cancer Res Commun; 2023 Jun; 3(6):1078-1092. PubMed ID: 37377604
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
